Epclusa Coupons & Prices

Epclusa is an antiviral prescription medication used to treat hepatitis C, which is an infection of the liver caused by a virus. The generic version of this drug is sofosbuvir-velpatasvir. The average retail price of Epclusa is about $34,622.34 for 1, 28 Tablets Bottle. Pay a lower cost of

0.5 Box28 tabletsEdit

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Epclusa coupon at Walgreens Pharmacy
$7793.21
$ 7,790
  • How is this calculated?

  • Price if you don’t sign up:

    $7793.21

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $7790.21

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Epclusa coupon at Cvs Pharmacy
$7978.00
$ 7,975
  • How is this calculated?

  • Price if you don’t sign up:

    $7978.00

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $7975.00

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Epclusa coupon at Kroger Pharmacy
$8096.39
$ 8,093
  • How is this calculated?

  • Price if you don’t sign up:

    $8096.39

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $8093.39

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Epclusa coupon at Harris Teeter Pharmacy
$8096.39
$ 8,093
  • How is this calculated?

  • Price if you don’t sign up:

    $8096.39

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $8093.39

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Epclusa coupon at Food Lion Pharmacy
$ 8,168
Epclusa coupon at Rite Aid Pharmacy
$8263.00
$ 8,260
  • How is this calculated?

  • Price if you don’t sign up:

    $8263.00

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $8260.00

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$8266.00
$ 8,263
  • How is this calculated?

  • Price if you don’t sign up:

    $8266.00

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $8263.00

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$8266.00
$ 8,263
  • How is this calculated?

  • Price if you don’t sign up:

    $8266.00

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $8263.00

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 8,839

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

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4.8 average rating
About Sofosbuvir-Velpatasvir

Epclusa is an antiviral prescription medication used to treat hepatitis C, which is an infection of the liver caused by a virus. The generic version of this drug is sofosbuvir-velpatasvir. The average retail price of Epclusa is about $34,622.34 for 1, 28 Tablets Bottle. Pay a lower cost of $7,790.21 for 1, 28 tablets Box by using SingleCare’s coupon program. This coupon can be redeemed for cash savings at participating local pharmacies.

Epclusa Price History & Information

Price History for Epclusa

1 count, 28 tablets

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Epclusa

1 count, 28 tablets
PharmacyEpclusa Retail PriceEpclusa SingleCare Price
CVS Pharmacy$16805.04$7978.04
Walmart$9710.12$8073.91
Walgreens$9488.92$8471.80
Kroger Pharmacy$9600.08$8096.37

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Epclusa

Epclusa is an antiviral prescription medication used to treat hepatitis C, which is an infection of the liver caused by a virus. The generic version of this drug is sofosbuvir-velpatasvir. The average retail price of Epclusa is about $34,622.34 for 1, 28 Tablets Bottle. Pay a lower cost of $7,790.21 for 1, 28 tablets Box by using SingleCare’s coupon program. This coupon can be redeemed for cash savings at participating local pharmacies.

Epclusa FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Epclusa cost without insurance?

Usually the cost of Epclusa, without insurance coverage, is around $34,622.34 for 1, 28 Tablets Bottle or sometimes more. SingleCare’s discount program can help you to save on this total with a Epclusa coupon. Pay just $7,790.21 for 1, 28 tablets Box for your Epclusa purchase when you use SingleCare’s Epclusa coupon at participating drugstores. You can access free SingleCare cards and coupons on our website or mobile app.

How much does Epclusa cost with insurance?

The cost of Epclusa with insurance may vary based on the type of health insurance plan that you are enrolled in. Contact your health plan directly to find out exactly how much Epclusa costs under your current insurance plan. SingleCare can help you to easily save on your Epclusa purchases. Pay only $7,790.21 for 1, 28 tablets Box for your Epclusa purchase when you use SingleCare’s Epclusa savings card.

Does Medicare cover Epclusa and how much does it cost?

Epclusa is covered by most Medicare Part D plans and Medicare Advantage plans. SingleCare can help to lower your out-of-pocket costs from Epclusa to $7,790.21 for 1, 28 tablets Box. Just use your SingleCare savings card at participating local pharmacies to claim these savings. 

Is there a generic of Epclusa?

Epclusa is a brand-name prescription drug manufactured by Gilead Sciences Inc. The generic version of this drug is sofosbuvir-velpatasvir.

What is Epclusa?

Epclusa is an FDA-approved prescription medication used to treat hepatitis C, which is an infection of the liver caused by a virus. This medication works by reducing the amount of hepatitis C virus in your body. This helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring or liver cancer. 

Epclusa can be used in adults and children 3 years and older. Epclusa treats certain genotypes of hepatitis C. Your healthcare provider will order tests to make sure Epclusa is the appropriate treatment for you. 

Epclusa may also be used with ribavirin to treat scarring of the liver.

Epclusa is sometimes used in patients who also have HIV. However, Epclusa does not treat HIV or AIDS. 

Read the instructional leaflet and Medication Guide provided with this medication before you begin use. This medication comes in the form of an oral tablet that can be taken with or without food. It is also available as a pellet that comes in a packet and can be taken directly in the mouth or mixed with a spoonful of soft food, like pudding. The pellets should not be chewed.

Take your medication daily as directed. Continue using this medication until your full prescription is complete, even if your symptoms go away early. Stopping this medication too early may result in a return of your infection. Refill your prescription several days before you need it, so that you do not run out.

What should I tell my healthcare provider before taking Epclusa? 

Before taking Epclusa, tell your doctor about all of your medical conditions, especially if you:

  • Are breastfeeding

  • Are a hepatitis B virus carrier

  • Are immunocompromised

  • Have diabetes

  • Have both a hepatitis B and hepatitis C infection

Tell your doctor about any allergies to medications, and all of the medications you take, including prescription and over-the-counter drugs, vitamins, and supplements. Epclusa interacts with certain drugs, such as the antibiotic rifampin, the supplement St. John’s Wort, and the anticonvulsant Tegretol (carbamazepine). Epclusa also interacts with antacids. If you need to take an antacid, then use it at least four hours after using Epclusa. 

Other drug interactions may occur. Consult your healthcare provider for a full list of drug interactions. 

What are the side effects of Epclusa?

Epclusa may cause side effects such as nausea, diarrhea, headaches, tiredness, weakness, irritability, or difficulty sleeping. Talk to your doctor if you experience any of these effects and they persist or worsen. Many patients using this medication do not have serious side effects. 

Serious allergic reactions to this medication are usually rare. However, you should seek emergency medical attention if you begin to experience symptoms of a serious allergic reaction such as hives, trouble breathing, or swelling of the face, lips, tongue, or throat.

If you have previously had hepatitis B, it may come back or worsen. Call your healthcare professional if you have upper stomach pain, vomiting, appetite loss, or yellowing of the skin and whites of the eyes.

Talk to your doctor or healthcare provider for full medical advice on the risks and benefits involved with using Epclusa as this is not a complete list of side effects.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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