What is Memantine Hcl: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Memantine Hcl overview

BRAND NAMES:

  • Namenda XR Titration Pack, Namenda, Namenda Titration Pack, Namenda XR

Generic Names:

  • Memantine Hcl

Uses:

  • Treats dementia associated with Alzheimer disease.

Therapeutic Classes:

  • Central Nervous System Agent

Forms:

  • Long Acting Capsule, Liquid, Tablet

How it’s taken:

  • By mouth

What is Memantine Hcl used for?

Namenda is a medication used to treat Alzheimer’s disease related dementia (confusion). This drug blocks glutamate (a brain chemical) that may play a role in Alzheimer’s disease symptoms. Namenda is a brand version of the drug memantine HCL. In 2000 the drug was developed for use in Alzheimer’s disease. In the treatment of Alzheimer’s disease related dementia, Namenda use is common.

What form(s) does Memantine Hcl come in

  • Long Acting Capsule

  • Liquid

  • Tablet

What are common Memantine Hcl doses?

  • Tablet 5MG

  • Tablet 10MG

  • Disp Pack 49 Tablets

  • Bottle 10GM of

  • Bottle 240ML of 2MG/ML

  • Bottle 360ML of 2MG/ML

Common Memantine Hcl prescriptions

  • Memantine HCl
    240ml of 2mg/ml bottle

  • Memantine HCl
    360ml of 2mg/ml bottle

  • Memantine HCl
    5ml of 10mg/5ml cup

  • Memantine HCl
    49 tablets disp pack

  • Memantine HCl
    10mg tablet

  • Memantine HCl
    5mg tablet

How to take Memantine Hcl

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Most people need to wait at least one week between dose changes.

  • Oral routeYou may take this medicine with or without food.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.

  • Oral routeIf you cannot swallow the extended-release capsule, you may open it and pour the medicine into a small amount of soft food such as pudding, yogurt, or applesauce. Stir this mixture well and swallow it without chewing.

  • For the liquid and extended-release capsule form: Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • For the liquid and extended-release capsule form: Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Oral routeYou may take this medicine with or without food.

  • Oral routeIf you cannot swallow the extended-release capsule, you may open it and pour the medicine into a small amount of soft food such as pudding, yogurt, or applesauce. Stir this mixture well and swallow it without chewing.

  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Most people need to wait at least one week between dose changes.

What to do if you miss a dose of Memantine Hcl

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Memantine Hcl contraindications

  • You should not use this medicine if you have had an allergic reaction to memantine.

Memantine Hcl warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bladder problems or difficulty with urination, or epilepsy or seizures.

  • Check with your doctor right away if you get a urinary tract infection. This includes any infection in your bladder or kidneys. Your dose of this medicine might need to be changed while you have an infection.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Lightheadedness, dizziness, or fainting.

  • Seeing or hearing things that are not there.

  • Severe sleepiness, restlessness, or confusion.

  • Sudden or severe headache.

Memantine Hcl interactions

  • Make sure your doctor knows if you are also using amantadine (Symmetrel®), cimetidine (Tagamet®), ketamine (Ketalar®), metformin (Glucophage®), quinidine (Cardioquin®, Quinaglute®, Quinidex®), or ranitidine (Zantac®).

  • Tell your doctor if you are also using a diuretic or "water pill" (such as acetazolamide, hydrochlorothiazide [HCTZ], methazolamide, triamterene, Diamox®, Dyazide®, Dyrenium®, Maxzide®, or Neptazane®) or an antacid or laxative that contains sodium bicarbonate, baking soda, or bicarbonate of soda (such as Alka-Seltzer®).

  • Tell your doctor if you smoke or if you are using a stop-smoking aid that contains nicotine (such as Nicoderm®, Nicorette®, or Nicotrol®) or a cold or cough medicine that contains dextromethorphan (DayQuil®, NyQuil®, Robitussin® DM, or TheraFlu®).

Memantine Hcl side effects

Serious Side Effects

  • Sudden or severe headache.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate.

  • Chest pain.

  • Lightheadedness, dizziness, or fainting.

  • Seeing or hearing things that are not there.

  • Severe sleepiness, restlessness, or confusion.

Less Serious Side Effects

  • Feeling aggressive or depressed.

  • Weight gain.

  • Constipation, diarrhea, vomiting, or stomach pain.

  • Tiredness or weakness.

  • Back pain.

  • Mild headache.