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What is Tirosint-Sol: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Tirosint-Sol overview

BRAND NAMES:

  • Tirosint-Sol, Synthroid, Unithroid, Euthyrox, Levoxyl, Tirosint

Generic Names:

  • Tirosint-Sol

Uses:

  • Treats hypothyroidism, an enlarged thyroid gland, and thyroid cancer.

Therapeutic Classes:

  • Diagnostic Agent, Thyroid Function, Endocrine-Metabolic Agent, Thyroid Supplement

Forms:

  • Capsule, Liquid, Tablet

How it’s taken:

  • By mouth

What form(s) does Tirosint-Sol come in

  • Capsule

  • Liquid

  • Tablet

What are common Tirosint-Sol doses?

  • Plas Cont 1ML of 13MCG/ML

  • Plas Cont 1ML of 25MCG/ML

  • Plas Cont 1ML of 50MCG/ML

  • Plas Cont 1ML of 75MCG/ML

  • Plas Cont 1ML of 88MCG/ML

  • Plas Cont 1ML of 100MCG/ML

  • Plas Cont 1ML of 112MCG/ML

  • Plas Cont 1ML of 125MCG/ML

  • Plas Cont 1ML of 137MCG/ML

  • Plas Cont 1ML of 150MCG/ML

  • Plas Cont 1ML of 175MCG/ML

  • Plas Cont 1ML of 200MCG/ML

Common Tirosint-Sol prescriptions

  • Tirosint-SOL
    1ml ampule of 37.5mcg/ml 1 pouch of 5 ampules (5ml)

  • Tirosint-SOL
    1ml ampule of 44mcg/ml 1 pouch of 5 ampules (5ml)

  • Tirosint-SOL
    1ml ampule of 62.5mcg/ml 1 pouch of 5 ampules (5ml)

  • Tirosint-SOL
    1ml ampule of 137mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 150mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 200mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 25mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 37.5mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 44mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 50mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 62.5mcg/ml 6 pouches of 5 ampules (30ml box)

  • Tirosint-SOL
    1ml ampule of 88mcg/ml 6 pouches of 5 ampules (30ml box)

How to take Tirosint-Sol

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. You may have to take this medicine for 4 to 8 weeks before your symptoms start to get better.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take this medicine in the morning on an empty stomach, at least 30 to 60 minutes before eating breakfast.

  • Capsule: Swallow whole. Do not cut, chew, or crush it.

  • Oral liquid: This medicine may be mixed with water or be given directly into the mouth.If mixed with water: Squeeze the contents of 1 single unit-dose ampule into a glass or cup containing water. Stir and drink it right away. Add some water to the glass or cup and drink the water. This will help get all of the medicine out of the glass or cup. Do not mix this medicine with any other liquid except water. Do not store the mixture for later use.If taken without water: Squeeze the medicine directly into the mouth or into a spoon and swallow it right away.

  • Tablet: If you are giving this medicine to a baby or child who cannot swallow the tablet whole, crush the tablet and mix it in 1 to 2 teaspoons (5 to 10 milliliters) of water. Give the mixture right away using a spoon or dropper. Do not mix the tablet with any other liquid except water. Do not store the mixture for future use.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.

  • Take this medicine in the morning on an empty stomach, at least 30 to 60 minutes before eating breakfast.

  • Tablet: If you are giving this medicine to a baby or child who cannot swallow the tablet whole, crush the tablet and mix it in 1 to 2 teaspoons (5 to 10 milliliters) of water. Give the mixture right away using a spoon or dropper. Do not mix the tablet with any other liquid except water. Do not store the mixture for future use.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. You may have to take this medicine for 4 to 8 weeks before your symptoms start to get better.

  • Capsule: Swallow whole. Do not cut, chew, or crush it.

  • Oral liquid: This medicine may be mixed with water or be given directly into the mouth.If mixed with water: Squeeze the contents of 1 single unit-dose ampule into a glass or cup containing water. Stir and drink it right away. Add some water to the glass or cup and drink the water. This will help get all of the medicine out of the glass or cup. Do not mix this medicine with any other liquid except water. Do not store the mixture for later use.If taken without water: Squeeze the medicine directly into the mouth or into a spoon and swallow it right away.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.

Tirosint-Sol contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to levothyroxine or glycerol, or if you have an uncorrected adrenal gland problem or a recent heart attack.

Tirosint-Sol warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, anemia, blood clotting problems, diabetes, osteoporosis, pituitary gland problems, or adrenal gland problems. Tell your doctor if you have recently received radiation treatment with iodine.

  • This medicine may cause the following problems:Heart problems, including angina (chest pain), heart rhythm problemsMyxedema coma, which may be life-threateningLow bone density

  • This medicine should not be used to treat obesity or as part of a treatment plan for a weight control program.

  • Tell any doctor or dentist who treats you that you are taking this medicine.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Tirosint-Sol interactions

  • Some foods and medicines can affect how levothyroxine works. Tell your doctor if you are using any of the following:Amiodarone, asparaginase, carbamazepine, clofibrate, dexamethasone, digoxin, 5-fluorouracil, furosemide, heroin, imatinib, ketamine, methadone, mitotane, nicotinic acid, phenobarbital, phenytoin, rifampin, tamoxifenBeta-blocker medicineBirth control pills (including estrogen)Blood thinner (including heparin, warfarin)Insulin or diabetes medicineMedicine to treat depression (including amitriptyline, maprotiline)NSAIDsSalicylatesSteroids (including dexamethasone, androgens, anabolic steroids)

  • If you are using kayexalate, lanthanum, orlistat, sevelamer, sucralfate, antacids (including aluminum or magnesium hydroxide, simethicone), medicine to lower cholesterol (including cholestyramine, colesevelam, colestipol), stomach medicine (including lansoprazole, omeprazole, pantoprazole), or any medicine that contains calcium or iron, take them at least 4 hours before or 4 hours after you take levothyroxine.

  • Cottonseed meal, dietary fiber, soybean flour (infant formula), or walnuts may decrease the absorption of this medicine. Talk with your doctor if you have questions.

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tirosint-Sol side effects

Serious Side Effects

  • Seizures or tremors

  • Fast, pounding, or uneven heartbeat

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain that may spread, trouble breathing, unusual sweating, fainting

  • Confusion, swelling of the face, tongue, or lower legs, feeling cold, unusual tiredness or weakness

  • Dizziness, lightheadedness, stomach pain

  • Walking with a limp, knee or hip pain (in children)

  • Severe headache, blurred or double vision, nausea, vomiting (in children)

Less Serious Side Effects

  • Hair loss

  • Appetite or weight changes

  • Diarrhea

  • Changes in your menstrual periods

  • Muscle spasm or weakness

  • Trouble sleeping

  • Nervousness, sensitivity to heat

Tirosint-Sol News & Research

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