Prempro Coupons & Prices

Prempro FAQs

How much does Prempro cost without insurance?

Without insurance, the average cash price of Prempro is $314.54 for 1, 28 Tablets Disp Pack. Pay as little as $208.23 for 1, 28 tablets Disp Pack and save up to 80% on other medications with a free SingleCare savings card.

How much does Prempro cost with insurance?

The copay on your Prempro prescription depends on your health insurance plan and coverage. You will have to check with your pharmacist to determine your cost with insurance. When you use SingleCare's discount card, Prempro costs $208.23 for 1, 28 tablets Disp Pack. Note: Your cost with our coupons may be cheaper than your cost with insurance.

Does Medicare cover Prempro and how much does it cost?

Some Medicare prescription plans may cover the cost of your Prempro prescription. Using a SingleCare savings card can get you significant discounts on your Prempro prescriptions. You can also use SingleCare coupons to get instant savings that may be even better than Medicare discounts.

How to save on Prempro

SingleCare coupons for Prempro can bring your cost down to $208.23 for 1, 28 tablets Disp Pack. Our prescription discount card is usually the quickest and easiest way to save on Prempro and other drugs. Eligible patients include anyone in the United States with a valid prescription. There are no other eligibility criteria or membership fees. People who use the SingleCare discount program can save up to 80% on prescription drug costs. Access the SingleCare website or mobile app to start saving today. 

Is there a generic of Prempro?

Prempro is a brand-name drug. Conjugated estrogens and medroxyprogesterone acetate are the ingredients in Prempro. A generic version of Prempro is not yet commercially available. You can use your Prempro coupon card at participating pharmacies to save money on Prempro or Prempro alternatives.

What is Prempro?

Prempro is a prescription drug that contains both estrogen and progestin as its active ingredients. Estrogen (conjugated estrogens in Prempro) and progestin (medroxyprogesterone acetate in Prempro) are female sex hormones used to treat symptoms of menopause. This medicine replaces estrogen that is no longer being made by the body. Estrogen helps with symptoms such as hot flashes and vaginal dryness, as well as prevents osteoporosis. Progestin is added to estrogen in hormone replacement therapy to lower the risk of uterine cancer in women with a uterus. Note: If a woman has had her uterus removed, there would be no need for her to use progestin.

What is the standard Prempro dosage?

Prempro is an oral tablet that is available in various strengths, and is taken once daily.

What are the side effects of Prempro?

Common side effects of Prempro include abdominal or back pain, weakness, nausea, headache, breast pain/breast changes, vaginal bleeding/spotting, and depression. 

Serious side effects may occur. These include increased risk of stroke, heart attacks, blood clots, and breast cancer. Prempro shouldn't be used if you have experienced unusual vaginal bleeding or if you are pregnant. 

Allergic reactions are rare. If you experience signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, get emergency medical help.

This is not a complete list of side effects. Other medical conditions are not compatible with Prempro use. Your doctor will be able to provide you with additional medical advice on other possible side effects. Consult your healthcare provider for more information and to see if Prempro is safe for you. 

What is the black box warning of Prempro?

A black box warning is the strongest warning required by the FDA. Prempro has a black box warning, which states:

Estrogen plus progestin:

• Estrogen plus progestion treatment should not be used to prevent cardiovascular disease or dementia.

• The Women’s Health Initiative (WHI) estrogen plus progestin substudy found increased risks of stroke, blood clots, heart attack, and breast cancer. The WHI Memory Study found estrogen and progestin to increase the risk of dementia in women 65 years and older. 

Estrogen alone:

• Women with a uterus who take estrogen (without a progestin) have a higher risk of endometrial cancer. (This is why women with a uterus are prescribed a progestin along with estrogen.)

• Estrogen-alone treatment should not be used to prevent cardiovascular disease or dementia. 

• Estrogen alone can increase the risk of strokes and blood clots, as well as increase the risk of dementia in women 65 years and older. 

Who should not take Prempro?

Before taking Prempro, tell your doctor about all of your medical conditions. Prempro is not appropriate for everyone. Individuals who should not take Prempro include:

• Women with undiagnosed genital bleeding

• Women with breast cancer, suspected breast cancer, or history or breast cancer

• Women with known or suspected estrogen-dependent cancer

• Women with deep vein thrombosis, pulmonary embolism, or a history of either of these conditions

• Women with certain medical conditions like stroke or heart attack or history of stroke or heart attack

• Women with liver problems

• Women who are pregnant or may be pregnant

• Women with protein C, protein S, or antithrombin deficiency or other similar disorders

Does Prempro interact with any medications? 

Before taking Prempro, tell your healthcare professional about any allergies to medications, as well as all of the medicines you take. This inclues prescription and OTC drugs, vitamins, and supplements.

Some drug interactions with Prempro include:

• Arimidex (anastrazole)

• Aromasin (exemestane)

• Biaxin (clarithromycin)

• Erythromycin

• Femara (letrozole)

• Grapefruit and grapefruit juice

• Lotronex (alosetron)

• Nizoral (ketoconazole)

• Phenobarbital 

• Rifampin

• Ritonavir

• Sporanox (itraconazole)

• St. John’s wort

• Tegretol (carbamazepine)

• Zanaflex (tizanidine)

This is not a full list of drug interactions, and others may occur. Consult your healthcare professional for a full list of drug interactions.

Is there a cheaper alternative to Prempro?

If you are looking to change to an alternative of Prempro, consult your healthcare provider. Only your healthcare provider can determine which drug is best for you. Some examples of Prempro alternatives include:

• Climara/Climara Pro transdermal patches

• CombiPatch transdermal patches

• Estrace vaginal cream

• Estring vaginal ring

• Premarin oral tablets

• Vagifem vaginal tablets

• Vivelle-Dot transdermal patches