Xiidra Coupons & Prices

Xiidra is a prescription eyedrop medication used to treat patients with signs and symptoms of dry eye syndrome, or dry eye disease (DED). Xiidra is a brand-name drug. The active ingredient in Xiidra is called lifitegrast. The way Xiidra works is not completely understood but it is thought to block a protein that causes dry eyes. The average Xiidra price is around $1,000.64 for 60, 5% Solution. However, you can use Xiidra coupons from SingleCare’s prescription discount plan to get a reduced price of $609.91 for 60, 5% Solution on your next prescription.

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Xiidra coupon at Kroger Pharmacy
$612.91
$ 609.91
  • How is this calculated?

  • Price if you don’t sign up:

    $612.91

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $609.91

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Xiidra coupon at Harris Teeter Pharmacy
$612.91
$ 609.91
  • How is this calculated?

  • Price if you don’t sign up:

    $612.91

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $609.91

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Xiidra coupon at Walgreens Pharmacy
$613.14
$ 610.14
  • How is this calculated?

  • Price if you don’t sign up:

    $613.14

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $610.14

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Xiidra coupon at Rite Aid Pharmacy
$629.76
$ 626.76
  • How is this calculated?

  • Price if you don’t sign up:

    $629.76

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $626.76

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Xiidra coupon at Cvs Pharmacy
$631.75
$ 628.75
  • How is this calculated?

  • Price if you don’t sign up:

    $631.75

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $628.75

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Xiidra coupon at Walmart Neighborhood Market Pharmacy
$665.65
$ 662.65
  • How is this calculated?

  • Price if you don’t sign up:

    $665.65

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $662.65

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$665.65
$ 662.65
  • How is this calculated?

  • Price if you don’t sign up:

    $665.65

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $662.65

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

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About

Xiidra is a prescription eyedrop medication used to treat patients with signs and symptoms of dry eye syndrome, or dry eye disease (DED). Xiidra is a brand-name drug. The active ingredient in Xiidra is called lifitegrast. The way Xiidra works is not completely understood but it is thought to block a protein that causes dry eyes. The average Xiidra price is around $1,000.64 for 60, 5% Solution. However, you can use Xiidra coupons from SingleCare’s prescription discount plan to get a reduced price of $609.91 for 60, 5% Solution on your next prescription.

Xiidra Price History & Information

Price History for Xiidra

60 count, 5%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Xiidra

60 count, 5%
PharmacyXiidra Retail PriceXiidra SingleCare Price
CVS Pharmacy$818.16$645.26
Walmart$810.05$641.90
Walgreens$1043.58$715.86
Kroger Pharmacy$825.93$599.67
Albertsons Pharmacy$748.45$647.77
Rite Aid Pharmacy$905.95$627.23

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

Xiidra FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Xiidra cost without insurance?

The retail price of a 30-day prescription of Xiidra without insurance is $1,000.64 for 60, 5% Solution. Try a free SingleCare savings card and pay a discounted price of $609.91 for 60, 5% Solution on your next Xiidra prescription.

How much does Xiidra cost with insurance?

The cost of Xiidra with health insurance may vary by insurance plan. Check with your pharmacist to determine your copay cost with your insurance when you order your Xiidra refill. With the SingleCare discount program, Xiidra may have a total cost of $609.91 for 60, 5% Solution for a one-month supply. This may work out to be cheaper than what your insurance company charges you. 

Ask the pharmacist at your local pharmacy to process SingleCare's coupons for Xiidra to compare prices today. Contact your insurance provider for more information and questions about your insurance coverage and costs. 

Does Medicare cover Xiidra and how much does it cost?

Medicare prescription plans may or may not cover Xiidra. The average copay for Xiidra with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out how much the Xiidra copay or coinsurance is. If your copay is high, another option is to ask the pharmacist at your participating pharmacy to run your SingleCare discount card at the time of service to compare payment options and get discounts on your prescription. Our lowest price for Xiidra is currently $609.91 for 60, 5% Solution.

How to save on Xiidra

People who are looking to save money on Xiidra can use a Xiidra coupon from SingleCare and pay $609.91 for 60, 5% Solution rather than $1,000.64 for 60, 5% Solution. Eligible patients include all Americans in the United States with a valid prescription. There are no other eligibility requirements, such as an application or membership fees. Unfortunately, although SingleCare is accepted at U.S. pharmacies, it is not accepted at international pharmacies in other countries such as the United Kingdom, Canada, Australia, India, Turkey, or New Zealand.

Is there a generic of Xiidra?

Xiidra is a brand-name prescription drug manufactured by Novartis Pharmaceuticals Corporation. Lifitegrast is the ingredient of this drug but there is currently no equivalent generic substitute of Xiidra available.

Who is the manufacturer of Xiidra? 

The pharmaceutical company that manufacturers Xiidra is called Novartis Pharmaceuticals Corporation. 

What is Xiidra?

Xiidra is an FDA-approved eye drop medication used to treat the symptoms of dry eye disease, sometimes referred to as dry eye syndrome. This prescription medication works by blocking certain proteins that can cause your eyes to not produce enough tears, resulting in dry eyes.

You should inform your doctor if you are pregnant or about to become pregnant as the effects of Xiidra on unborn and newborn babies have not yet been tested.

What class of drug is Xiidra? 

Xiidra is in a drug class called lymphocyte function-associated antigen-1 (LFA-1) antagonists and it is used to treat dry eye disease. 

What doses of Xiidra are available?

Xiidra is available in 60, 5% Solution, each containing a 5% ophthalmic solution. It should be used only as directed by your doctor or healthcare professional. Ensure that you wash your hands before and after using Xiidra. Do not use more of this medication than is recommended by your health care provider.

What are the side effects of Xiidra?

Common side effects of Xiidra may include changes in vision or vision problems including decreased visual acuity or blurred vision. 

Other common side effects may include instillation site irritation, change in taste or loss of taste, and redness of certain parts of your eyes. Some of these symptoms may not require medical attention and will go away as your body becomes accustomed to Xiidra. 

Serious side effects are rare, but if you experience symptoms of a serious allergic reaction such as hives, trouble breathing, or swelling of the face, lips, tongue, or throat, get emergency medical help. 

Individuals who are experiencing adverse effects over an extended period of time may need to seek medical care. Check with your doctor about these or any other possible side effects that you may be suffering from, as this is not a complete list of all adverse events.

Does Xiidra interact with other medications?

Before taking Xiidra, tell your physician about all of the medications you take, including prescription and over-the-counter medicines, vitamins, and supplements. Xiidra is not known to have any significant drug interactions. 

How do I store Xiidra?

Store Xiidra at room temperature, away from direct light, heat, and moisture. Keep out of the reach of children.

How do I use Xiidra?

Instill one drop in each eye twice daily, about 12 hours apart, using the single-use container. Discard the container after using in each eye. Remove contact lenses before using Xiidra and wait 15 minutes to put them back in after you put in your eye drops.

Who should not use Xiidra?

Xiidra should not be used in anyone who is allergic to lifitegrast or any inactive components of the medication. 

Is there an alternative to Xiidra?

Other prescription medications used for dry eye disease include Restasis (cyclosporine) or Cequa (cyclosporine). 

Eysuvis (loteprednol) is a prescription steroid eye drop that is used for short-term treatment of dry eyes. 

There are also various over-the-counter products that can help relieve symptoms of dry eyes, such as Artificial Tears or Systane. Consult your healthcare provider for professional medical advice and more information on dry eye treatment.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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