What is Tenofovir Disoproxil Fumarate: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Tenofovir Disoproxil Fumarate overview

BRAND NAMES:

  • Viread

Generic Names:

  • Tenofovir Disoproxil Fumarate

Uses:

  • Treats HIV infection and hepatitis B virus (HBV) infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Powder, Tablet

How it’s taken:

  • By mouth

What form(s) does Tenofovir Disoproxil Fumarate come in

  • Powder

  • Tablet

What are common Tenofovir Disoproxil Fumarate doses?

  • Tablet 300MG

  • Bottle 30 Tablets

Common Tenofovir Disoproxil Fumarate prescriptions

  • Tenofovir Disoproxil Fumarate
    30 tablets bottle

  • Tenofovir Disoproxil Fumarate
    300mg tablet

How to take Tenofovir Disoproxil Fumarate

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Tenofovir is used with other medicines to treat HIV infection. Take all other medicines that your doctor has prescribed as part of your combination treatment.

  • Do not stop using this medicine without first checking with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Oral powder: Measure the oral powder with the dosing scoop that comes with the package. Mix the oral powder with 2 to 4 ounces of soft food (including applesauce, baby food, yogurt). Swallow this mixture right away. It is less likely to have a bitter taste if you take it as soon as it is mixed. Do not mix the oral powder with a liquid. The powder will not mix correctly and will float on top. Do not store the scoop inside the package with the powder.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not use this medicine if the seal on the bottle is broken or missing. Keep the bottle tightly closed. Keep the medicine in its original bottle.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral powder: Measure the oral powder with the dosing scoop that comes with the package. Mix the oral powder with 2 to 4 ounces of soft food (including applesauce, baby food, yogurt). Swallow this mixture right away. It is less likely to have a bitter taste if you take it as soon as it is mixed. Do not mix the oral powder with a liquid. The powder will not mix correctly and will float on top. Do not store the scoop inside the package with the powder.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not use this medicine if the seal on the bottle is broken or missing. Keep the bottle tightly closed. Keep the medicine in its original bottle.

  • Do not stop using this medicine without first checking with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Tenofovir is used with other medicines to treat HIV infection. Take all other medicines that your doctor has prescribed as part of your combination treatment.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Tenofovir Disoproxil Fumarate contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to tenofovir.

Tenofovir Disoproxil Fumarate warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, or bone problems (including osteoporosis).

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Worsening of hepatitis B infection, when treatment is stoppedNew or worsening kidney problemsLower bone mineral densityLactic acidosis (too much acid in the blood)Liver problems

  • Your immune system may get stronger when you start using this medicine. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tenofovir Disoproxil Fumarate interactions

  • Some medicines can affect how tenofovir works. Tell your doctor if you are using any of the following:Acyclovir, adefovir, atazanavir, bictegravir/emtricitabine/tenofovir alafenamide, cidofovir, darunavir, didanosine, ganciclovir, ledipasvir/sofosbuvir, lopinavir/ritonavir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voxilaprevir, valacyclovir, valganciclovirAminoglycoside antibiotic (including gentamicin)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Lactic acidosisSevere liver problemsWorsening of hepatitis B infection, when treatment is stoppedKidney problemsLower bone mineral density

  • Your immune system may get stronger when you start taking this medicine. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tenofovir Disoproxil Fumarate side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bone, muscle, or joint pain

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Decrease in how much or how often you urinate

  • Fast or troubled breathing, lightheadedness, severe weakness, confusion

Less Serious Side Effects

  • Diarrhea

  • Rash

  • Anxiety, depression

  • Headache