What is Atorvastatin Calcium: Uses, Warnings & Interactions

Updated Feb. 16, 2024  •  Published Dec. 30, 2020

Atorvastatin Calcium overview

BRAND NAMES:

  • Lipitor. Atorvaliq

Generic Names:

  • Atorvastatin calcium

Uses:

  • Lowers high cholesterol and triglyceride levels. Reduces the risk of angina, stroke, heart attack, or certain heart and blood vessel problems.

Therapeutic Classes:

  • HMG-CoA reductase inhibitor (statin), antihyperlipidemic

Forms:

  • Tablet, oral suspension (liquid)

How it’s taken:

  • By mouth

What is Atorvastatin Calcium used for?

Atorvastatin reduces the levels of low-density lipoprotein cholesterol (LDL cholesterol) and fats in the bloodstream. It’s prescribed to adults to treat high cholesterol levels, high-fat levels, or both. It’s also used to prevent cardiovascular events (heart attack, chest pain, and stroke) in people with certain risk factors.

What form(s) does Atorvastatin Calcium come in

  • Tablet

    • 10 mg

    • 20 mg

    • 40 mg

  • Oral suspension (liquid)

    • 20 mg/5 mL

What are common Atorvastatin Calcium doses?

  • For high cholesterol in adults (OTC famotidine): 10–80 mg once daily

  • For hereditary high cholesterol in adults and children 10 years of age and older: 10–80 mg once daily

  • For high fat levels in the blood (hypertriglyceridemia) in adults: 10–80 mg once daily

  • For prevention of stroke, heart attack, or angina in adults: 10–80 mg once daily

RELATED: Lipitor dosage, forms, and strengths

Common Atorvastatin Calcium prescriptions

  • Atorvastatin Calcium
    20mg blister of 1 tablet

  • Atorvastatin Calcium
    40mg blister of 1 tablet

  • Atorvastatin Calcium
    30 tablets bottle

  • Atorvastatin Calcium
    30 tablets of 20mg bottle

  • Atorvastatin Calcium
    30 tablets of 40mg bottle

  • Atorvastatin Calcium
    10mg box of 100 tablets

  • Atorvastatin Calcium
    20mg box of 100 tablets

  • Atorvastatin Calcium
    80mg box of 30 tablets

  • Atorvastatin Calcium
    10mg box of 50 tablets

  • Atorvastatin Calcium
    40mg box of 50 tablets

  • Atorvastatin Calcium
    30 tablets disp pack

  • Atorvastatin Calcium
    30 tablets of 10mg dispense pack

  • Atorvastatin Calcium
    30 tablets punchcard

  • Atorvastatin Calcium
    30 tablets of 10mg punchcard

  • Atorvastatin Calcium
    30 tablets of 20mg punchcard

  • Atorvastatin Calcium
    10mg tablet

  • Atorvastatin Calcium
    20mg tablet

  • Atorvastatin Calcium
    40mg tablet

  • Atorvastatin Calcium
    80mg tablet

How to take Atorvastatin Calcium

  • Take your medicine as directed. Your dose may need to be changed to find what works best for you.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take this medicine once per day at any time of day.

  • HOW TO TAKE ATORVASTATIN TABLETS

    • Atorvastatin tablets can be taken with or without food.

    • Swallow the tablet whole. Do not break, crush, or chew it.

    • Store atorvastatin tablets at room temperature in a tightly sealed container.

  • HOW TO TAKE ATORVASTATIN ORAL SUSPENSION

    • Atorvastatin oral suspension must be taken on an empty stomach (more than one hour before a meal or more than two hours after a meal).

    • Shake the bottle well before measuring out a dose.

    • Use a calibrated oral syringe to measure each dose. If one is missing, the pharmacist can provide one.

    • After the bottle is opened, keep the medicine for only 60 days. After 60 days, throw out any unused medicine in the bottle.

    • Store the oral suspension in the original bottle at room temperature.

What to do if you miss a dose of Atorvastatin Calcium

  • Take a missed dose as soon as you remember. If it is less than 12 hours until your next dose, skip the missed dose and take the next dose at the regular time. 

  • Do not take 2 doses of this medicine within 12 hours.

Atorvastatin Calcium contraindications

  • This medicine is not right for everyone. 

  • Do not take atorvastatin if you:

    • Have had an allergic reaction to atorvastatin

    • Have active liver disease

    • Are pregnant or breastfeeding

Atorvastatin Calcium warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Do not breastfeed when taking atorvastatin.

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine, especially before a medical or dental procedure.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you have:

    • Kidney disease

    • A history of liver disease

    • Diabetes

    • An infection

    • Low blood pressure

    • Muscle pain or weakness

    • Seizures

    • Thyroid problems

    • A recent stroke or TIA (transient ischemic attack) 

  • Tell your doctor if you drink alcohol regularly (two drinks a day).

  • This medicine may cause:

    • Muscle pain, muscle weakness, or severe muscle damage which can lead to kidney problems, kidney failure, and possibly death

    • Liver problems

    • Increased blood sugar levels

Atorvastatin Calcium interactions

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medicines, and supplements you are using before taking atorvastatin.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

  • The most serious side effect of atorvastatin is severe and even life-threatening muscle damage. Combining atorvastatin with certain drugs and foods increases the risk of this side effect including:

    • HIV/AIDS and hepatitis C medications

    • Antifungal medications such as ketoconazole and itraconazole

    • Macrolide antibiotics such as erythromycin and clarithromycin

    • A type of anticholesterol drug called fibrates

    • Niacin

    • Cyclosporine

    • Gemfibrozil

    • Colchicine

    • Grapefruit and grapefruit juice

  • Other drugs combined with atorvastatin may also cause problems including:

    • Birth control pills

    • Blood thinners

    • Cimetidine

    • Colchicine

    • Rifampin

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Atorvastatin Calcium side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Unexplained muscle pain, tenderness, or weakness

  • Change in how much or how often you urinate

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Unusual tiredness

  • Fever

  • Blistering, peeling, red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects of atorvastatin:

  • Runny nose, stuffy nose, sore throat

  • Joint pain

  • Diarrhea

  • Pain in the arms, legs, hands, or feet

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