Xifaxan is a prescription antibiotic used to treat traveler’s diarrhea due to E. coli, irritable bowel syndrome with diarrhea, and hepatic encephalopathy. It is a brand-name antibiotic that is available under the generic name rifaximin. The typical Xifaxan cost is $403.66 for 6, 550MG Tablet, but you could pay as little as $319.32 for 6, 550mg Tablet with a SingleCare coupon. You can use Xifaxan coupons from SingleCare to save on the retail price of Xifaxan at participating pharmacies.
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How is this calculated?
Price if you don’t sign up:
$322.32
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$319.32
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
How is this calculated?
Price if you don’t sign up:
$325.84
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$322.84
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
How is this calculated?
Price if you don’t sign up:
$325.84
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$322.84
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
How is this calculated?
Price if you don’t sign up:
$328.38
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$325.38
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
How is this calculated?
Price if you don’t sign up:
$328.38
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$325.38
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
How is this calculated?
Price if you don’t sign up:
$328.78
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$325.78
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
How is this calculated?
Price if you don’t sign up:
$337.54
One-time sign-up bonus:
-$3.00
Price with free sign-up:
$334.54
Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.
Xifaxan is a prescription antibiotic used to treat traveler’s diarrhea due to E. coli, irritable bowel syndrome with diarrhea, and hepatic encephalopathy. It is a brand-name antibiotic that is available under the generic name rifaximin. The typical Xifaxan cost is $403.66 for 6, 550MG Tablet, but you could pay as little as $319.32 for 6, 550mg Tablet with a SingleCare coupon. You can use Xifaxan coupons from SingleCare to save on the retail price of Xifaxan at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Pharmacy | Xifaxan Retail Price | Xifaxan SingleCare Price |
---|---|---|
CVS Pharmacy | $389.92 | $316.32 |
Walmart | $384.34 | $329.51 |
Walgreens | $384.34 | $334.85 |
Kroger Pharmacy | $382.20 | $318.50 |
Albertsons Pharmacy | $355.26 | $327.99 |
Rite Aid Pharmacy | $451.80 | $326.42 |
These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
People without insurance may pay an average price of $403.66 for Xifaxan. The price without insurance can vary depending on the pharmacy. Check with your local pharmacy to determine the total cost of your prescription without insurance. If you don’t have insurance, you can use a Xifaxan coupon from SingleCare to potentially reduce your out-of-pocket expenses to $319.32 for 6, 550MG Tablet.
The cost of Xifaxan with insurance depends on your insurance plan and your pharmacy. Xifaxan is typically covered by most insurance plans. However, you may still owe a copay or coinsurance amount. Check with your insurance company or pharmacist to determine the cost of your prescription.
Xifaxan is often covered by Medicare Part D and Medicare Advantage plans. The cost of Xifaxan with Medicare will depend on your plan’s formulary and the coverage stage you’re in. In some cases, you may have to pay a high out-of-pocket cost even with coverage. However, you may be able to save more on Xifaxan with a SingleCare savings card. Check with your local pharmacy to compare discounts and get maximum savings.
Salix Pharmaceuticals, the manufacturer of Xifaxan, currently offers a savings card for eligible patients who are covered with commercial insurance. The savings card may act as a manufacturer coupon to save on Xifaxan.
In addition, the Patient Access Network Foundation (PAN) and Bausch Health Patient Assistance Program provide Xifaxan patient assistance for eligible patients without insurance coverage. With patient assistance, patients could get Xifaxan for free or at a discounted rate. You can contact the manufacturer directly for more information on Xifaxan manufacturer coupons, rebates, or other potential savings options.
If you're ineligible for financial assistance, all patients qualify for SingleCare savings. You can sign up for free and potentially get a better price on your Xifaxan prescription at participating pharmacies.
Xifaxan is a brand-name prescription drug that's manufactured by Salix Pharmaceuticals. It contains the active ingredient rifaximin. There is currently no generic version of Xifaxan available on the market.
Xifaxan is classified as an antibiotic. It works by blocking the bacteria’s ability to produce certain proteins, which slows bacterial growth. Xifaxan is unique from other antibiotics because it travels through your stomach and into your intestines without getting absorbed into the blood. Xifaxan only works in the intestinal tract and will not work for infections in other areas of your body.
Xifaxan is FDA approved to treat traveler’s diarrhea caused by E. coli. It is also approved to treat irritable bowel syndrome with diarrhea (IBS-D) and hepatic encephalopathy, which is a decline in brain function associated with liver disease. Xifaxan should not be used for infections not caused by bacteria.
The recommended dosage of Xifaxan varies based on the condition that is being treated. You should only use Xifaxan in doses recommended by your doctor. Generally, for traveler’s diarrhea, one 200 mg tablet is taken three times a day for three days. For irritable bowel syndrome with diarrhea, one 550 mg tablet is taken three times a day for 14 days. For the treatment of hepatic encephalopathy, one 550 mg tablet is recommended twice daily.
The most common side effects of Xifaxan are headache, swelling in the legs and ankles (peripheral edema), nausea, fatigue, dizziness, and increased liver enzymes. Other side effects may include low red blood cell counts (anemia), excess abdominal fluid (ascites), muscle spasms, sore throat, and joint pain.
Serious side effects of Xifaxan may include Clostridium difficile-associated diarrhea, which is severe diarrhea with inflammation in the colon, and the development of an infection caused by resistant bacteria. Allergic reactions are also possible while taking Xifaxan. Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as hives, rash, swelling of the throat, or difficulty breathing.
This is not a complete list of side effects, warnings, and precautions. Consult a healthcare provider for medical advice and more information.
Stopping antibiotics like Xifaxan early may cause the bacteria to develop antibiotic resistance, which may lead to a more severe infection. Tell your doctor or healthcare provider if you experience diarrhea that lasts longer than a couple of days or is accompanied by fever or blood in the stool. It’s important to follow your doctor's instructions and complete the entire course of Xifaxan as prescribed, even if you start to feel better before finishing the treatment. If you have any concerns or questions about stopping Xifaxan, consult your healthcare provider for guidance.
Xifaxan is a strong antibiotic that targets bacteria in the intestines, making it effective for treating conditions like IBS-D, hepatic encephalopathy, and traveler's diarrhea. Its action is mainly localized to the gut, so it has minimal impact on other parts of the body. This reduces the risk of side effects and makes Xifaxan a more targeted treatment option for intestinal infections.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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* Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price.
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This is a prescription discount plan. This is NOT insurance nor a Medicare prescription drug plan. The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. You are fully responsible for paying your prescriptions at the pharmacy at the time of service, but you will be entitled to receive a discount from the pharmacy in accordance with the specific pre-negotiated discounted rate schedule. Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.Towers Administrators LLC (operating as 'SingleCare Administrators') is the authorized prescription discount plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services LLC ('SingleCare') is the vendor of the prescription discount plan, including their website.website at www.singlecare.com. For additional information, including an up-to-date list of pharmacies, or assistance with any problems related to this prescription drug discount plan, please contact customer service toll free at 844-234-3057, 24 hours a day, 7 days a week (except major holidays). By using the SingleCare prescription discount card or app, you agree to the SingleCare Terms and Conditions found at https://www.singlecare.com/terms-and-conditions
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