Xgeva Coupons & Prices

Xgeva FAQs

How much does Xgeva cost without insurance?

Without insurance, Xgeva costs $3,736.21. A SingleCare Xgeva coupon may lower that price to $3,188.66 per 1, 1.7ml of 120mg/1.7ml Vial, provided the hospital or clinic where you receive your injection will accept SingleCare.

How much does Xgeva cost with insurance?

The insurance copay for Xgeva will vary depending on your plan and the price charged for Xgeva by the hospital or clinic where you get your injections. However, Xgeva may be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic or hospital where you receive Xgeva injections if they will accept a SingleCare Xgeva coupon. If they do, you could pay $3,188.66.

Does Medicare cover Xgeva and how much does it cost?

Xgeva may be covered under Medicare Part D and Medicare Advantage prescription drug plans; however, it is usually covered under Medicare Part B as a medical benefit. If you don't have Medicare coverage, ask the clinic or hospital where you receive Xgeva injections if they will accept a SingleCare Xgeva coupon. With SingleCare, you might pay $3,188.66.

Is there a generic of Xgeva?

Xgeva is a brand-name prescription drug that contains the active ingredient, denosumab. Generic denosumab is not available at this time.

What is Xgeva?

Xgeva is a brand-name prescription drug used to prevent bone loss in patients with multiple myeloma, giant cell tumor of bone, or other cancers that may cause bone loss. Multiple myeloma and giant bone cell tumors almost always involve bone loss. Xgeva can also be used to treat high blood levels of calcium (hypercalcemia) in people with cancer. 

Multiple myeloma is a cancer of the plasma cells, a type of white blood cell. Cancerous cells can gather in the bone marrow and become more abundant than healthy cells. Multiple myeloma cancer can increase the activity of osteoclasts, or bone cells responsible for breaking down bone , which can increase the release of calcium from the bone into the bloodstream. This can lead to high calcium levels and soft spots in the bones. The bones can gradually weaken and become more vulnerable to fractures.

Giant cell tumor of bone is a rare and benign tumor that forms at the ends of the long bones of the leg. Although the tumor is benign and almost never spreads to the rest of the body, it is locally aggressive and actively removes calcium from the bone around it.

High blood calcium due to cancer (hypercalcemia of malignancy) is a feature of many cancers and can have serious consequences. 

Xgeva, or denosumab, is a RANKL inhibitor. TWhen it is injected into the body, it attaches to a protein, called RANK ligand, that is found on certain bone cells that reabsorb calcium from the bones (osteoclasts). Denosumab, also considered a monoclonal antibody, targets RANKL and blocks its actions to prevent the breakdown of bone tissue and the release of excess calcium in the blood. 

Xgeva is usually administered as a subcutaneous (beneath the skin) injection once every four weeks.

What are the side effects of Xgeva?

Many people may experience injection site reactions, such as pain, redness, or irritation around the area of injection. In general, common side effects of Xgeva include, but are not limited to, headache, joint pain, back pain, muscle pain, diarrhea, nausea, weakness, and feeling tired. Serious side effects may include death of bone cells in the jaw (osteonecrosis of the jaw), unusual fractures of the femur, and low blood calcium levels (hypocalcemia), which could be life-threatening. Tell your physician if you notice worsening or persistent side effects. 

Xgeva is toxic to fetuses, so consult a healthcare provider before starting Xgeva if you are pregnant.

Allergic reactions are rare but can be severe. Signs and symptoms of an allergic reaction may include rash, swelling of the face or throat, and trouble breathing. 

This is not a complete list of possible side effects. Consult with your prescribing physician about other possible side effects of Xgeva and any other concerns you may have.