What is Zomig: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 31, 2020

Zomig overview

BRAND NAMES:

  • Zomig, Zomig-ZMT, Zomig

Generic Names:

  • Zolmitriptan

Uses:

  • Treats migraine headaches., Treats migraine headaches. This medicine does not prevent migraine headaches. This medicine is a triptan.

Therapeutic Classes:

  • Antimigraine, Antimigraine

Forms:

  • Spray, Tablet, Dissolving Tablet

How it’s taken:

  • By mouth, Into the nose

What form(s) does Zomig come in

  • Spray

  • Tablet

  • Dissolving Tablet

What are common Zomig doses?

  • Box 6 Tablets

  • Box 3 Tablets

  • Box 6 Solution

Common Zomig prescriptions

  • Zomig
    3 tablets bottle

  • Zomig
    3 tablets box

  • Zomig
    6 solution box

  • Zomig
    6 tablets box

  • Zomig
    5mg tablet

How to take Zomig

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • If your headache does not get any better after 1 dose of medicine, you may use 1 additional dose of zolmitriptan if at least 2 hours have passed after the first dose. Do not use more than 2 doses in any 24-hour period.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Keep the orally disintegrating tablet in the blister pack inside the outer foil pouch until you are ready to take the medicine. Make sure your hands are dry and peel open the blister to remove the tablet. Do not break the tablet. Place the tablet on your tongue and let it dissolve. You do not need to drink water to swallow the dissolved tablet.

  • If your headache does not get any better after 1 dose of medicine, you may use 1 additional dose of zolmitriptan if at least 2 hours have passed after the first dose. Do not use more than 2 doses in any 24-hour period.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Keep the orally disintegrating tablet in the blister pack inside the outer foil pouch until you are ready to take the medicine. Make sure your hands are dry and peel open the blister to remove the tablet. Do not break the tablet. Place the tablet on your tongue and let it dissolve. You do not need to drink water to swallow the dissolved tablet.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light.

  • Use zolmitriptan only when you have a migraine. This medicine is not used on a regular schedule.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Keep your head tilted back and remove the spray unit from your nose. Breathe through your mouth for 5 to 10 seconds. You might feel some liquid in your nose or on the back of your throat.

  • Hold 1 nostril closed with your finger. Place the tip of the spray unit in your other nostril. Breathe in gently through your nose and slowly release 1 spray into your nose at the same time.

  • Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.

  • Do not prime the nasal spray. The unit contains only enough medicine for 1 spray.

  • Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

  • If your headache comes back or you do not get complete relief, wait at least 2 hours before you take another dose. Do not use more than 10 milligrams (mg) in 24 hours.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.

  • If your headache comes back or you do not get complete relief, wait at least 2 hours before you take another dose. Do not use more than 10 milligrams (mg) in 24 hours.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Keep your head tilted back and remove the spray unit from your nose. Breathe through your mouth for 5 to 10 seconds. You might feel some liquid in your nose or on the back of your throat.

  • Do not prime the nasal spray. The unit contains only enough medicine for 1 spray.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light.

  • Use zolmitriptan only when you have a migraine. This medicine is not used on a regular schedule.

  • Hold 1 nostril closed with your finger. Place the tip of the spray unit in your other nostril. Breathe in gently through your nose and slowly release 1 spray into your nose at the same time.

What to do if you miss a dose of Zomig

  • Use zolmitriptan only when you have a migraine. This medicine is not used on a regular schedule.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Zomig contraindications

  • Do not use this medicine if you have had an allergic reaction to zolmitriptan or if you have heart disease, blood vessel disease, or circulation problems. Do not use this medicine if you have high blood pressure that is not under control or a history of heart disease, heart attack, angina, heart rhythm problem, stroke, transient ischemic attack (TIA), or ischemic bowel disease. Do not use this medicine for hemiplegic or basilar migraine headaches. Do not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine, tranylcypromine, Nardil®, or Parnate® within the past 14 days. Do not use this medicine if you have taken another migraine headache medicine in the past 24 hours, such as another triptan or an ergot medicine. These medicines include almotriptan (Axert„¢), dihydroergotamine (D.H.E. 45®, Migranal®), eletriptan (Relpax®), ergotamine (Cafergot®, Ergomar®, Wigraine®), frovatriptan (Frova®), rizatriptan (Maxalt®), or sumatriptan (Imitrex®, Treximet®).

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to zolmitriptan. Tell your doctor if you have heart or blood vessel problems, such as a history of heart attack or stroke, or if you have heart rhythm problems.

Zomig warnings

  • This medicine may make you dizzy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.

  • The orally disintegrating tablet contains phenylalanine. Tell your doctor if you have phenylketonuria (PKU) before you use this form of zolmitriptan.

  • Make sure your doctor knows if you are pregnant or breastfeeding or if you have kidney disease, liver disease, high blood pressure, or a family history of heart disease. Tell your doctor if you have a history of stomach or bowel bleeding, Raynaud disease, or other blood flow problems.

  • This medicine should be used only for classic or common migraine headaches. It should not be used to treat any other kind of headache or pain.

  • This medicine can cause heart problems, including heart attack. This is more likely to happen if you already have heart disease. Tell your doctor if you have any risk factors for heart disease, such as high blood pressure, smoking, diabetes, or a family history of heart disease or stroke.

