Amitiza Coupons & Prices

Amitiza is used to treat chronic constipation, constipation caused by opioid pain medicine, and irritable bowel syndrome with constipation (IBS-C). Amitiza is a brand-name prescription medication used to increase fluids in your intestines to make it easier to have bowel movements. Lubipros

10 Capsule8mcgEdit

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Amitiza coupon at Walgreens Pharmacy
$57.27
$ 54.27
  • How is this calculated?

  • Price if you don’t sign up:

    $57.27

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $54.27

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Amitiza coupon at Walmart Neighborhood Market Pharmacy
$70.77
$ 67.77
  • How is this calculated?

  • Price if you don’t sign up:

    $70.77

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $67.77

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Amitiza coupon at Walmart Pharmacy
$70.77
$ 67.77
  • How is this calculated?

  • Price if you don’t sign up:

    $70.77

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $67.77

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Amitiza coupon at Costco Pharmacy
$ 81.99
Amitiza coupon at Rite Aid Pharmacy
$100.65
$ 97.65
  • How is this calculated?

  • Price if you don’t sign up:

    $100.65

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $97.65

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
Amitiza coupon at Cvs Pharmacy
$106.04
$ 103.04
  • How is this calculated?

  • Price if you don’t sign up:

    $106.04

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $103.04

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$106.83
$ 103.83
  • How is this calculated?

  • Price if you don’t sign up:

    $106.83

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $103.83

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$106.83
$ 103.83
  • How is this calculated?

  • Price if you don’t sign up:

    $106.83

  • One-time signup bonus

    -$3.00

  • Price with free signup

    $103.83

  • Signup bonus and member savings are automatically applied to your price when you fill an eligible prescription.

  • Sign up for free
Price with signup$3 off with signupwith signup
$ 122.00

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 sign-up bonus, may only be used once.

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About Lubiprostone

Amitiza is used to treat chronic constipation, constipation caused by opioid pain medicine, and irritable bowel syndrome with constipation (IBS-C). Amitiza is a brand-name prescription medication used to increase fluids in your intestines to make it easier to have bowel movements. Lubiprostone is the generic name of and active ingredient in Amitiza. The retail price of Amitiza is $485.40 for 60, 8MCG Capsule. Save money and pay a reduced price of $54.27 for 60, 24mcg Capsule of generic Amitiza with a coupon from SingleCare. Our coupons are always free, reusable, and accepted at many major pharmacies.

Amitiza Price History & Information

Price History for Amitiza

60 count, 24mcg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 12 Month Prices for Amitiza

60 count, 24mcg
PharmacyAmitiza Retail PriceAmitiza SingleCare Price
CVS Pharmacy$325.92$123.01
Walmart$379.91$111.29
Walgreens$308.40$146.72
Kroger Pharmacy$400.91$194.40
Albertsons Pharmacy$384.00$240.30
Rite Aid Pharmacy$499.80$96.37

These prices are based on the last 12 months of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Amitiza

Amitiza is used to treat chronic constipation, constipation caused by opioid pain medicine, and irritable bowel syndrome with constipation (IBS-C). Amitiza is a brand-name prescription medication used to increase fluids in your intestines to make it easier to have bowel movements. Lubiprostone is the generic name of and active ingredient in Amitiza. The retail price of Amitiza is $485.40 for 60, 8MCG Capsule. Save money and pay a reduced price of $54.27 for 60, 24mcg Capsule of generic Amitiza with a coupon from SingleCare. Our coupons are always free, reusable, and accepted at many major pharmacies.

Amitiza FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Amitiza cost without insurance?

If you do not have insurance, Amitiza costs $485.40 per 60, 8MCG Capsule, if not more. Luckily, you can save on prescription costs by using SingleCare's Amitiza coupon. When you use our discount card at local pharmacies, you can pay our lowest price of $54.27 for 60, 24mcg Capsule of generic Amitiza.

How much does Amitiza cost with insurance?

