Otezla Coupons & Prices

Otezla is an oral prescription drug used to treat adults with moderate to severe plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's Disease. There is a generic version of Otezla available called aprelimast. On average, you could pay a retail price of $6,117.75
Pay as little as $0* out-of-pocket for Otezla (apremilast)
  • No matter your current financial situation, we are here to help YOU.

  • The Otezla Co-Pay Program is designed to help eligible patients with commercial insurance (usually self-purchased or through an employer) lower their out-of-pocket costs for Otezla.

*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.

Important Safety Information

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

The most common side effects of Otezla include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects.Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla.

APPROVED USES

Otezla ®  (apremilast) is a prescription medicine used to treat adult patients with:

  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

  • Active psoriatic arthritis. Oral ulcers associated with Behçet’s Disease.

6 Tablet30mgEdit

Pay as little as $0* out-of-pocket for Otezla (apremilast)
  • No matter your current financial situation, we are here to help YOU.

  • The Otezla Co-Pay Program is designed to help eligible patients with commercial insurance (usually self-purchased or through an employer) lower their out-of-pocket costs for Otezla.

*Eligibility criteria and program maximums apply. See AmgenSupportPlus.com/copay-terms for full Terms and Conditions.

Important Safety Information

You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla.

Otezla can cause allergic reactions, sometimes severe. Stop using Otezla and call your healthcare provider or seek emergency help right away if you develop any of the following symptoms of a serious allergic reaction: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of complications from having severe diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur.

Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.

Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.

Some medicines may make Otezla less effective and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.

The most common side effects of Otezla include diarrhea, nausea, upper respiratory tract infection, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects.Tell your doctor about any side effect that bothers you or does not go away.

Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Please click here for the Full Prescribing Information for Otezla.

APPROVED USES

Otezla ®  (apremilast) is a prescription medicine used to treat adult patients with:

  • Plaque psoriasis for whom phototherapy or systemic therapy is appropriate.

  • Active psoriatic arthritis. Oral ulcers associated with Behçet’s Disease.

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Otezla coupon at Walgreens Pharmacy
$4427.84
$ 4,425
  • How is this calculated?

  • Price if you don’t sign up:

    $4427.84

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4424.84

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Otezla coupon at Kroger Pharmacy
$4504.75
$ 4,502
  • How is this calculated?

  • Price if you don’t sign up:

    $4504.75

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4501.75

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Otezla coupon at Harris Teeter Pharmacy
$4504.75
$ 4,502
  • How is this calculated?

  • Price if you don’t sign up:

    $4504.75

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4501.75

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Otezla coupon at Cvs Pharmacy
$4545.15
$ 4,542
  • How is this calculated?

  • Price if you don’t sign up:

    $4545.15

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4542.15

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Otezla coupon at Rite Aid Pharmacy
$4606.33
$ 4,603
  • How is this calculated?

  • Price if you don’t sign up:

    $4606.33

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4603.33

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Otezla coupon at Walmart Neighborhood Market Pharmacy
$4719.05
$ 4,716
  • How is this calculated?

  • Price if you don’t sign up:

    $4719.05

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4716.05

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$4719.05
$ 4,716
  • How is this calculated?

  • Price if you don’t sign up:

    $4719.05

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4716.05

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 4,935
$ 5,340

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

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4.8 average rating
About Otezla

Otezla is an oral prescription drug used to treat adults with moderate to severe plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's Disease. There is a generic version of Otezla available called aprelimast. On average, you could pay a retail price of $6,117.75 for 60, 30MG Tablet. To save on Otezla costs, you may be able to use a free Otezla coupon from SingleCare, which is accepted at participating pharmacies nationwide.

Otezla Price History & Information

Price History for Otezla

60 count, 30mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Otezla

60 count, 30mg
PharmacyOtezla Retail PriceOtezla SingleCare Price
CVS Pharmacy$9693.15$4426.99
Walmart$5197.80$4455.78
Walgreens$5643.94$4919.66
Kroger Pharmacy$7383.75$4388.40
Albertsons Pharmacy$5052.80$4612.40
Rite Aid Pharmacy$6225.00$4487.70

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Otezla

Otezla is an oral prescription drug used to treat adults with moderate to severe plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's Disease. There is a generic version of Otezla available called aprelimast. On average, you could pay a retail price of $6,117.75 for 60, 30MG Tablet. To save on Otezla costs, you may be able to use a free Otezla coupon from SingleCare, which is accepted at participating pharmacies nationwide.

Otezla FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Otezla cost without insurance?

Without insurance, the average retail cost of Otezla is $6,117.75 for 60, 30MG Tablet. The cash price of Otezla can vary depending on the quantity purchased and the pharmacy location where it is purchased. Otezla can be an expensive prescription. Fortunately, SingleCare offers Otezla coupons to help save on the cash price of medications. You could pay only $4,424.84 for 60, 30mg Tablet at a participating pharmacy with a SingleCare card. You may need to purchase Otezla from a specialty pharmacy.

How much does Otezla cost with insurance?

Insurance copay costs for Otezla can vary by insurance plan, coverage stage, and quantity prescribed. Contact your health insurance company to determine your cost for Otezla with insurance coverage. You can also check your insurance plan’s formulary to see if they will cover Otezla. In some cases, SingleCare may offer better savings than your insurance plan. To determine the best payment option, ask your pharmacist to apply your SingleCare discount card and compare Otezla prices.

