What is Arixtra: Uses, Warnings & Interactions

Updated Jan. 12, 2021  •  Published Dec. 30, 2020

Arixtra overview

BRAND NAMES:

  • Fondaparinux Sodium Novaplus, Arixtra

Generic Names:

  • Fondaparinux Sodium

Uses:

  • Treats blood clots and prevents them from forming after hip, knee, or stomach surgery. This medicine is a blood thinner.

Therapeutic Classes:

  • Anticoagulant

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Arixtra used for?

Arixtra is a prescription medication used to treat patients with deep vein thrombosis (DVT). A condition that causes blood to clot in the legs or lungs. This medication is used together with another anticoagulant to stop the blood clotting substance in the in the blood. This reduces the risk of heart attack, stroke, or breathing problems.

What form(s) does Arixtra come in

  • Injectable

What are common Arixtra doses?

  • Syringe 0.5ML of 2.5MG/0.5ML

  • Syringe 10ML of 5MG/0.4ML

  • Syringe 0.60000002384185791ML of 7.5MG/0.6ML

  • Syringe 0.800000011920929ML of 10MG/0.8ML

Common Arixtra prescriptions

  • Arixtra
    0.4ml of 5mg/0.4ml syringe

  • Arixtra
    0.5ml of 2.5mg/0.5ml syringe

  • Arixtra
    0.6ml of 7.5mg/0.6ml syringe

  • Arixtra
    0.8ml of 10mg/0.8ml syringe

  • Arixtra
    10ml of 5mg/0.4ml syringe

How to take Arixtra

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Alternate sides of your abdomen for each injection.

  • After you remove the needle guard, do not let the needle touch anything before you inject the medicine. This will help prevent infection.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Injection routeIf you store this medicine at home, keep it at room temperature, away from heat and direct light.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Alternate sides of your abdomen for each injection.

  • Injection routeA nurse or other health provider will give you this medicine.

  • After you remove the needle guard, do not let the needle touch anything before you inject the medicine. This will help prevent infection.

  • Injection routeIf you store this medicine at home, keep it at room temperature, away from heat and direct light.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Arixtra contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to fondaparinux.

Arixtra warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, any bleeding problems, high blood pressure, diabetic retinopathy, a stomach ulcer, or a history of stroke or heart infection. Tell your doctor if you recently had brain, back, or eye surgery. Tell your doctor if you have an allergy to latex.

  • This medicine may cause the following problems:Increased risk of bleeding Risk of spinal or epidural blood clots after spinal procedures

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tiny red dots on the skin, especially on the lower legs

  • Unexplained nosebleeds

  • Unusual bleeding, bruising, or weakness

Arixtra interactions

  • This medicine may cause the following problems:Increased risk of bleeding Risk of spinal or epidural blood clots after spinal procedures

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Some medicines can affect how fondaparinux works. Tell your doctor if you are using an NSAID pain or arthritis medicine (such as aspirin, ibuprofen, naproxen) or other blood thinners (such as clopidogrel, warfarin).

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Arixtra side effects

Serious Side Effects

  • Tiny red dots on the skin, especially on the lower legs

  • Change in how much or how often you urinate

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Loss of bowel or bladder control

  • Unexplained nosebleeds

  • Numbness or tingling in your legs, back pain

  • Unusual bleeding, bruising, or weakness

  • Blood in your urine or stools

Less Serious Side Effects

  • Mild bleeding, itching, or rash where the shot was given