What is Furosemide: Uses, Warnings & Interactions

Updated Mar 19, 2024  •  Published Dec 30, 2020

Furosemide overview

BRAND NAMES:

  • Lasix, Furoscix, Disal (veterinary use), Salix (veterinary use)

Generic Names:

  • Furosemide

Uses:

  • Treats fluid retention (edema) and high blood pressure.

Therapeutic Classes:

  • Diuretic, loop diuretic

Forms:

  • Tablet, oral solution (liquid), injection

How it’s taken:

  • By mouth, intramuscular injection, intravenous injection

What is Furosemide used for?

Furosemide tablets and injections increase urination to help drain excess fluid (edema) due to heart failure, liver cirrhosis, or kidney disease. Furosemide also helps reduce high blood pressure. Furosemide injections are used to treat urgent medical crises that require rapid loss of water like fluid buildup in the lungs (pulmonary edema) or fluid overload due to heart failure.

What form(s) does Furosemide come in

  • Tablet

    • 20 mg

    • 40 mg

    • 80 mg

  • Oral solution (liquid)

    • 10 mg/mL

    • 40 mg/5 mL

  • Injection

    • 8 mg/mL

    • 10 mg/mL

What are common Furosemide doses?

  • For edema in adults: 40–120 mg taken by mouth once or twice per day OR 20–40 injection with additional doses once or twice per day as needed

  • For edema in children: 2 mg taken by mouth as a single dose followed by a second dose (2–4 mg/kg) as needed six to eight hours later OR 1 mg/kg injection followed by 2–6 mg/kg doses spaced at least 2 hours apart

  • For blood pressure in adults: 40 mg taken by mouth once per day 

  • For pulmonary edema in adults: 40 mg IV injection with a second 40–80 mg IV injection one hour later if needed

Common Furosemide prescriptions

  • Furosemide
    120ml of 10mg/ml bottle

  • Furosemide
    500ml of 8mg/ml bottle

  • Furosemide
    60ml of 10mg/ml bottle

  • Furosemide
    10ml of 10mg/ml syringe

  • Furosemide
    4ml of 10mg/ml syringe

  • Furosemide
    20mg tablet

  • Furosemide
    40mg tablet

  • Furosemide
    80mg tablet

  • Furosemide
    10ml of 10mg/ml vial

  • Furosemide
    2ml of 10mg/ml vial

  • Furosemide
    4ml of 10mg/ml vial

How to take Furosemide

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • The doctor may also instruct you to take dietary supplements such as potassium. Make sure to follow these directions. 

  • Furosemide can be taken with or without food.

    • You may take this medicine with food if it upsets your stomach.

  • How to take furosemide tablets

    • Swallow the tablet whole with a glass of water.

    • If swallowing the tablet is difficult, it can be crushed. Before doing this, ask the prescriber or the pharmacist if this is okay.

    • Store furosemide tablets at room temperature protected from moisture and light.

  • How to take furosemide oral solution

    • You do not need to shake the bottle before measuring out a dose.

    • Measure doses using a calibrated oral syringe or other device for measuring liquid medicine. Do not use kitchen utensils or tableware.

    • Discard any unused solution 90 days after the bottle has been opened.

    • Store this medicine at room temperature protected from light.

What to do if you miss a dose of Furosemide

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. 

  • Do not take extra medicine to make up for a missed dose.

Furosemide contraindications

  • This medicine is not right for everyone. 

  • Never use furosemide if you are not urinating at all (anuria).

  • Do not use it if you have had an allergic reaction to furosemide.

  • Furosemide cannot safely be given to people who are electrolyte-depleted until electrolyte levels are fixed.

  • Healthcare providers never use furosemide in people who are in a coma because of severe liver dysfunction.

Furosemide warnings

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine.

  • Your doctor will do lab tests regularly to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you are pregnant or breastfeeding.

  • Tell your doctor if you have:

    • Kidney disease

    • Liver disease (including cirrhosis)

    • Urinary retention including trouble urinating due to an enlarged prostate

    • Diabetes

    • Gout

    • Low blood pressure

    • Lupus

  • Tell your doctor if you’re allergic to sulfa drugs.

  • Tell your doctor if you are on a low-salt diet.

  • This medicine may cause the following problems: 

    • Electrolyte depletion, particularly low potassium or low sodium

    • Increased blood sugar levels

    • Hearing problems

  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

Furosemide interactions

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use before taking furosemide.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

  • If you are taking the stomach protectant sucralfate, take your furosemide dose at least two hours before or two hours after your sucralfate dose. 

  • Ethacrynic acid, another diuretic, should never be taken with furosemide.

  • Some medicines may cause problems when combined with furosemide. Tell your doctor if you are also taking: 

    • NSAIDs such as aspirin or ibuprofen

    • Blood pressure medications, particularly ACE inhibitors or angiotensin II receptor blockers (ARBs)

    • Corticosteroids such as prednisone

    • Thyroid medications

    • Aminoglycoside antibiotics

    • The heart failure drug digoxin

    • The cancer drug cisplatin

    • The immune suppressants cyclosporine or methotrexate

    • The seizure medication phenytoin

    • Lithium

    • Licorice supplements

  • Alcohol, narcotic pain medicine, or sleeping pills may cause dizziness, lightheadedness, or fainting when combined with furosemide.

  • People with high blood pressure should avoid medications that raise blood pressure including over-the-counter treatments for cold symptoms or weight loss. 

Furosemide side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Dry mouth, increased thirst, muscle cramps, uneven heartbeat

  • Confusion, weakness, muscle twitching

  • Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness

  • Severe diarrhea

  • Yellow skin or eyes

  • Unusual bleeding or bruising

  • Hearing loss, ringing in the ears

  • Lightheadedness, dizziness, fainting

  • Blistering, peeling, red skin rash, or other skin problems

  • Fever, fatigue, appetite loss, weight loss, aches and pains, red or purple bumps on the skin

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Increased urination

  • Dizziness

  • Loss of appetite

  • Nausea

  • Stomach cramps

Find more detailed information about furosemide side effects here.

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