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What is Metoprolol-Hydrochlorothiazide: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Metoprolol-Hydrochlorothiazide overview

BRAND NAMES:

  • Dutoprol, Lopressor HCT

Generic Names:

  • Metoprolol-Hydrochlorothiazide

Uses:

  • Treats high blood pressure. This medicine is a combination of a beta-blocker and a diuretic (water pill).

Therapeutic Classes:

  • Beta-Adrenergic Blocker, Cardioselective/Thiazide Combination, Beta-Adrenergic Blocker/Thiazide Combination

Forms:

  • Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What is Metoprolol-Hydrochlorothiazide used for?

Lopressor HCT is a beta blocker that is used in the treatment of high blood pressure. It works by keeping certain natural chemicals such as epinephrine from acting on the heart and blood vessels.

What form(s) does Metoprolol-Hydrochlorothiazide come in

  • Tablet

  • Long Acting Tablet

What are common Metoprolol-Hydrochlorothiazide doses?

  • Tablet 50-25MG

  • Tablet 100-25MG

  • Tablet 100-50MG

Common Metoprolol-Hydrochlorothiazide prescriptions

  • Metoprolol-hydroCHLOROthiazide
    100-25mg tablet

  • Metoprolol-hydroCHLOROthiazide
    100-50mg tablet

  • Metoprolol-hydroCHLOROthiazide
    50-25mg tablet

How to take Metoprolol-Hydrochlorothiazide

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Tablet: Take it with a meal or just after a meal.

  • Extended-release tablet: Take it with or without food. Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Missed dose: If you miss a dose or forget to use your medicine, skip the missed dose. Never take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Extended-release tablet: Take it with or without food. Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Tablet: Take it with a meal or just after a meal.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: If you miss a dose or forget to use your medicine, skip the missed dose. Never take extra medicine to make up for a missed dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Metoprolol-Hydrochlorothiazide contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to metoprolol, hydrochlorothiazide, or sulfa drugs, if you cannot pass urine, or if you have certain blood circulation or heart problems. Ask your doctor about these problems..

Metoprolol-Hydrochlorothiazide warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, heart rhythm problems (including bradycardia), glaucoma, gout, diabetes, lupus, an overactive thyroid, pheochromocytoma, trouble urinating, or a history of asthma or lung disease.

  • This medicine may cause the following problems:New or worsening heart failureEye or vision problems, including glaucoma, myopiaIncreased risk for skin cancer

  • Do not stop using this medicine suddenly without asking your doctor, or you could develop life-threatening heart problems.

  • Tell any doctor or dentist who treats you that you are using this medicine, especially before you have any type of surgery.

  • This medicine may cause you to feel dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you are dizzy or lightheaded.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Slow, fast, pounding, or uneven heartbeat

  • Sudden and severe stomach pain, nausea, or vomiting

  • Swelling in your hands, feet, ankles, or legs, tiredness

  • Trouble breathing or wheezing

Metoprolol-Hydrochlorothiazide interactions

  • Some foods and medicines can affect how metoprolol/hydrochlorothiazide works. Tell your doctor if you use the following:Cholestyramine, cimetidine, clonidine, colestipol, digoxin, diphenhydramine, fluoxetine, hydroxychloroquine, lithium, methyldopa, paroxetine, propafenone, quinidine, reserpine, ritonavir, terbinafine, thioridazineInsulin or diabetes medicineMAO inhibitor (MAOI)NSAIDs (including aspirin, diclofenac, indomethacin, naproxen)Steroid medicine

  • Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.

  • Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used together with this medicine.

  • Tell any doctor or dentist who treats you that you are using this medicine, especially before you have any type of surgery.

  • This medicine may cause you to feel dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you are dizzy or lightheaded.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Metoprolol-Hydrochlorothiazide side effects

Serious Side Effects

  • Slow, fast, pounding, or uneven heartbeat

  • Swelling in your hands, feet, ankles, or legs, tiredness

  • Lightheadedness, dizziness, or fainting

  • Sudden and severe stomach pain, nausea, or vomiting

  • Confusion, weakness, and muscle twitching

  • Sores, reddish patch or irritated area, shiny bump, pink growth, or white, yellow or waxy scar-like area on the skin

  • Chest pain that may spread, unusual sweating, fainting

  • Eye pain, vision changes, seeing halos around lights

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Dry mouth, increased thirst, or muscle cramps

  • Change in how much or how often you urinate

Less Serious Side Effects

  • Diarrhea, constipation, loss of appetite, or stomach upset

  • Depression

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