What is Sporanox: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Sporanox overview

BRAND NAMES:

  • Onmel, Sporanox, Tolsura

Generic Names:

  • Itraconazole

Uses:

  • Treats fungal infections.

Therapeutic Classes:

  • Antifungal

Forms:

  • Capsule, Liquid, Tablet

How it’s taken:

  • By mouth

What form(s) does Sporanox come in

  • Capsule

  • Liquid

  • Tablet

What are common Sporanox doses?

  • Bottle 150ML of 10MG/ML

  • Capsule 100MG

Common Sporanox prescriptions

  • Sporanox
    150ml of 10mg/ml bottle

  • Sporanox
    100mg capsule

How to take Sporanox

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Capsule or tablet: Take it with a full meal. Swallow the capsule or tablet whole. Take the tablets at the same time each day.

  • Oral liquid: Take it without food. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Swish the oral liquid in your mouth for several seconds and then swallow it.

  • Use only the brand of medicine your doctor prescribed. Other brands may not work the same way.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses. It may take several weeks or months for your infection to clear up completely.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Use only the brand of medicine your doctor prescribed. Other brands may not work the same way.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Oral liquid: Take it without food. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Swish the oral liquid in your mouth for several seconds and then swallow it.

  • Capsule or tablet: Take it with a full meal. Swallow the capsule or tablet whole. Take the tablets at the same time each day.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses. It may take several weeks or months for your infection to clear up completely.

Sporanox contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to itraconazole or similar medicines, or if you have heart failure. Do not use this medicine to treat a fungal nail infection if you are pregnant.

Sporanox warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, lung problems (including COPD), edema (body swelling), HIV infection or AIDS, or cystic fibrosis. Tell your doctor if you have had an organ transplant.

  • This medicine may cause the following problems:New or worsening heart failureLiver problemsHeart rhythm problems, which can be life-threatening (when used with certain medicines)Nerve problemsTemporary or permanent hearing loss

  • This medicine may make you feel dizzy or have blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Numbness, tingling, or burning pain anywhere in your body

  • Rapid weight gain, swelling in your face, hands, ankles, or feet

Sporanox interactions

  • Do not use itraconazole together with avanafil, cisapride, disopyramide, dofetilide, dronedarone, eliglustat, eplerenone, felodipine, irinotecan, isavuconazole, ivabradine, lomitapide, lurasidone, methadone, naloxegol, nisoldipine, oral midazolam, pimozide, quinidine, ranolazine, ticagrelor, triazolam, an ergot medicine (including dihydroergotamine, ergonovine, ergotamine, methylergonovine) or medicines to lower cholesterol (including lovastatin, simvastatin). Tell your doctor if you also take colchicine, fesoterodine, solifenacin, or telithromycin, especially if you have kidney or liver disease.

  • Tell your doctor if you also take alfuzosin, aliskiren, apixaban, bedaquiline, conivaptan, darifenacin, everolimus, fentanyl, isoniazid, lumacaftor/ivacaftor, rifabutin, rifampin, riociguat, rivaroxaban, Saccharomyces boulardii, salmeterol, sildenafil, silodosin, sirolimus, tadalafil, tamsulosin, temsirolimus, tolvaptan, vardenafil, vorapaxar, medicine to treat cancer (including dasatinib, ibrutinib, nilotinib, regorafenib), medicine to treat HIV infection (including efavirenz, elbasvir/grazoprevir, nevirapine, simeprevir), or medicine to treat seizures (including carbamazepine, phenobarbital, phenytoin). It is best to avoid these drugs for 2 weeks before, during, and after treatment with itraconazole.

  • Many other drugs can interact with itraconazole. Make sure your doctor knows about all other medicines you are using.

  • If you are taking stomach medicine (including an antacid, H2 blocker, or proton pump inhibitor), take it at least 2 hours before or 2 hours after using this medicine.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Sporanox side effects

Serious Side Effects

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Numbness, tingling, or burning pain anywhere in your body

  • Chest pain, trouble breathing, coughing up blood, cold sweat, bluish-colored skin

  • Hearing loss

  • Fast, pounding, or uneven heartbeat

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Rapid weight gain, swelling in your face, hands, ankles, or feet

Less Serious Side Effects

  • Diarrhea

  • Blurred or double vision, dizziness

  • Headache