The insured cost of Amitiza varies across insurance plans. If you're underinsured, you can sign up to use a SingleCare savings card to fill your Amitiza prescription at a discounted price that could be cheaper than your insurance copay. Amitiza costs $54.27 for 60, 24mcg Capsule of generic Amitiza with SingleCare. Ask your local pharmacist to review your copay with insurance versus SingleCare to save on your next refill. You can always contact your insurance company for more information or questions about the cost. 

Does Medicare cover Amitiza and how much does it cost?

Medicare prescription plans typically cover generic Amitiza. Many SingleCare customers have reportedly saved more on their prescription drugs when using our card over Medicare and other insurance plans. That's because the cash prices of prescription drugs are sometimes cheaper than what your insurance offers. Apply one of our free coupons on top of that already-low price to get the maximum Amitiza discount.

How to save on Amitiza

To save on Amitiza, patients can register for a free pharmacy benefit card from SingleCare. Search our website or app to find a pharmacy near you with the lowest price available for Amitiza. With a SingleCare Amitiza, you could pay as low as $54.27 for 60, 24mcg Capsule for your prescription. 

Is there a generic of Amitiza?

Amitiza is a brand name for lubiprostone that is manufactured by Takeda Pharmaceuticals North America, Inc. There are several generic versions of Amitiza currently available and approved by the FDA in the United States.

What is Amitiza?

Amitiza is a member of the chloride channel activators drug class. This drug should not be mistaken for a laxative or a fiber. Amitiza helps to enhance the body's natural function by increasing fluid in the bowels to help you pass stool. Amitiza works locally in the intestines to regulate the fluid balance so you can avoid constipation. Amitiza does not alter electrolyte concentrations or produce tolerance as is sometimes seen with laxatives.

Amitiza is available in oral capsules and is supplied in 60, 8MCG Capsule. Amitiza is generally prescribed to be used twice daily for chronic idiopathic constipation (CIC) in adults, constipation caused by opioid pain medication, or for irritable bowel syndrome with constipation (IBS-C). Amitiza is an FDA-approved drug that can only be used by adults.

For IBS-C, Amitiza is only approved for use in adult women.

Amitiza should be taken with food and water. You should swallow the capsule whole and do not try to crush, chew, break, or open it. 

You should seek medical advice if you have liver problems, if you suspect you have a bowel blockage, or if you are taking a diphenylheptane opioid such as methadone. You should not take Amitiza if you have severe diarrhea, as Amitiza can cause diarrhea.

What are the side effects of Amitiza?

Some common side effects of Amitiza that people experience include diarrhea, nausea, vomiting, gas, indigestion, bloating, and abdominal pain. Although this is not a full list of possible side effects, using Amitiza may also result in a sore throat, headache, dizziness, swelling, back and joint pain, runny nose, and tiredness.

While an allergic reaction to Amitiza is rare, if you have symptoms such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, you should get emergency medical help immediately. 

Consult your healthcare professional regarding more information about side effects. 

Individuals with a bowel blockage, severe diarrhea, or liver problems, should tell their healthcare provider so they can determine if your dosage of Amitiza needs to be adjusted or changed.

Can Amitiza be taken with other medications?

Amitiza interacts with various medications. Before taking Amitiza, review your medication list with your healthcare provider, making sure to include all of the prescription and over-the-counter drugs, vitamins, and supplements you take. Examples of drug interactions with Amitiza include:

  • Blood pressure medications such as Altace (ramipril), Norvasc (amlodipine), or Tenormin (atenolol) 

  • Diuretics like hydrochlorothiazide or Lasix (furosemide)

  • Opioid pain medications such as oxycodone or methadone

  • Prostate medications like Flomax (tamsulosin) or Uroxatral (alfuzosin)

  • Tricyclic antidepressants such as Elavil (amitriptyline) or Pamelor (nortriptyline)

This is not a full list of drug interactions and others may occur.

Is there an alternative for Amitiza? 

Some prescription drug alternatives for Amitiza include:

  • Bentyl (dicyclomine)

  • Lactulose 

  • Linzess (linaclotide)

  • Motegrity (prucalopride)

  • Trulance (plecanatide)

  • Zelnorm (tegaserod): This drug is only available to treat women, not men, and can only be prescribed through a special program due to its potentially serious side effects.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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