What is Glipizide: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Glipizide overview

BRAND NAMES:

  • Glucotrol, Glucotrol XL

Generic Names:

  • Glipizide

Uses:

  • Treats type 2 diabetes.

Therapeutic Classes:

  • Hypoglycemic

Forms:

  • Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What is Glipizide used for?

Glipizide is a medication used to treat type 2 diabetes. Glipizide belongs to a group of medications called sulfonylureas. Glipizide is a generic medication. It is also available under the brand names Glucotrol and Glucotrol XL, both produced by Pfizer. Glipizide first became available in 1984. In the treatment of type 2 diabetes, glipizide use is very common.

What form(s) does Glipizide come in

  • Tablet

  • Long Acting Tablet

What are common Glipizide doses?

  • Tablet 5MG

  • Tablet 10MG

  • Bottle 30 Tablets

  • Bottle 60 Tablets

Common Glipizide prescriptions

  • glipiZIDE
    30 tablets bottle

  • glipiZIDE
    60 tablets bottle

  • glipiZIDE
    10mg tablet

  • glipiZIDE
    2.5mg tablet

  • glipiZIDE
    5mg tablet

How to take Glipizide

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take the regular tablet about 30 minutes before you eat a meal. Take the extended-release tablet with breakfast, unless your doctor tells you differently.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take the regular tablet about 30 minutes before you eat a meal. Take the extended-release tablet with breakfast, unless your doctor tells you differently.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Glipizide contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to glipizide.

Glipizide warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel problems, stomach or bowel problems, adrenal or pituitary gland problems, or G6PD deficiency. Tell your doctor if you drink alcohol.

  • This medicine may cause the following problems:Higher risk of heart or blood vessel problemsLow blood sugar

  • Part of the extended-release tablet may pass in your stool. This is normal.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Glipizide interactions

  • Some medicines can affect how glipizide works. Tell your doctor if you are using any of the following:Aspirin, chloramphenicol, fluconazole, isoniazid, miconazole, niacin, phenytoin, probenecidBirth control pillBeta blocker medicineBlood thinner (including warfarin)Diuretic (water pill)MAO inhibitorMedicine to treat an infection (including ciprofloxacin, levofloxacin, moxifloxacin)NSAID pain or arthritis medicine (including celecoxib, diclofenac, ibuprofen, naproxen)Phenothiazine medicineSteroid medicineSulfa drugThyroid medicine

  • If you are also taking colesevelam, take it at least 4 hours after you take glipizide.

  • Part of the extended-release tablet may pass in your stool. This is normal.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Glipizide side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast or pounding heartbeat, lightheadedness, dizziness

  • Blurred vision, changes in vision

  • Headache or confusion

  • Sweating, trembling, shakiness, increased hunger

Less Serious Side Effects

  • Mild nausea, diarrhea, stomach upset