  • Check with your doctor right away if you have chest discomfort, jaw or neck tightness after you take this medicine. Also tell your doctor if you have sudden or severe stomach pain or bloody diarrhea after you use this medicine. Tell your doctor if you have any changes in vision that are not part of your usual migraine.

  • Your headaches may become worse if you use zolmitriptan alone or in combination with other migraine medicines for 10 or more days per month. Keep a headache diary to record your headache frequency and drug use.

  • This medicine may cause a serious condition called serotonin syndrome when taken with certain medicines. Call your doctor right away if you have a fever, confusion, mental changes, restlessness, fast heartbeat, muscle spasms, trouble walking, nausea, vomiting, or diarrhea.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Tightness or discomfort in your chest, neck, or jaw

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine may make you dizzy, weak, or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your headaches may become worse if you use headache medicine for 10 or more days per month.

  • This medicine may cause the following problems:Higher risk for abnormal heart rhythm, heart attack, angina, or strokeTightness or discomfort in your chest, neck, or jawSpasms in the blood vessels, such as Raynaud syndromeSerotonin syndromeIncreased blood pressure

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, diabetes, high blood pressure, high cholesterol, or a family history of heart disease. Tell your doctor if you have a history of blood circulation problems or if you smoke.

  • This medicine should be used only for classic or common migraine headaches. Do not use for any other kind of headache or pain.

  • Vision changes that are not part of a usual migraine

Zomig interactions

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine may make you dizzy, weak, or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may cause the following problems:Higher risk for abnormal heart rhythm, heart attack, angina, or strokeTightness or discomfort in your chest, neck, or jawSpasms in the blood vessels, such as Raynaud syndromeSerotonin syndromeIncreased blood pressure

  • Your headaches may become worse if you use headache medicine for 10 or more days per month.

  • Some foods and medicines can affect how zolmitriptan works. Tell your doctor if you are using cimetidine or medicine for depression.

  • Do not use this medicine if you have taken another migraine headache medicine in the past 24 hours, such as another triptan or an ergot medicine. These medicines include almotriptan, dihydroergotamine, eletriptan, ergotamine, frovatriptan, methysergide, rizatriptan, or sumatriptan. Do not use this medicine if you have taken an MAO inhibitor (such as phenelzine, tranylcypromine) in the past 14 days.

  • Make sure your doctor knows if you use cimetidine (Tagamet®) or a medicine for depression (such as amitriptyline, citalopram, fluoxetine, nortriptyline, sertraline, Cymbalta®, Effexor®, Elavil®, Lexapro®, Pristiq®).

  • This medicine should be used only for classic or common migraine headaches. It should not be used to treat any other kind of headache or pain.

  • This medicine can cause heart problems, including heart attack. This is more likely to happen if you already have heart disease. Tell your doctor if you have any risk factors for heart disease, such as high blood pressure, smoking, diabetes, or a family history of heart disease or stroke.

  • Check with your doctor right away if you have chest discomfort, jaw or neck tightness after you take this medicine. Also tell your doctor if you have sudden or severe stomach pain or bloody diarrhea after you use this medicine. Tell your doctor if you have any changes in vision that are not part of your usual migraine.

  • Your headaches may become worse if you use zolmitriptan alone or in combination with other migraine medicines for 10 or more days per month. Keep a headache diary to record your headache frequency and drug use.

  • This medicine may cause a serious condition called serotonin syndrome when taken with certain medicines. Call your doctor right away if you have a fever, confusion, mental changes, restlessness, fast heartbeat, muscle spasms, trouble walking, nausea, vomiting, or diarrhea.

  • This medicine may make you dizzy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.

  • The orally disintegrating tablet contains phenylalanine. Tell your doctor if you have phenylketonuria (PKU) before you use this form of zolmitriptan.

  • Call your doctor if your symptoms do not improve or if they get worse.

Zomig side effects

Serious Side Effects

  • Tightness or discomfort in your chest, neck, or jaw

  • Fast or uneven heartbeat

  • Sudden severe headache (other than the one being treated)

  • Severe stomach pain, bloody diarrhea, nausea, or vomiting

  • Chest pain, especially if it spreads to your arms, jaw, back, or neck

  • Anxiety, restlessness, fever, sweating, muscle spasms, twitching, diarrhea, seeing or hearing things that are not there

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Vision changes that are not part of a usual migraine

  • Numbness or tingling in your hands, arms, legs, or feet, color changes in your fingers or toes

  • Chest pain, especially if it spreads to your arms, jaw, back, or neck

  • Vision changes that are not part of a usual migraine

  • Severe stomach pain, bloody diarrhea, vomiting, nausea, fever

  • Fast or uneven heartbeat

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever, confusion, mental changes, restlessness, muscle spasms, trouble walking

  • Sudden severe headache (other than the one being treated)

  • Numbness or tingling in your hands, arms, legs, or feet

  • Tightness or discomfort in your chest, neck, or jaw

Less Serious Side Effects

  • Feeling dizzy, drowsy, weak, or tired

  • Feeling dizzy

  • Bad or unusual taste in your mouth