Make saving on Rx even easier

Get the Free SingleCare app

(23,450)
Open app
Close Menu
Hello
Explore

What is Avalide: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Avalide overview

BRAND NAMES:

  • Avalide

Generic Names:

  • Irbesartan-Hydrochlorothiazide

Uses:

  • Treats high blood pressure. This medicine contains an angiotensin receptor blocker (ARB) and a diuretic (water pill).

Therapeutic Classes:

  • Angiotensin II Receptor Antagonist/Thiazide Combination

Forms:

  • Tablet

How it’s taken:

  • By mouth

What form(s) does Avalide come in

  • Tablet

What are common Avalide doses?

  • Tablet 300-12.5MG

  • Tablet 150-12.5MG

Common Avalide prescriptions

  • Avalide
    90 tablets bottle

  • Avalide
    150-12.5mg tablet

  • Avalide
    300-12.5mg tablet

How to take Avalide

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Swallow the tablet whole. Do not break, crush, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Swallow the tablet whole. Do not break, crush, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Avalide contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to irbesartan, hydrochlorothiazide, or a sulfa drug, or if you are pregnant or not able to urinate.

Avalide warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine is not safe to take during pregnancy, especially in your second or third trimester. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you are breastfeeding, or if you have kidney problems, liver disease, heart failure, diabetes, gout, high cholesterol, or lupus. Tell your doctor if you have a history of asthma or allergies.

  • This medicine may cause the following problems:Kidney problemsEye or vision problems, including glaucoma, myopiaChanges in blood sugar levelsIncreased risk of skin cancer

  • This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. This is more likely to happen when you first use the medicine or if you become dehydrated. Stand or sit up slowly if you are dizzy.

  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.

  • Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting while you are using this medicine.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Avalide interactions

  • Do not use this medicine together with aliskiren if you have diabetes.

  • Some medicines can affect how irbesartan/hydrochlorothiazide works. Tell your doctor if you are using any of the following:Aliskiren, carbamazepine, cholestyramine, colestipol, lithiumOther blood pressure medicine, including ACE inhibitorsInsulin or oral diabetes medicineMuscle relaxantsNSAIDs (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Steroid medicine

  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

  • Alcohol, narcotic pain medicine, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.

  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Avalide side effects

Serious Side Effects

  • Vision changes or eye pain

  • Sores, reddish patch or irritated area, shiny bump, pink growth, or white, yellow or waxy scar-like area on the skin

  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat

  • Lightheadedness, dizziness, fainting

  • Confusion, weakness, muscle twitching

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Decrease in how much or how often you urinate

Less Serious Side Effects

  • Muscle or joint pain

  • Tiredness

Avalide News & Research

Drug Info

Lisinopril interactions to avoid

Nov 30, 2023  by Karen Berger, Pharm.D.
Lisinopril interacts with diuretics, ARBs, NSAIDs, insulin, and ARBs. Here’s what you should not take with lisinopril to avoid side effects.
...
Drug Info

Propranolol Hcl (Inderal) alternatives: What can I take instead of propranolol?

Sep 7, 2023  by Chad Shaffer, MD
Inderal LA, Toprol XL, Coreg, Cardizem CD, and Nurtec are some propranolol alternatives. Get the full list here, including natural alternatives for hypertension management.
...
Drug Info

Edarbyclor alternatives: What can I take instead of edarbyclor?

Oct 13, 2022  by Chad Shaffer, MD
Diovan HCT, Norvasc, Exforge, Exforge HCT, and Toprol XL are some Edarbyclor alternatives. Get the full list here, including natural high blood pressure remedies.
...
Drug Info

Clonidine alternatives: What can I take instead of clonidine?

Oct 11, 2022  by Chad Shaffer, MD
Diovan, hydrochlorothiazide, Norvasc, Toprol XL, and Intuniv are some clonidine alternatives. Get the full list here, including natural high blood pressure remedies.
...
Drug Info

Hydrochlorothiazide alternatives: What can I take instead of hydrochlorothiazide?

Sep 16, 2022  by Chad Shaffer, MD
Zestril, Diovan, Norvasc, Lasix, and Aldactone are some hydrochlorothiazide alternatives. Get the full list here, including natural diuretics.
...
Drug Info

Cozaar (losartan) alternatives: What can I take instead of losartan?

Jun 2, 2022  by Stephanie Melby, Pharm.D.
Valsartan, lisinopril, losartan/hydrochlorothiazide, amlodipine, and chlorthalidone are some Cozaar (losartan) alternatives. Get the full list here, including natural ARBs.
...
Drug Info

Lisinopril alternatives: What can I take instead of lisinopril?

Mar 31, 2022  by Chad Shaffer, MD
Lotensin, Diovan, hydrochlorothiazide, Norvasc, and Toprol XL are some lisinopril alternatives. Get the full list here, including natural blood pressure remedies.
...
Drug Info

Bystolic alternatives: What can I take instead of Bystolic?

Mar 28, 2022  by Chad Shaffer, MD
Toprol XL, Lotensin, Diovan, hydrochlorothiazide, and Norvasc are some Bystolic alternatives. Get the full list here, including natural remedies to lower blood pressure.
...
Drug Info

What are thiazide diuretics?

Jun 19, 2021  by Keith Gardner, R.Ph.
Thiazide diuretics are a type of diuretic. They work by reducing fluid and widening blood vessels. Learn more about thiazide diuretics uses and safety here.
...