What is Jardiance: Uses, Warnings & Interactions

Medically reviewed by Ashley WongPharm. D.
Licensed Pharmacist
Updated Dec. 21, 2023  •  Published Dec. 30, 2020
Fact Checked

Jardiance overview

BRAND NAMES:

  • Jardiance

Generic Names:

  • Empagliflozin

Uses:

  • Treats Type 2 diabetes. Also lowers the risk of death in patients with Type 2 diabetes and heart or blood vessel problems. Also lowers the risk of hospitalization and cardiovascular death in patients with heart failure or chronic kidney disease.

Therapeutic Classes:

  • Sodium-glucose co-transporter 2 (SGLT2) inhibitor

Forms:

  • Oral tablet

How it’s taken:

  • By mouth

What is Jardiance used for?

Jardiance is approved by the Food and Drug Administration (FDA) to:

  • Lower blood sugar levels in people ages 10 years and older with type 2 diabetes when used together with a healthy diet and regular exercise

  • Reduce the risk of cardiovascular death in adults with type 2 diabetes and cardiovascular disease

  • Reduce the risk of hospitalization and cardiovascular death in adults with heart failure

  • Reduce the risk of worsening kidney damage, hospitalization, and cardiovascular death in adults with chronic kidney disease

It’s important to note that Jardiance should not be used to treat type 1 diabetes because it can increase the risk of diabetic ketoacidosis in this population. Also, It should not be used for certain adults with chronic kidney disease. This includes people with polycystic kidneys or patients who need high levels of immunosuppressive therapy. 

As always, talking with a healthcare provider is the best way to learn more about what Jardiance can treat and to see if it’s the right medication for you.

  • Jardiance is a brand-name medication used to treat type 2 diabetes. 

  • It’s taken once a day in the morning. 

  • Some of the most common side effects of Jardiance include urinary tract infections (UTIs) and yeast infections. 

What form(s) does Jardiance come in

  • Oral tablet

    • 10 mg

    • 25 mg

What are common Jardiance doses?

  • Tablet 10 mg

  • Tablet 25 mg

Common Jardiance prescriptions

  • Jardiance
    15 tablets bottle

  • Jardiance
    30 tablets bottle

  • Jardiance
    45 tablets bottle

  • Jardiance
    7 tablets bottle

  • Jardiance
    90 tablets bottle

  • Jardiance
    9000 tablets bottle

  • Jardiance
    10mg tablet

  • Jardiance
    25mg tablet

How to take Jardiance

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. This medicine is usually taken in the morning.

  • Jardiance can be taken with or without food. 

  • Stop taking Jardiance for at least 3 days if you have a major surgery or procedure planned. Talk with a healthcare professional about when it’s safe to resume Jardiance treatment.

What to do if you miss a dose of Jardiance

  • If you miss a dose of Jardiance, take it as soon as you remember. But never take two doses at the same time to make up for a missed dose.

Jardiance contraindications

  • This medicine is not right for everyone. Do not use it if you’ve had an allergic reaction to empagliflozin or any other ingredients in the drug.

Jardiance warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. For example, sugar can be present in the urine while you’re taking Jardiance. This will show up on a urine test.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, congestive heart failure, high cholesterol, or a history of pancreas problems or genital yeast or urinary tract infections. Tell your doctor if you are on a low-salt diet, if you drink alcohol, or if you are having a surgery or other procedures.

  • You should not take Jardiance if you have type 1 diabetes. Doing so can greatly increase your risk of diabetic ketoacidosis, which is a serious and life-threatening event where you have high ketones and acid in the blood. 

  • Jardiance can cause low blood sugar levels, especially if taken with certain other diabetes medications. This can cause symptoms such as dizziness, sweating, confusion, and shaking. In severe cases, it can cause seizures or fainting. Be sure you know how to treat low blood sugar quickly before you start taking Jardiance. 

  • Additional problems this medicine may cause are:

    • Low blood pressure

    • Kidney problems

    • Increased risk of genital yeast or urinary tract infections

    • Fournier's gangrene (skin or tissue damage of the area between the anus and genitals)

    • Lower leg amputation

Jardiance interactions

  • Some medicines can affect how empagliflozin works. Tell your doctor if you are using any of the following:

    • Diuretic (water pill)

    • Insulin or another diabetes medicine

    • Lithium

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Provide your healthcare provider an updated list of all medications, vitamins, and supplements you take to avoid drug interactions.

Jardiance side effects

Jardiance may cause side effects that range from mild to severe. 

Contact your healthcare provider if you develop any of the following side effects:

  • Low blood pressure: lightheadedness, dizziness, fainting

  • Fournier’s gangrene: pain, tenderness, redness, or swelling of the area between the anus and genitals, fever, unusual tiredness or weakness

  • Low blood sugar: increased hunger, confusion, shaking, trembling, sweating

  • Ketoacidosis: fast or troubled breathing, tiredness, stomach pain, nausea, vomiting

  • Allergic reaction: itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Urinary tract infection (UTI): change in how much or how often you urinate, bloody or cloudy urine, painful or difficult urination, lower back or side pain

Other side effects may include: 

Sources:

Medically reviewed by Ashley WongPharm. D.
Licensed Pharmacist

Ashley Wong, Pharm.D., has worked for healthcare companies where she translated complex drug information into easy-to-understand language for patients. She also served as a Senior Medical Information Specialist at a medical communications company, where she delivered clinically accurate drug information to healthcare providers and patients and compiled adverse event reports in accordance with the FDA's reporting guidelines.

...