Sign up
Log in
EspañolSulfasalazine overview
BRAND NAMES:
Sulfazine, Azulfidine, Azulfidine Entabs, Sulfazine
Generic Names:
Sulfasalazine
Uses:
Treats ulcerative colitis and rheumatoid arthritis.
Therapeutic Classes:
Antirheumatic, Gastrointestinal Agent
Forms:
Tablet, Coated Tablet
How it’s taken:
By mouth
What is Sulfasalazine used for?
Azulfidine is a prescription medication used to treat patients with a bowel disease known as ulcerative colitis. This medication reduces irritation and swelling of the large intestines. This helps to relieve the symptoms such as rectal bleeding, fever, stomach pain, and diarrhea. Azulfidine can also treat patients diagnosed with rheumatoid arthritis.
What form(s) does Sulfasalazine come in
Tablet
Coated Tablet
What are common Sulfasalazine doses?
Tablet 500MG
Tablet Delayed Release 500MG
Bottle 25GM of
Bottle 100GM of
Common Sulfasalazine prescriptions
sulfaSALAzine
500mg tabletsulfaSALAzine
500mg tablet delayed release
How to take Sulfasalazine
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
It is best to take this medicine after meals, at evenly spaced times throughout the day and night. Try not to let more than 8 hours go by between doses, even at night.
Coated tablet: Swallow the tablet whole. Do not crush, break, or chew it.
Drink extra fluids so you will urinate more often and help prevent kidney problems.
Keep using this medicine for the full treatment time, even if you feel better after the first few doses.
If you are using this medicine for rheumatoid arthritis, it may take 4 to 12 weeks before you start feeling better.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
If you are using this medicine for rheumatoid arthritis, it may take 4 to 12 weeks before you start feeling better.
Coated tablet: Swallow the tablet whole. Do not crush, break, or chew it.
Keep using this medicine for the full treatment time, even if you feel better after the first few doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
It is best to take this medicine after meals, at evenly spaced times throughout the day and night. Try not to let more than 8 hours go by between doses, even at night.
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Drink extra fluids so you will urinate more often and help prevent kidney problems.
Sulfasalazine contraindications
This medicine is not right for everyone. Do not use it if you had an allergic reaction to sulfasalazine, sulfa drugs, or any salicylate medicine, or if you have bowel or bladder blockage, or porphyria.
Sulfasalazine warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, trouble urinating, asthma, blood or bone marrow problems, or an enzyme problem called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
This medicine may decrease the amount of sperm a man makes and affect his ability to have children while using this medicine. If you are a man who plans to have children, talk with your doctor first.
This medicine may cause the following problems.Liver damageSevere anemia or other blood disordersInfectionsSevere allergic reactions, especially skin reactions
Your skin or urine may turn orange or yellow while you are using this medicine. This is normal and nothing to worry about.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Unusual bleeding, bruising, or weakness
Sulfasalazine interactions
Some medicines can affect how sulfasalazine works. Tell your doctor if you are using digoxin or a folic acid supplement.
This medicine may decrease the amount of sperm a man makes and affect his ability to have children while using this medicine. If you are a man who plans to have children, talk with your doctor first.
This medicine may cause the following problems.Liver damageSevere anemia or other blood disordersInfectionsSevere allergic reactions, especially skin reactions
Your skin or urine may turn orange or yellow while you are using this medicine. This is normal and nothing to worry about.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Sulfasalazine side effects
Serious Side Effects
Swollen, painful, or tender lymph glands in your neck, armpit, or groin
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Severe rash or sores, especially with fever
Fever, chills, cough, sore throat, pale skin, and body aches
Unusual bleeding, bruising, or weakness
Less Serious Side Effects
Headache or dizziness
Mild diarrhea, nausea, vomiting, loss of appetite, or stomach pain (for more than a few days)