Sexually-transmitted diseases, or STDs, are infections spread through sexual contact, including vaginal sex, oral sex, and anal sex. Also called sexually transmitted infections (STIs), they include bacterial, viral, and parasitic infections.
Each type of STD differs from the others. Some may have no symptoms or only mild ones. Some types of STDs can develop into severe and potentially life-threatening diseases. Although some are curable, others are not. The most common symptoms of an STD include blisters, bumps, rashes, or sores around the genitals or pubic area, discharge from the urethra or vagina, itching, and painful urination. See a doctor if any STD symptoms arise. Even if there are no symptoms, get screened for STDs, especially if there’s a high risk of exposure
STDs are a common health condition that can affect anyone regardless of age, sex, race, or ethnicity.
Early signs of an STD include genital sores, rash, blisters, urethral or vaginal discharge, vaginal bleeding, painful urination, frequent urination, itching, and pain during sex.
Serious symptoms of an STD, such as high fever, bleeding, or severe pain, may require immediate medical attention.
STDs may be caused by bacteria, viruses, fungi, and parasites. You may be at risk for developing STD symptoms if you have multiple sexual partners or unprotected sex.
STDs usually require a medical diagnosis.
STDs generally require treatment. STD symptoms typically resolve with treatment, but the timeline will depend on the infection.
Treatment of STDs may include antibiotics or antiviral medications. Read more about HIV, syphilis, gonorrhea, chlamydia, HPV, and trichomoniasis treatments below.
An untreated STD could result in complications like cancer, brain infections, heart disease, liver damage, infertility, pregnancy problems, opportunistic infections, and death.
Use coupons for STD treatments like Penicillin v (penicillin), Zithromax (azithromycin), Rocephin (ceftriaxone), Flagyl (metronidazole), and Zovirax (acyclovir) to save up to 80%.
The early signs of an STD will vary by infection. In many cases, an STD may not show any symptoms. In general, however, symptoms appear within one to four weeks of an infection, although the timeline of symptoms will depend on the type of STD.
Early signs of an STD may include:
The appearance of bumps, rash, blisters, growths, or open sores on the genitals, scrotum, pubic area, anus, rectum, or the area between the anus and the genitals
Painful or frequent urination
Itching
Discharge from the penis or vagina
Abnormal vaginal bleeding
Pelvic pain
Testicular pain
Flu-like symptoms
These early symptoms do not always indicate an STD. However, they are signs to get STD testing, particularly in people who engage in high-risk sexual activities, have multiple sex partners, or have unprotected sex.
STD symptoms will vary by the disease. Some infections are concentrated in the genital area and genital tract, but other infections may affect other parts of the body.
Chlamydia, a bacterial infection, is the most common and widely-spread STD. Chlamydia often does not cause symptoms in men and women. When symptoms do appear, the most common are:
Painful urination
Vaginal bleeding
Discharge from the vagina or penis
Itching
Gonorrhea is a bacterial infection that is the second most common STD. It is spread mainly through sexual contact and bodily fluids. Most people are asymptomatic and might not discover they’re infected until they’re tested, or they develop severe complications. When people do have noticeable symptoms, the most common are:
Vaginal or penile discharge
Painful urination
Pelvic pain
Pain in the testicles
Syphilis is a bacterial infection that is primarily spread through skin-to-skin contact during sex. The infection has four stages, including a latent stage in which the infection remains dormant in the body. However, not everyone who is infected will go through all stages. The most common symptoms of syphilis can vary depending on the stage of the disease and may include:
Painless sores on the genitals, anus, or mouth
Rash around the mouth, genitals, or anus
Fever
Swollen lymph nodes
Joint pain
Feeling sick
Loss of coordination
Nerve pain
Seizures
Visual changes
Hearing loss
Cognitive decline
Dementia
Genital herpes is a common and contagious viral infection that can affect the genitals, buttocks, anus, and upper thighs. It’s caused by the herpes simplex virus. Many people have no symptoms or very mild symptoms, so they don’t know that they are carrying and spreading the virus. When symptoms appear, the most common are:
Small, clear blisters on the genitals, pubic area, buttocks, anus, or inner thighs
Itching, tingling, or burning
Fever
Swollen lymph nodes
Pain during urination
HPV is another common and widespread STD that may cause no symptoms. HPV is a viral infection that is typically spread by skin-to-skin contact. Most infections are temporary and have mild symptoms. Some types of HPV can infect mucus membranes and are spread only by sexual contact. Although the infection clears on its own in most people, some types of HPV are chronic. It may also lead to cancer; more than 95% of cases of cervical cancer are caused by HPV. The most common symptom of HPV is genital warts that can appear uneven or rough.
Trichomoniasis is a common parasitic infection that is spread through sexual contact. In women, trichomoniasis typically causes symptoms in and around the vagina. In men, the parasite infects the urinary tract but usually has no symptoms. The most common symptoms of trichomoniasis are:
Vaginal discharge
Vaginal itching
Vaginal odor
Urethral discharge
Painful urination
Pain during intercourse
Human immunodeficiency virus (HIV) is a virus that attacks the immune system, specifically the CD4 cells, which assist the body in fighting off infections and diseases. It is often spread through sexual contact and blood-to-blood contact. The initial infection usually has flu-like symptoms. As the disease progresses, it compromises the body’s ability to fight off infections, causing a medical condition called acquired immune deficiency syndrome (AIDS). People with AIDS are prone to opportunistic infections and certain types of cancer, such as Kaposi’s sarcoma.
