What is Seroquel: Uses, Warnings & Interactions

Updated May 16, 2024  •  Published Dec 30, 2020

Seroquel overview

BRAND NAMES:

  • SEROquel, SEROquel XR, Seroquel XR 14-Day Sample Kit

Generic Names:

  • Quetiapine Fumarate

Uses:

  • Treats schizophrenia, bipolar disorder, or depression.

Therapeutic Classes:

  • Antipsychotic

Forms:

  • Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What form(s) does Seroquel come in

  • Tablet

  • Long Acting Tablet

Common Seroquel prescriptions

  • SEROquel
    100 tablets bottle

  • SEROquel
    30 tablets bottle

  • SEROquel
    100mg tablet

  • SEROquel
    200mg tablet

  • SEROquel
    25mg tablet

  • SEROquel
    300mg tablet

  • SEROquel
    400mg tablet

  • SEROquel
    50mg tablet

How to take Seroquel

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. You need to start with a low dose, even if you have used this medicine before.

  • Your doctor may tell you to take the medicine at bedtime, because quetiapine can make you sleepy.

  • Extended-release tablets: Take this medicine either without food or with a light snack (about 300 calories).

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. You need to start with a low dose, even if you have used this medicine before.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Your doctor may tell you to take the medicine at bedtime, because quetiapine can make you sleepy.

  • Extended-release tablets: Take this medicine either without food or with a light snack (about 300 calories).

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Seroquel contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to quetiapine.

Seroquel warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need to have your eyes tested on a regular basis.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • This medicine may make it more difficult for your body to cool down. Be careful not to become overheated during exercise or hot weather, because you could have a heat stroke.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • This medicine may make you dizzy or drowsy, or may cause trouble with thinking or controlling body movements, which may lead to falls, fractures, or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. You may also feel lightheaded when getting up suddenly from a lying or sitting position, so stand up slowly.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, breast cancer, dementia, diabetes, thyroid problems, eye or vision problems (including increased pressure in the eye), an enlarged prostate, trouble urinating, constipation, or a history of seizures, or neuroleptic malignant syndrome (NMS). Tell your doctor if you have any kind of blood vessel or heart problems, including low or high blood pressure, heart failure, heart rhythm problems (including QT prolongation, slow heartbeat), high cholesterol, or a history of heart attack or stroke.

  • This medicine may cause the following problems:Neuroleptic malignant syndrome (a nerve and muscle problem)High blood sugar, cholesterol, or triglyceride levelsTardive dyskinesia (a muscle problem that may become permanent)Changes in blood pressure, especially in childrenEye or vision problems (including cataracts)Heart rhythm problemsIncreased risk of seizuresAnticholinergic effects, when used with other medicines

  • This medicine may cause depression or thoughts of suicide. Make sure family members know about this. Always tell your doctor about any behavior changes, depression, intense feelings, or thoughts of hurting yourself or others.

Seroquel interactions

  • Some medicines can affect how quetiapine works. Tell your doctor if you are using any of the following:Avasimibe, levodopa, methadone, nefazodone, rifampin, St John's wortBlood pressure medicineMedicine for heart rhythm problems (including amiodarone, procainamide, quinidine, sotalol)Medicine for seizures (including carbamazepine, phenobarbital, phenytoin)Medicine to treat an infection (including gatifloxacin, itraconazole, ketoconazole, moxifloxacin, pentamidine)Medicine to treat HIV/AIDS (including indinavir, ritonavir)Other medicine to treat mental health problems (including chlorpromazine, thioridazine, ziprasidone)

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Do not drink alcohol while you are using this medicine.

  • This medicine may make you dizzy, lightheaded, or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel dizzy.

  • This medicine may cause you to get infections easily because it can lower the number of white blood cells. Take precautions to prevent illness. Avoid people who are ill, and wash your hands often.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need to have your eyes tested on a regular basis.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Seroquel side effects

Serious Side Effects

  • Fever, chills, cough, sore throat, body aches

  • Fast, slow, pounding, or uneven heartbeat

  • Constant muscle movement that you cannot control (often in your lips, tongue, jaw, arms, or legs)

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Changes in mood or behavior, agitation, anxiety, restlessness, thoughts of hurting yourself or others

  • Vision changes

  • Increase in how much or how often you urinate, increased thirst, increased hunger, weakness

  • Lightheadedness, dizziness, or fainting, clumsiness

  • Seizures

  • Fever, sweating, confusion, muscle stiffness

Less Serious Side Effects

  • Weight gain

  • Headache

  • Sleepiness

  • Constipation, vomiting, nausea, dry mouth

  • Trouble swallowing