What is Trandolapril-Verapamil Hcl Er: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Trandolapril-Verapamil Hcl Er overview

BRAND NAMES:

  • Tarka

Generic Names:

  • Trandolapril-Verapamil Hcl Er

Uses:

  • Treats high blood pressure. This medicine contains an ACE inhibitor and a calcium channel blocker (CCB).

Therapeutic Classes:

  • ACE Inhibitor/Calcium Channel Blocker Combination

Forms:

  • Long Acting Tablet

How it’s taken:

  • By mouth

What form(s) does Trandolapril-Verapamil Hcl Er come in

  • Long Acting Tablet

What are common Trandolapril-Verapamil Hcl Er doses?

  • Tablet 4mg/240mg

  • Tablet 2mg/240mg

  • Tablet 2mg/180mg

  • Tablet 1mg/240mg

Common Trandolapril-Verapamil Hcl Er prescriptions

  • Trandolapril-Verapamil HCl ER
    1mg/240mg tablet

  • Trandolapril-Verapamil HCl ER
    2mg/180mg tablet

  • Trandolapril-Verapamil HCl ER
    2mg/240mg tablet

  • Trandolapril-Verapamil HCl ER
    4mg/240mg tablet

  • Trandolapril-Verapamil HCl ER
    1-240mg tablet extended release

How to take Trandolapril-Verapamil Hcl Er

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Oral routeIt is best to take this medicine with food or milk.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Oral routeIt is best to take this medicine with food or milk.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

Trandolapril-Verapamil Hcl Er contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to verapamil, trandolapril, or another ACE inhibitor, or you are pregnant or breastfeeding, or you have a history of angioedema caused by an ACE inhibitor.

Trandolapril-Verapamil Hcl Er warnings

  • This medicine may cause the following problems:Heart problems (including heart failure, changes in heart rhythm)Low blood pressureLiver problemsAngioedema (severe swelling)Kidney problems

  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you are dizzy or lightheaded.

  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.

  • Tell any doctor or dentist who treats you that you are using this medicine.

  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you have kidney problems, liver disease, diabetes, heart failure, heart disease, heart rhythm problems (including PR interval prolongation), or an autoimmune disorder (including lupus or scleroderma).

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trandolapril-Verapamil Hcl Er interactions

  • Do not use this medicine together with aliskiren if you have diabetes.

  • Do not use this medicine together with sacubitril. Do not use this medicine and sacubitril/valsartan within 36 hours of each other.

  • Do not use this medicine at least 2 weeks before or 2 days after using flibanserin.

  • Some medicines can affect how trandolapril/verapamil works. Tell your doctor if you are using any of the following:Colchicine, cyclosporine, digitalis, digoxin, doxorubicin, everolimus, gold injection, ivabradine, lithium, ritonavir, sirolimus, St John's wort, sulfinpyrazone, tacrolimus, temsirolimus, or theophyllineAnother blood pressure medicine, including an angiotensin receptor blocker (ARB) or a beta-blockerDiuretic (water pill, including amiloride, spironolactone, triamterene)Insulin or oral diabetes medicine (including glyburide)Medicine for heart rhythm problems (including disopyramide, flecainide, quinidine)Medicine to lower cholesterol (including atorvastatin, lovastatin, simvastatin)Medicine to treat depression or sedatives (including almotriptan, buspirone, imipramine, midazolam)Medicine to treat infection (including clarithromycin, erythromycin, rifampin, telithromycin)Medicine to treat seizures (including carbamazepine, phenobarbital)NitratesNSAID pain medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)

  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

  • Tell any doctor or dentist who treats you that you are using this medicine.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trandolapril-Verapamil Hcl Er side effects

Serious Side Effects

  • Change in how much or how often you urinate

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Lightheadedness, dizziness, fainting

  • Chest pain that may spread, trouble breathing, unusual sweating, fainting

  • Fast, pounding, or uneven heartbeat

  • Confusion, weakness, uneven heartbeat, numbness or tingling in your hands, feet, or lips

  • Fever, chills, sore throat, body aches

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Dry cough

  • Headache