What is Piperacillin Sod-Tazobactam So: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Piperacillin Sod-Tazobactam So overview

BRAND NAMES:

  • Piperacillin Sodium-Tazobactam Sodium Novaplus, PremierPro Rx Piperacillin and Tazobactam, Zosyn, Zosyn

Generic Names:

  • Piperacillin Sod-Tazobactam So

Uses:

  • Treats infections. The medicine contains a penicillin antibiotic.

Therapeutic Classes:

  • Antibiotic

Forms:

  • Injectable

How it’s taken:

  • By injection

What form(s) does Piperacillin Sod-Tazobactam So come in

  • Injectable

What are common Piperacillin Sod-Tazobactam So doses?

  • Solution Reconstituted 3.375 (3-0.375)GM

  • Solution Reconstituted 4.5 (4-0.5)GM

  • Solution Reconstituted 2.25 (2-0.25)GM

Common Piperacillin Sod-Tazobactam So prescriptions

  • Piperacillin Sod-Tazobactam So
    13.5 (12-1.5)gm solution reconstituted

  • Piperacillin Sod-Tazobactam So
    2.25 (2-0.25)gm solution reconstituted

  • Piperacillin Sod-Tazobactam So
    3-0.375gm solution reconstituted

  • Piperacillin Sod-Tazobactam So
    3.375 (3-0.375)gm solution reconstituted

  • Piperacillin Sod-Tazobactam So
    4.5 (4-0.5)gm solution reconstituted

  • Piperacillin Sod-Tazobactam So
    40.5 (36-4.5)gm solution reconstituted

How to take Piperacillin Sod-Tazobactam So

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be injected slowly, so your IV tube will need to stay in place for at least 30 minutes.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be injected slowly, so your IV tube will need to stay in place for at least 30 minutes.

Piperacillin Sod-Tazobactam So contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to piperacillin, tazobactam, or similar antibiotic medicines.

Piperacillin Sod-Tazobactam So warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, congestive heart failure, cystic fibrosis, or seizures. Tell your doctor if you have a history of allergies or are on a low-salt diet.

  • This medicine may cause the following problems:Serious skin reactionsBleeding problemsNerve problems, including seizuresKidney problemSevere diarrhea

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Piperacillin Sod-Tazobactam So interactions

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Some foods and medicines can affect how piperacillin/tazobactam works. Tell your doctor if you are using any of the following:Methotrexate, probenecidBlood thinner (including heparin, warfarin)Diuretic (water pill)Other medicine to treat an infection (including tobramycin, vancomycin)

  • This medicine may cause the following problems:Bleeding problemsSerious skin reactionsSevere diarrhea

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Piperacillin Sod-Tazobactam So side effects

Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Unusual bleeding, bruising, or weakness

  • Seizures

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

  • Bloody or watery diarrhea, stomach cramps, fever

  • Change in how much or how often you urinate, painful or difficult urination, lower back or side pain

Less Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Headache, trouble sleeping

  • Mild diarrhea, constipation, nausea