What is Cilostazol: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Cilostazol overview

BRAND NAMES:

  • Pletal

Generic Names:

  • Cilostazol

Uses:

  • Treats intermittent claudication (a problem with blood flow in the legs) by helping you walk longer distances with less pain.

Therapeutic Classes:

  • Platelet Aggregation Inhibitor

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Cilostazol used for?

Cilostazol is used to treat a leg circulation problem called intermittent claudication. This drug prevents blood clotting by blocking platelet function. Cilostazol also dilates the arteries to improve blood flow. Cilostazol is a medication also sold under the brand name Pletal by Otsuka Pharmaceutical Co. In the treatment of intermittent claudication, cilostazol use is common.

What form(s) does Cilostazol come in

  • Tablet

What are common Cilostazol doses?

  • Tablet 50MG

  • Tablet 100MG

Common Cilostazol prescriptions

  • Cilostazol
    100mg tablet

  • Cilostazol
    50mg tablet

How to take Cilostazol

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine at least 30 minutes before or 2 hours after a meal.

  • Your leg pain may not get better right away. It may take 2 weeks or more before you have improvement and up to 12 weeks for the full effect.

  • Your leg pain may not get better right away. It may take 2 weeks or more before you have improvement and up to 12 weeks for the full effect.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take this medicine at least 30 minutes before or 2 hours after a meal.

Cilostazol contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to cilostazol or if you have heart failure.

Cilostazol warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Unusual bleeding, bruising, or weakness

  • This medicine may cause the following problems:Heart rhythm problemsHeart problemsDecrease in number of blood cells, which may lead to bleeding or infectionsLow blood pressure

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bleeding problems, blood clotting problems, angina, or a history of heart disease.

Cilostazol interactions

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Some foods and medicines can affect how cilostazol works. Tell your doctor if you are using clarithromycin, diltiazem, erythromycin, fluconazole, indinavir, itraconazole, ketoconazole, nelfinavir, omeprazole, ritonavir, telithromycin, or ticlopidine.

Cilostazol side effects

Serious Side Effects

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast, pounding, or uneven heartbeat

  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating

  • Fever, chills, cough, sore throat, body aches

  • Lightheadedness, dizziness, or fainting

Less Serious Side Effects

  • Diarrhea

  • Swelling in the hands, ankles, or feet

  • Headache

  • Stuffy or runny nose