Systane Coupons & Prices

Systane is a family of over-the-counter artificial tears eye drops, ointments, and gel remedies for dry eye relief or irritated eyes. These eye care products add moisture to the surface of the eye and other ingredients to slow evaporation from the surface of the eye. In addition, Systane Z

0.5 Bottle10ml of 0.4-0.3%Edit

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Systane coupon at Walgreens Pharmacy
$ 2.55
Systane coupon at Rite Aid Pharmacy
$7.63
$ 4.63
  • How is this calculated?

  • Price if you don’t sign up:

    $7.63

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $4.63

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Systane coupon at Kroger Pharmacy
$12.09
$ 9.09
  • How is this calculated?

  • Price if you don’t sign up:

    $12.09

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $9.09

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Systane coupon at Harris Teeter Pharmacy
$12.09
$ 9.09
  • How is this calculated?

  • Price if you don’t sign up:

    $12.09

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $9.09

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Systane coupon at Food Lion Pharmacy
$ 13.91
Systane coupon at Walmart Neighborhood Market Pharmacy
$18.74
$ 15.74
  • How is this calculated?

  • Price if you don’t sign up:

    $18.74

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $15.74

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$18.74
$ 15.74
  • How is this calculated?

  • Price if you don’t sign up:

    $18.74

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $15.74

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 15.91

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

Save big on your prescriptions
with the free SingleCare app.
4.8 average rating
About Lubricating Eye Drops

Systane is a family of over-the-counter artificial tears eye drops, ointments, and gel remedies for dry eye relief or irritated eyes. These eye care products add moisture to the surface of the eye and other ingredients to slow evaporation from the surface of the eye. In addition, Systane Zaditor is an antihistamine eye drop that relieves eye irritation and inflammation due to allergies. Systane also offers a family of vitamin supplements that promote general eye and vision health. On average, Systane costs $15.80 for 1, 15ML of 0.4-0.3% Bottle but you will pay with a free SingleCare Systane coupon. SingleCare discounts are eligible for over-the-counter products like Systane, when prescribed by a physician. And SingleCare is accepted at pharmacies near you for $2.55 for 1, 15ml of 0.4-0.3% Bottle.

Systane Price History & Information

Price History for Systane

1 count, 15ml of 0.4-0.3%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Systane

1 count, 15ml of 0.4-0.3%
PharmacySystane Retail PriceSystane SingleCare Price
CVS Pharmacy$12.09$4.99
Walmart$6.90$6.90
Walgreens$11.43$2.63
Kroger Pharmacy$7.32$7.02
Albertsons Pharmacy$14.70$12.00
Rite Aid Pharmacy$13.17$8.10

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Systane

Systane is a family of over-the-counter artificial tears eye drops, ointments, and gel remedies for dry eye relief or irritated eyes. These eye care products add moisture to the surface of the eye and other ingredients to slow evaporation from the surface of the eye. In addition, Systane Zaditor is an antihistamine eye drop that relieves eye irritation and inflammation due to allergies. Systane also offers a family of vitamin supplements that promote general eye and vision health. On average, Systane costs $15.80 for 1, 15ML of 0.4-0.3% Bottle but you will pay with a free SingleCare Systane coupon. SingleCare discounts are eligible for over-the-counter products like Systane, when prescribed by a physician. And SingleCare is accepted at pharmacies near you for $2.55 for 1, 15ml of 0.4-0.3% Bottle.

Systane FAQs

Medically reviewed by Kristi C. TorresPharm.D.
Licensed Pharmacist

How much does Systane cost without insurance?

The retail price of Systane averages $15.80 for 1, 15ML of 0.4-0.3% Bottle. Systane costs with a Systane coupon from SingleCare with a prescription. In fact, you can save up to 80% the retail price on many prescription drugs with a free coupon from SingleCare. 

How much does Systane cost with insurance?

Systane is usually not covered by your insurance, so you will always pay full price rather than a lower, copay price. If your doctor has prescribed Systane, with a printable coupon from SingleCare, Systane costs $2.55 for 1, 15ml of 0.4-0.3% Bottle.

Does Medicare cover Systane and how much does it cost?

Medicare Part D and Medicare Advantage do not cover Systane. Consider instead using a SingleCare Systane coupon if you have a prescription for Systane. With SingleCare, the cost of Systane drops to $2.55 for 1, 15ml of 0.4-0.3% Bottle.

Is there a generic of Systane?

Systane is an over-the-counter brand-name family of topical eye remedies from Alcon. The active ingredients in many of the products are found in over-the-counter artificial tears, including generics.

What is Systane?

Systane is a family of over-the-counter artificial tears eye drops, ointments, and gel remedies for dry or irritated eyes. These eye health products add moisture to the surface of the eye and other ingredients to slow evaporation from the surface of the eye. In addition, Systane Zaditor is an antihistamine eye drop that relieves eye irritation and inflammation due to allergies.

Systane also offers eye vitamin supplements, lubricant eye gels, and nighttime lubricant eye ointments, which all promote general eye, vision, and personal care. 

While Systane provides relief for temporary dry eye symptoms, it may not be appropriate for chronic dry eye. In that case, you may require a prescription eye drop that treats the underlying condition or illness. Consult with your physician or ophthalmologist if you suffer continually from dry eye symptoms.

What are the side effects of Systane?

Common side effects of Systane eye remedies are usually minor and temporary site reactions on the surface of the eye. They include but are not limited to blurred vision, sensitivity to light, redness, and watering of the eye for a short period after the eye drops are applied. Allergic reactions are very rare but are marked by prolonged irritation or redness of the eye, rash, itching, and trouble breathing, among others. Always discontinue Systane if you experience allergic reactions.

Consult your doctor or health care professional for additional information and medical advice.

Medically reviewed by Kristi C. TorresPharm.D.
Licensed Pharmacist

Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.

Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.

Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.

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