Viral hepatitis is a viral infection of the liver. There are three major types, all of which can be spread through sexual contact. Hepatitis A is typically spread through contaminated food or water. Hepatitis B and C are mainly transmitted through direct contact with infected body fluids, such as blood, semen, or vaginal secretions. The most common symptoms of an acute hepatitis infection are:
Fever
Fatigue
Abdominal pain
Vomiting
Dark urine
Loss of appetite
Pale or clay-colored stools
Jaundice (yellowing of the skin and eyes)
Both pubic lice (“crabs”) and scabies are tiny parasitic insects that infest the pubic area or other parts of the body. Although they are not viruses or bacteria that cause infections, pubic lice and scabies are often lumped into the category of STDs because they are typically spread through sexual contact. Infestations are common (about 3 million people a year in the U.S. get pubic lice), but they are not a health threat. They can be treated with a special lotion or shampoo. The most common symptoms are itching, redness, and rash around the genital area.
Don’t be confused by the terms sexually transmitted disease (STD) and sexually transmitted infections (STI). The difference is technical, and most people use the terms interchangeably. A sexually transmitted infection is any infection primarily spread through sexual contact. A sexually transmitted disease is any sexually transmitted infection that causes symptoms or other problems. In essence, all STDs start as STIs, but not all STIs progress to become STDs.
Why is this relevant? Many sexually-transmitted infections like gonorrhea or chlamydia don’t cause symptoms or any other problems in the body for a long time if ever. But they are contagious. Therefore, the main goal of treating STIs is not only to manage the potential symptoms but to prevent their spread to other people.
See a doctor when experiencing any STD symptoms. Even if the symptoms are mild, STDs can be spread to sexual partners. Many sexually-transmitted infections are symptomless but highly contagious. Some STDs have potentially serious or life-threatening complications.
People at risk for STDs should see a healthcare provider for screening, even if there are no signs of an STD. Healthcare professionals may diagnose STDs based on symptoms, a complete medical history, blood tests, and urine tests.
STDs can cause complications even if there are no symptoms. The most common complications are:
Pelvic inflammatory disease
Cervical, anal, and other types of cancer
HIV/AIDS
Orchitis (inflammation of the testicles)
Epididymitis (inflammation of the tube at the back of the testicle that stores and carries sperm)
Proctitis (inflammation of the rectum)
Pharyngitis (inflammation of the throat)
Chronic hepatitis
Liver cancer
Heart disease
Cognitive impairment
Mental health problems such as depression or anxiety
Increased risk of contracting other STDs
Infertility
Ectopic pregnancy
Complications during pregnancy and delivery, including neonatal herpes, premature labor, stillbirth, and low birth weight
Infection in newborns
Even if there are no symptoms, STDs should be diagnosed and treated by a healthcare professional. Like most infections, STDs are treated with prescription medications.
Bacterial infections and trichomoniasis are treated with antibiotics.
Herpes, hepatitis, and HIV may be treated with antiviral medications that can help manage the disease.
HPV does not have a specific treatment for the virus. However, there are treatments for the health problems it may cause. For instance, genital warts caused by HPV can be treated with prescription topical medications or removed surgically.
Bacterial STDs usually clear up with treatment, but viral STDs can be controlled but not cured. The infection could be lifelong, so take a few measures to stay healthy and prevent transmission:
Learn as much as you can about the infection and how to care for yourself
Take medications exactly as directed by a healthcare professional
Tell your intimate partner or partners about your infection
If they haven’t already, encourage your partner or partners to get STD testing
Use condoms and other physically protective contraception to avoid spreading the infection
The most important STD symptom people need to memorize is this one: no symptoms at all. Many types of STDs are asymptomatic, or they have such mild symptoms that people don’t notice them. Having no symptoms doesn’t mean a person has dodged an infection. Anyone engaging in high-risk sexual activity should seek regular STD testing. Getting treatment early after being tested can help ensure the best outcome, even for more severe STDs like HIV or syphilis. Just as importantly, early treatment prevents the spread of the infection.
The most common types of STDs are chlamydia, gonorrhea, syphilis, genital herpes, HPV, trichomoniasis, and HIV.
Bacterial STDs can usually be cured with antibiotics when treated early. A single course of antibiotics can often effectively treat many bacterial and parasitic STDs, including gonorrhea, syphilis, chlamydia, and trichomoniasis.
Viral STDs, such as HIV, HPV, and genital herpes, are difficult to treat and cannot be completely eradicated from the body. However, the disease progression can be controlled with antiviral medications. While there’s no cure for these diseases, vaccines may be available for the prevention of some, like HPV and hepatitis B.
Sexually transmitted diseases (STDs) fact sheets, Centers for Disease Control and Prevention (CDC)
What are sexually transmitted infections (STIs) or diseases (STDs), Urology Care Foundation-American Urological Foundation
Sexually transmitted diseases treatment guidelines, 2021, Centers for Disease Control and Prevention (CDC)
Extragenital infections caused by Chlamydia trachomatis Neisseria gonorrhoeae: a review of the literature, Infectious Diseases in Obstetrics and Gynecology
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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