What is Qsymia: Uses, Warnings & Interactions

Updated Jan. 13, 2021  •  Published Dec. 30, 2020

Qsymia overview

BRAND NAMES:

  • Qsymia

Generic Names:

  • Qsymia

Uses:

  • Used with diet and exercise to help you reach and maintain a healthy weight.

Therapeutic Classes:

  • Anticonvulsant, Appetite Suppressant, Centrally Acting

Forms:

  • Long Acting Capsule

How it’s taken:

  • By mouth

What is Qsymia used for?

Qsymia is a medication used – along with a doctor approved weight loss plan – for weight loss. This combination drug contains phentermine (appetite suppressant) and topiramate (an anticonvulsant). Qsymia is a brand version of the combination drug phentermine HCL/topiramate. The components of this drug have been available for years. In the treatment of obesity, Qsymia use is fairly common.

What form(s) does Qsymia come in

  • Long Acting Capsule

What are common Qsymia doses?

  • Capsule 7.5mg/46mg

  • Capsule 3.75mg/23mg

  • Capsule 15mg/92mg

  • Capsule 11.25mg/69mg

Common Qsymia prescriptions

  • Qsymia
    11.25mg/69mg capsule

  • Qsymia
    15mg/92mg capsule

  • Qsymia
    3.75mg/23mg capsule

  • Qsymia
    7.5mg/46mg capsule

How to take Qsymia

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Carefully follow your doctor's instructions about diet and exercise.

  • Take this medicine in the morning, with or without food. It might keep you awake if you take it at night.

  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.

  • Drink extra fluids so you will urinate more often and help prevent kidney problems.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss a dose or forget to take your medicine, skip the missed dose. Take your regular dose the next morning. Do not take extra medicine to make up for the missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Take this medicine in the morning, with or without food. It might keep you awake if you take it at night.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Carefully follow your doctor's instructions about diet and exercise.

  • Drink extra fluids so you will urinate more often and help prevent kidney problems.

  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.

  • Missed dose: If you miss a dose or forget to take your medicine, skip the missed dose. Take your regular dose the next morning. Do not take extra medicine to make up for the missed dose.

Qsymia contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to phentermine or topiramate, you are pregnant, or if you have glaucoma or an overactive thyroid.

Qsymia warnings

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, diabetes, heart failure, heart rhythm problems, or a history of stroke or heart attack.

  • Rarely, this medicine may increase the risk of suicidal thoughts or actions. Tell your doctor if you have a history of depression or suicide attempts.

  • This medicine could cause the following problems: Vision problems or glaucomaMetabolic acidosis (too much acid in the blood)An increased heart rateChanges in blood sugar levelsKidney stones

  • This medicine may cause you to feel dizzy, drowsy, or confused, or to have trouble thinking or speaking. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. You might have a seizure if you stop taking the medicine too fast.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Problems with speech or memory, trouble concentrating, confusion

  • Seizures

  • Thoughts of hurting yourself, depression, anxiety, trouble sleeping

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. You should have a negative pregnancy test before you start taking this medicine and every month during treatment. Tell your doctor right away if you miss a period.

Qsymia interactions

  • Do not use this medicine if you have used an MAO inhibitor (MAOI) within the past 14 days.

  • Some medicines can affect how phentermine/topiramate works. Tell your doctor if you are using the following:Acetazolamide, dichlorphenamide, methazolamide, zonisamideBirth control pillsOther diet pills (including nonprescription or herbal products)Diuretic (water pill)Medicine to treat seizures (such as valproic acid, carbamazepine, phenytoin)

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Do not drink alcohol while you are using this medicine.

  • This medicine may cause you to feel dizzy, drowsy, or confused, or to have trouble thinking or speaking. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. You might have a seizure if you stop taking the medicine too fast.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Qsymia side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bloody or dark urine, sudden back pain, stomach pain, painful urination

  • Decreased sweating, fever, or feeling hot

  • Lightheadedness, dizziness, or fainting

  • Thoughts of hurting yourself, depression, anxiety, trouble sleeping

  • Eye pain, vision changes, seeing halos around lights

  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting

  • Fast, pounding, or uneven heartbeat

  • Seizures

  • Fast breathing, loss of appetite, unusual tiredness

  • Problems with speech or memory, trouble concentrating, confusion

Less Serious Side Effects

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Metallic taste in your mouth, dry mouth

  • Constipation