What is Lovastatin: Uses, Warnings & Interactions

Updated Jan. 13, 2021  •  Published Dec. 30, 2020

Lovastatin overview

BRAND NAMES:

  • Altoprev, Mevacor

Generic Names:

  • Lovastatin

Uses:

  • Lowers high cholesterol and triglyceride levels. May reduce the risk of heart attack, stroke, and blood vessel problems. This is a statin medicine.

Therapeutic Classes:

  • Antihyperlipidemic

Forms:

  • Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What is Lovastatin used for?

Lovastatin is a medication used to treat high cholesterol. Lovastatin belongs to a class of medications called HMG-CoA reductase inhibitors, commonly referred to as “statins.” Lovastatin is a generic medication also available under the trade name Mevacor sold by Merck & Co. Lovastatin was approved by the Food and Drug Administration in 1987. It was the first drug of its class approved by the FDA. Lovastatin is a very commonly prescribed medication.

What form(s) does Lovastatin come in

  • Tablet

  • Long Acting Tablet

What are common Lovastatin doses?

  • Tablet 10MG

  • Tablet 20MG

  • Tablet 40MG

Common Lovastatin prescriptions

  • Lovastatin
    90 tablets bottle

  • Lovastatin
    10mg tablet

  • Lovastatin
    20mg tablet

  • Lovastatin
    40mg tablet

How to take Lovastatin

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take the tablet with food. Take the extended-release tablet without food.

  • Take the medicine in the evening, unless your doctor tells you otherwise.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take the medicine in the evening, unless your doctor tells you otherwise.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Take the tablet with food. Take the extended-release tablet without food.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Lovastatin contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to lovastatin, if you are pregnant or breastfeeding, or if you have an active liver disease.

Lovastatin warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you have kidney disease, diabetes, thyroid disease, uncontrolled epilepsy, or a history of stroke or heart disease. Tell your doctor if you have a history of liver disease or if you drink alcohol regularly.

  • This medicine may cause the following problems:Severe muscle problems (including myopathy, immune-mediated necrotizing myopathy), especially when used with other medicinesRhabdomyolysis (severe muscle weakness) that could lead to kidney damageLiver problems

  • Tell your doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine if you have major surgery or medical tests, a major injury, or other serious health problems.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Lovastatin interactions

  • Do not use this medicine together with boceprevir, clarithromycin, cobicistat, cyclosporine, erythromycin, gemfibrozil, itraconazole, ketoconazole, nefazodone, posaconazole, telaprevir, telithromycin, voriconazole, or certain medicines to treat HIV/AIDS.

  • Some medicines can affect how lovastatin works. Tell your doctor if you are using any of the following:Amiodarone, cimetidine, colchicine, danazol, diltiazem, dronedarone, niacin (vitamin B3), ranolazine, spironolactone, verapamilBlood thinner (including warfarin)Medicine to treat fungus infections (including fluconazole, voriconazole)Other medicine for lowering cholesterol (including fenofibrate)

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Lovastatin side effects

Serious Side Effects

  • Unusual tiredness

  • Change in how much or how often you urinate

  • Muscle pain, tenderness, or weakness

  • Blistering, peeling, red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

Less Serious Side Effects

  • Headache