What is Uloric: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Uloric overview

BRAND NAMES:

  • Uloric

Generic Names:

  • Febuxostat

Uses:

  • Lowers uric acid levels in the blood in patients with gout.

Therapeutic Classes:

  • Antigout

Forms:

  • Tablet

How it’s taken:

  • By mouth

What form(s) does Uloric come in

  • Tablet

What are common Uloric doses?

  • Tablet 40MG

  • Tablet 80MG

Common Uloric prescriptions

  • Uloric
    40mg tablet

  • Uloric
    80mg tablet

How to take Uloric

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Your gout may get worse when you start using this medicine. Keep using this medicine even if this happens. Your doctor may give you other medicines (including colchicine or NSAID pain medicines) to help prevent these gout attacks.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Your gout may get worse when you start using this medicine. Keep using this medicine even if this happens. Your doctor may give you other medicines (including colchicine or NSAID pain medicines) to help prevent these gout attacks.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Uloric

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Uloric contraindications

  • This medicine is not right for everyone. Do not use this medicine if you had an allergic reaction to febuxostat.

Uloric warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, brain or blood vessel disease, diabetes, Lesch-Nyhan syndrome (rare, inherited enzyme problem), cancer, or a history of heart disease or stroke. Tell your doctor if you had an organ transplant.

  • This medicine may cause the following problems:Increased risk for chest pain, heart attack, stroke, or deathLiver problemsSerious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS)

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Dark-colored urine or pale stools.

  • Dry mouth, increased thirst, or muscle cramps.

  • Fast, slow, or uneven heartbeat.

  • Fever, chills, cough, sore throat, and body aches.

  • Joint or muscle pain.

  • Lightheadedness or fainting.

  • Numbness or weakness in your arm or leg, or on one side of your body.

  • Pain in your lower leg (calf).

  • Sudden and severe stomach pain, nausea, or vomiting.

  • Sudden or severe headache, problems with vision, speech, or walking.

  • Swelling in your hands, ankles, or feet.

  • Unusual bleeding, bruising, or weakness.

  • Yellowing of your skin or the whites of your eyes.

Uloric interactions

  • Do not use this medicine together with azathioprine or mercaptopurine.

  • Some medicines can affect how febuxostat works. Tell your doctor if you are using theophylline.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Uloric side effects

Serious Side Effects

  • Sudden or severe headache, problems with vision, speech, or walking.

  • Yellowing of your skin or the whites of your eyes.

  • Unusual bleeding, bruising, or weakness.

  • Unusual bleeding, bruising, or weakness

  • Sudden or severe headache, problems with vision, speech, or walking

  • Swollen, painful, or tender lymph glands in the neck, armpit, or groin

  • Swelling in your hands, ankles, or feet.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Change in how much or how often you urinate, cloudy urine

  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, unusual sweating, faintness, coughing up blood

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Fever, chills, cough, sore throat, body aches

  • Joint or muscle pain

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Pain in your lower leg (calf)

  • Swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Hair loss.

  • Blurred vision.

  • Warmth or redness in your face, neck, arms, or upper chest.

  • Anxiety, depression, or trouble sleeping.

  • Dizziness or drowsiness.

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet.

  • Weight changes.

  • Constipation, heartburn, indigestion, loss of appetite, mild nausea, or stomach pain.

  • Mild skin rash.