What is Donepezil Hcl: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Donepezil Hcl overview

BRAND NAMES:

  • Aricept

Generic Names:

  • Donepezil Hcl

Uses:

  • Treats Alzheimer disease.

Therapeutic Classes:

  • Central Nervous System Agent

Forms:

  • Dissolving Tablet, Tablet

How it’s taken:

  • By mouth

What form(s) does Donepezil Hcl come in

  • Dissolving Tablet

  • Tablet

What are common Donepezil Hcl doses?

  • Tablet 5MG

  • Tablet 10MG

  • Tablet 23MG

  • Tablet Disintegrating 5MG

  • Tablet Disintegrating 10MG

Common Donepezil Hcl prescriptions

  • Donepezil HCl
    10mg tablet

  • Donepezil HCl
    23mg tablet

  • Donepezil HCl
    5mg tablet

  • Donepezil HCl
    10mg tablet disintegrating

  • Donepezil HCl
    5mg tablet disintegrating

How to take Donepezil Hcl

  • Missed dose: Skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Disintegrating tablet: Make sure your hands are dry before you handle the disintegrating tablet. Peel back the foil from the blister pack, then remove the tablet. Do not push the tablet through the foil. Place the tablet in your mouth. After it has melted, swallow or take a drink of water.

  • Tablet: Swallow the 23-mg tablet whole. Do not crush, break, or chew it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Disintegrating tablet: Make sure your hands are dry before you handle the disintegrating tablet. Peel back the foil from the blister pack, then remove the tablet. Do not push the tablet through the foil. Place the tablet in your mouth. After it has melted, swallow or take a drink of water.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Tablet: Swallow the 23-mg tablet whole. Do not crush, break, or chew it.

  • Missed dose: Skip the missed dose and take your next dose at the regular time. Do not take extra medicine to make up for a missed dose.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

Donepezil Hcl contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to donepezil or to medicines that contain piperidine.

Donepezil Hcl warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Seizures

  • Severe stomach pain

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • This medicine may cause the following problems: Slow heartbeatStomach or bowel bleedingSeizures

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, lung disease, asthma or other breathing problems, stomach ulcers or bleeding, or trouble urinating.

  • Vomiting of blood or material that looks like coffee grounds

  • Unusual bleeding, bruising, or weakness

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Donepezil Hcl interactions

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • This medicine may cause the following problems: Slow heartbeatStomach or bowel bleedingSeizures

  • Some medicines can affect how donepezil works. Tell your doctor if you are using any of the following: Bethanechol, carbamazepine, dexamethasone, ketoconazole, phenobarbital, phenytoin, quinidine, or rifampinNSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen)

Donepezil Hcl side effects

Serious Side Effects

  • Change in how much or how often you urinate

  • Vomiting of blood or material that looks like coffee grounds

  • Seizures

  • Unusual bleeding, bruising, or weakness

  • Lightheadedness, dizziness, fainting

  • Bloody or black, tarry stools

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, slow or uneven heartbeat, trouble breathing

  • Severe stomach pain

Less Serious Side Effects

  • Mild nausea, vomiting, or diarrhea

  • Weight loss