Does Medicare cover Otezla and how much does it cost?

Most Medicare prescription plans cover Otezla. However, costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Otezla and how much the copay or coinsurance is. If you have not met your deductible, you may have to pay the full out-of-pocket costs for Otezla. Alternatively, a SingleCare savings card can help you access this prescription drug at a reduced cash price of $4,424.84 for 60, 30mg Tablet.

How to save on Otezla

Amgen, the manufacturer of Otezla, currently offers a savings card through the Otezla Co-Pay Program. Eligible commercially insured patients could have the entire cost of their prescription fills covered. Contact the manufacturer to learn more about the eligibility criteria. 

In addition, the Amgen Safety Net Foundation (ASNF) offers a patient assistance program that could help eligible patients obtain Otezla at a lower cost or for free. Eligible uninsured and underinsured patients could receive financial assistance to purchase Otezla. The Patient Access Network Foundation (PAN) is another organization that may offer a patient assistance program to eligible patients for Otezla. 

There may be other ways to save on Otezla with Otezla manufacturer coupons, rebates, free trials, and special offers. For example, you may be able to save by using SingleCare. The SingleCard discount card is a free savings option that could save you up to 80% on your prescription and over-the-counter medications. 

Is there a generic of Otezla?

Otezla is available as a brand-name drug, as well as a generic version called apremilast.

What is Otezla?

Otezla (apremilast) is a prescription medication approved for treating:

  • Plaque psoriasis in adults who are candidates for phototherapy or systemic therapy

  • Adults with active psoriatic arthritis

  • Oral ulcers associated with Behçet's Disease

Otezla is FDA-approved for use in adults only and is not approved for use in people under the age of 18 years.

Otezla is a PDE4 inhibitor that works inside inflammatory cells to reduce PDE4 activity. Decreased PDE4 activity is believed to help reduce the inflammation that occurs in people with psoriatic disease. Reducing inflammation in the body may help lessen certain symptoms, such as redness, swelling, and pain. 

Otezla is usually taken twice daily. Treatment with Otezla is usually started at a low dose and then increased gradually to reduce the risk of gastrointestinal side effects. Otezla should only be taken as prescribed by a healthcare provider. 

What are the side effects of Otezla?

The most common side effects of Otezla include headache, diarrhea, and nausea. However, side effects often go away on their own as the body adjusts to the medication. Other potential side effects include upper respiratory tract infections, fatigue, vomiting, decreased appetite, weight loss, insomnia, and back pain. 

Serious side effects of {{drug}} include allergic reactions. Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as hives, itching, swelling of the face or throat, or trouble breathing. Other serious side effects may include severe vomiting and severe diarrhea.

Tell your doctor or healthcare provider if you have a history of depression before taking Otezla. The use of Otezla has been reported to cause worsened symptoms of depression, suicidal thoughts, or other changes in mood. You should also tell your healthcare provider about other medical conditions you may have, including kidney disease. 

Before taking Otezla, tell your healthcare provider about all the medications you take. Tell your healthcare provider if you take certain seizure medication, such as carbamazepine, phenobarbital, or phenytoin—or a drug called rifampin used to treat tuberculosis. These medications can decrease the effectiveness of Otezla. 

Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before taking Otezla. 

This is not a complete list of side effects associated with Otezla. Consult a healthcare provider for more information about other possible adverse effects, drug interactions, warnings, and precautions before starting treatment with Otezla.

Does Otezla cause weight loss?

Weight loss has been reported in clinical trials of Otezla. A decrease in weight of 5% to 10% was reported in some patients taking Otezla. Body weight may need to be monitored regularly while taking Otezla. Tell your healthcare provider if you experience unexpected weight loss while taking Otezla. 

How long does Otezla starter pack last?

Otezla is available in two-week and 28-day starter packs. The dosage of Otezla needs to be gradually increased to reduce the risk of gastrointestinal side effects, such as diarrhea, nausea, and vomiting. 

Your healthcare provider may give you a 14-day starter pack. Or, they may prescribe the 28-day starter pack through a specialty pharmacy.

The two-week and 28-day starter parks contain a titration pack plus enough 30 mg tablets for one or three additional weeks of treatment. The initial blister titration pack in each starter pack lasts a total of seven days. It contains the tablets needed to gradually increase the dosage of Otezla to 30 mg twice daily. This schedule helps reduce stomach problems. 

The titration schedule is as follows:

  • Day 1: 10 mg in the morning

  • Day 2: 10 mg in the morning and 10 mg in the evening

  • Day 3: 10 mg in the morning and 20 mg in the evening

  • Day 4: 20 mg in the morning and 20 mg in the evening

  • Day 5: 20 mg in the morning and 30 mg in the evening

  • Day 6 and onward: 30 mg twice daily

Is Otezla the same as Humira?

Otezla and Humira are not the same. Otezla is an oral medication that can treat psoriatic arthritis, plaque psoriasis, and oral ulcers associated with Behçet’s Disease. 

Humira is an injectable medicine. Like Otezla, it can treat psoriatic arthritis and plaque psoriasis but not oral ulcers associated with Behçet’s Disease. Humira also can treat many other conditions, such as rheumatoid arthritis, Crohn’s disease, uveitis, and others.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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