Trintellix Coupons & Prices

Trintellix (vortioxetine) is an antidepressant that works by balancing serotonin levels in the brain. Serotonin is an important neurotransmitter that plays a role in mood, sleep, and appetite. Trintellix is approved to treat major depressive disorder and is only available as a brand-name drug. There is no generic version of Trintellix currently on the market. The average retail price of Trintellix is $663.65 for 30, 20MG Tablet. If you are underinsured or uninsured, Trintellix may be an expensive prescription medication. You could pay $440.21 for 30, 20mg Tablet for your next prescription or refill by using a SingleCare Trintellix coupon.

5 Tablet5mgEdit

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Trintellix coupon at Walgreens Pharmacy
$443.21
$ 440.21
  • How is this calculated?

  • Price if you don’t sign up:

    $443.21

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $440.21

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Trintellix coupon at Walmart Neighborhood Market Pharmacy
$449.20
$ 446.20
  • How is this calculated?

  • Price if you don’t sign up:

    $449.20

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $446.20

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Trintellix coupon at Walmart Pharmacy
$449.20
$ 446.20
  • How is this calculated?

  • Price if you don’t sign up:

    $449.20

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $446.20

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Trintellix coupon at Cvs Pharmacy
$455.74
$ 452.74
  • How is this calculated?

  • Price if you don’t sign up:

    $455.74

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $452.74

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Trintellix coupon at Kroger Pharmacy
$473.32
$ 470.32
  • How is this calculated?

  • Price if you don’t sign up:

    $473.32

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $470.32

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Trintellix coupon at Harris Teeter Pharmacy
$473.32
$ 470.32
  • How is this calculated?

  • Price if you don’t sign up:

    $473.32

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $470.32

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$485.82
$ 482.82
  • How is this calculated?

  • Price if you don’t sign up:

    $485.82

  • One-time sign-up bonus

    -$3.00

  • Price with free sign-up

    $482.82

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 507.46
$ 547.94

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

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About

Trintellix (vortioxetine) is an antidepressant that works by balancing serotonin levels in the brain. Serotonin is an important neurotransmitter that plays a role in mood, sleep, and appetite. Trintellix is approved to treat major depressive disorder and is only available as a brand-name drug. There is no generic version of Trintellix currently on the market. The average retail price of Trintellix is $663.65 for 30, 20MG Tablet. If you are underinsured or uninsured, Trintellix may be an expensive prescription medication. You could pay $440.21 for 30, 20mg Tablet for your next prescription or refill by using a SingleCare Trintellix coupon.

Trintellix Price History & Information

Price History for Trintellix

30 count, 20mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Trintellix

30 count, 20mg
PharmacyTrintellix Retail PriceTrintellix SingleCare Price
CVS Pharmacy$562.65$447.11
Walmart$570.93$470.24
Walgreens$565.14$490.41
Kroger Pharmacy$566.84$455.68
Albertsons Pharmacy$556.13$458.68
Rite Aid Pharmacy$607.67$475.47

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

Trintellix FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Trintellix cost without insurance?

Without insurance, Trintellix costs an average price of $663.65 for 30, 20MG Tablet. The cost of Trintellix will depend on different factors, such as the pharmacy you use and the quantity prescribed. You may have to check with different pharmacies to find the best price. If you don’t have insurance, you can get a free SingleCare card that could lower the price to $440.21 for 30, 20mg Tablet for Trintellix. 

How much does Trintellix cost with insurance?

The cost of Trintellix with insurance depends on the plan you’re enrolled in. You can check with your pharmacist or insurance company to determine your copay with insurance. Trintellix is a brand-name drug that is usually placed on higher tiers of drug formularies. In other words, you may have to pay more for Trintellix than other low-cost alternatives with insurance. Instead, you may be able to get a better deal by paying cash with a SingleCare card. The lowest price on SingleCare is $440.21 for 30, 20mg Tablet of Trintellix. You can ask the pharmacist to run your SingleCare card to compare prices before you pay for your Trintellix prescription.

Does Medicare cover Trintellix and how much does it cost?

