Depo-Estradiol Coupons & Prices

Depo-Estradiol is a brand-name intramuscular injection that contains estradiol cypionate. It is prescribed to menopausal women to alleviate moderate to severe vasomotor symptoms, such as hot flashes, night sweats, and flushing. It is also prescribed to women who have a deficiency in estrog

0.2 Vial5ml of 5mg/mlEdit

Unlock members-only prices.Free signup.

Unlock an extra $3 off & more member perks.

Sign up, it’s free

Save an extra $3 on any eligible prescription below! Sign up for free

Members can save even more
and it's free to join

Depo-Estradiol coupon at Cvs Pharmacy
$188.10
$ 185.10
  • How is this calculated?

  • Price if you don’t sign up:

    $188.10

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $185.10

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Depo-Estradiol coupon at Kroger Pharmacy
$192.20
$ 189.20
  • How is this calculated?

  • Price if you don’t sign up:

    $192.20

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $189.20

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Depo-Estradiol coupon at Harris Teeter Pharmacy
$192.20
$ 189.20
  • How is this calculated?

  • Price if you don’t sign up:

    $192.20

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $189.20

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Depo-Estradiol coupon at Rite Aid Pharmacy
$198.45
$ 195.45
  • How is this calculated?

  • Price if you don’t sign up:

    $198.45

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $195.45

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Depo-Estradiol coupon at Walgreens Pharmacy
$198.96
$ 195.96
  • How is this calculated?

  • Price if you don’t sign up:

    $198.96

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $195.96

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Depo-Estradiol coupon at Food Lion Pharmacy
$ 197.23
$200.80
$ 197.80
  • How is this calculated?

  • Price if you don’t sign up:

    $200.80

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $197.80

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$200.80
$ 197.80
  • How is this calculated?

  • Price if you don’t sign up:

    $200.80

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $197.80

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 212.16

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

Keep your coupons handy with the free SingleCare app

Switch the free SingleCare app

4.8 avg rating
Get the app
About Depo-Estradiol

Depo-Estradiol is a brand-name intramuscular injection that contains estradiol cypionate. It is prescribed to menopausal women to alleviate moderate to severe vasomotor symptoms, such as hot flashes, night sweats, and flushing. It is also prescribed to women who have a deficiency in estrogen production or as hormonal therapy for transgender women. The average cash price of Depo-Estradiol is $216.77 for 1, 5ML of 5MG/ML Vial, but you can get a discount with a SingleCare Depo-Estradiol coupon. Ask the clinic or hospital where you receive Depo-Estradiol injections if they will accept a SingleCare Depo-Estradiol coupon; you could pay only $185.10 for 1, 5ml of 5mg/ml Vial.

Depo-Estradiol Price History & Information

Price History for Depo-Estradiol

1 count, 5ml of 5mg/ml

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Depo-Estradiol

1 count, 5ml of 5mg/ml
PharmacyDepo-Estradiol Retail PriceDepo-Estradiol SingleCare Price
CVS Pharmacy$206.28$180.03
Walmart$204.31$184.76
Walgreens$251.60$184.15
Kroger Pharmacy$217.53$178.71
Albertsons Pharmacy$210.70$182.55
Rite Aid Pharmacy$243.33$192.98

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Depo-Estradiol

Depo-Estradiol is a brand-name intramuscular injection that contains estradiol cypionate. It is prescribed to menopausal women to alleviate moderate to severe vasomotor symptoms, such as hot flashes, night sweats, and flushing. It is also prescribed to women who have a deficiency in estrogen production or as hormonal therapy for transgender women. The average cash price of Depo-Estradiol is $216.77 for 1, 5ML of 5MG/ML Vial, but you can get a discount with a SingleCare Depo-Estradiol coupon. Ask the clinic or hospital where you receive Depo-Estradiol injections if they will accept a SingleCare Depo-Estradiol coupon; you could pay only $185.10 for 1, 5ml of 5mg/ml Vial.

Depo-Estradiol FAQs

How much does Depo-Estradiol cost without insurance?

Depo-Estradiol can cost an average cash price of $216.77 for 1, 5ML of 5MG/ML Vial for uninsured customers. The actual cash price of Depo-Estradiol can vary depending on the dosage and quantity prescribed. A SingleCare Depo-Estradiol coupon could allow you to pay only $185.10 for 1, 5ml of 5mg/ml Vial. Ask the hospital or clinic where you receive Depo-Estradiol injections if they will accept SingleCare as a savings option.

How much does Depo-Estradiol cost with insurance?

Your copay for Depo-Estradiol with insurance will vary depending on your plan and the dosage required. Check with your insurance provider to determine your coverage for Depo-Estradiol. Depo-Estradiol may be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic or hospital where you receive Depo-Estradiol injections if they will accept a SingleCare Depo-Estradiol coupon; you could pay only $185.10 for 1, 5ml of 5mg/ml Vial if they do.

Does Medicare cover Depo-Estradiol and how much does it cost?

Depo-Estradiol is not usually covered under Medicare Part D and Medicare Advantage prescription drug plans. Instead, it may be covered under Medicare Part B as a medical benefit. If you're not covered, ask the clinic or hospital where you receive Depo-Estradiol injections if they will accept a SingleCare Depo-Estradiol coupon; you could pay only $185.10 for 1, 5ml of 5mg/ml Vial.

Is there a generic of Depo-Estradiol?

Depo-Estradiol is a brand-name injection. The generic name of Depo-Estradiol is estradiol cypionate. There may not be a generic version of Depo-Estradiol currently available. 

What is Depo-Estradiol?

Depo-Estradiol is a brand-name intramuscular injection that contains estradiol cypionate. It is prescribed to treat vasomotor symptoms caused by menopause, such as hot flashes, night sweats, and flushing. Depo-Estradiol may also help alleviate other symptoms of menopause, such as vaginal dryness. 

Depo-Estradiol is approved for women whose ovaries have stopped producing or produce too little estrogen. Depo-Estradiol is sometimes used off-label as hormonal therapy for transgender women.

Depo-Estradiol is administered as an injection by a healthcare professional once every 3 to 4 weeks. Consult with a healthcare provider to determine the appropriate dosage for you. The dosage can vary depending on the condition being treated.

What are the side effects of Depo-Estradiol?

The most common side effects of Depo-Estradiol include headache, bloating, stomach cramps, breast tenderness, irregular vaginal bleeding or spotting, and nausea or vomiting. Other side effects may include fluid retention, high blood pressure, high blood sugar levels, liver problems, uterine fibroids, vaginal yeast infections, and hair loss. 

Serious side effects include stroke, heart attack, breast cancer, and blood clots. Women who are 65 or older may be at an increased risk of developing dementia. Allergic reactions are uncommon but may include symptoms like rash, hives, or trouble breathing. Immediately seek medical attention if you show signs of an allergic reaction.

This is not a complete list of side effects. Consult with a healthcare provider about other possible side effects, warnings, and precautions associated with Depo-Estradiol. Tell your doctor about other medical conditions you have and other medications you may be taking before starting treatment with Depo-Estradiol.