Trintellix is covered by some insurance plans and Medicare. Check with your prescription drug plan to determine your copay or coinsurance amount for Trintellix. The cost of Trintellix with Medicare can vary depending on the plan. If you don’t have enough coverage with Medicare, you may be able to save more by using a SingleCard coupon. Use SingleCare's search tool to find the pharmacy with the best price.

How to save on Trintellix

A way to save on Trintellix is to use a SingleCare card. You may find that you save the most money by using a SingleCare Trintellix savings card. 

Is there a generic of Trintellix?

Trintellix is a brand-name drug. Trintellix was formerly known as Brintellix. However, the FDA approved its name change to avoid confusion with Brilinta, which is a blood thinner. The generic version of Trintellix is vortioxetine and is not yet available. 

What is Trintellix?

Trintellix is an antidepressant approved to treat major depressive disorder (MDD). It works by balancing serotonin levels in the brain, which may help improve mood, appetite, sleep health, and energy levels in people with depression. Vortioxetine is the active ingredient in Trintellix. Because it works differently from other antidepressants, vortioxetine is considered a miscellaneous or atypical antidepressant. It may also be classified as a selective serotonin reuptake inhibitor (SSRI) and serotonin modulator. Trintellix is usually reserved to treat depression that isn’t improved with other antidepressants.

What strengths of Trintellix are available?

Trintellix is available as an oral tablet in strengths of 5 mg, 10 mg, and 20 mg. Trintellix is taken by mouth, usually once daily with or without food. Your healthcare provider may start you at a low dose and gradually increase the dose, depending on your response to treatment. If you experience side effects from Trintellix, your healthcare provider may adjust your dosage. Suddenly stopping this antidepressant could cause rebound depression or withdrawal symptoms.

Always follow your healthcare provider's medical advice and read the medication guide for more information about taking Trintellix.

What are the side effects of Trintellix?

Common side effects of Trintellix include nausea, vomiting, and constipation. Other side effects may include dizziness, gas, dry mouth, abnormal dreams, loss of libido, and sexual dysfunction. Tell a healthcare provider if these side effects persist or worsen. 

A possible serious side effect of Trintellix is serotonin syndrome. Symptoms of serotonin syndrome include fast heart rate, blood pressure changes, dizziness, agitation, confusion, and coma. Seek medical attention right away if you experience these side effects. Other serious side effects include an increased risk of bleeding, manic episodes, eye problems, and low blood sodium levels (hyponatremia)

To avoid a drug interaction and decrease the likelihood of serious side effects, tell your healthcare provider about all the medications you take. Taking certain drugs with Trintellix may increase the risk of adverse effects. 

Antidepressants, such as Trintellix, may increase the risk of suicidal thoughts and behavior in some people. Notify your healthcare provider if you suspect your condition is worsening rather than improving while taking Trintellix. 

This is not a complete list of side effects.

How long does Trintellix take to work?

Clinical studies have shown that it can take around two weeks for Trintellix to start improving symptoms of depression. However, the maximum effects of Trintellix may not be seen until four weeks after starting treatment. In some cases, it can take up to eight weeks or longer to experience the full benefits of Trintellix. 

Is Trintellix good for anxiety?

Trintellix is not FDA approved to treat anxiety. Still, some healthcare providers may prescribe Trintellix off-label for anxiety disorders. Clinical studies have shown that Trintellix may improve symptoms of anxiety.

What kind of antidepressant is Trintellix?

Trintellix (or vortioxetine) is a unique antidepressant in that it is a selective serotonin reuptake inhibitor (SSRI) and a serotonin receptor modulator. It works by increasing serotonin levels and activating certain serotonin receptors in the brain. Serotonin is a neurotransmitter that contributes to mental well-being and mood, among other functions.

What antidepressant is similar to Trintellix?

Trintellix is a unique drug in that there is no other drug that works exactly like Trintellix. However, other antidepressants have similar effects on serotonin. Selective serotonin reuptake inhibitors (SSRIs) help increase serotonin levels and include drugs like Prozac (fluoxetine), Zoloft (sertraline), and Lexapro (escitalopram). 

Other atypical antidepressants that may be prescribed instead of Trintellix include Wellbutrin (bupropion), Viibryd (vilazodone), and Remeron (mirtazapine). Consult with a healthcare provider to determine the most appropriate treatment option for you. 

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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