Remeron, Remeron Soltab
Mirtazapine
Treats depression
Antidepressant, atypical antidepressant
Tablet, orally dissolving tablet
By mouth
Mirtazapine is a medication used to treat depression.
Tablet
7.5 mg
15 mg
30 mg
45 mg
Orally disintegrating tablet
15 mg
30 mg
45 mg
For depression in adults: 15–45 mg daily (preferably at bedtime)
Mirtazapine
15mg tablet
Mirtazapine
30mg tablet
Mirtazapine
45mg tablet
Mirtazapine
7.5mg tablet
Mirtazapine
15mg tablet disintegrating
Mirtazapine
30mg tablet disintegrating
Mirtazapine
45mg tablet disintegrating
Take your medicine as directed. The dose may need to be changed several times to find what works best for you.
Take mirtazapine tablets only once per day.
The preferred time to take doses is before bedtime because mirtazapine can make people sleepy.
Mirtazapine can be taken with or without food.
You may need to take this medicine for several weeks before you begin to feel better.
Please read the Medication Guide that comes with this medicine. If it’s missing, a pharmacist can supply a copy.
How to take mirtazapine tablets
Swallow the tablet whole with a drink of water.
Store mirtazapine tablets at room temperature away from light and moisture.
How to take mirtazapine orally disintegrating tablets
Make sure your hands are dry before you handle the disintegrating tablet.
Peel back the foil from the blister pack, then gently remove the tablet.
Do not push the tablet through the foil.
You must immediately use a tablet if you remove it from the blister pack.
Place the tablet whole on your tongue.
Allow it to completely melt. Do not crush, break, or chew it.
Once it has melted, it can be swallowed with saliva. There is no need to drink water.
Store mirtazapine orally disintegrating tablets at room temperature, protected from light and moisture.
Take one dose of mirtazapine each day.
If a dose is missed, take the dose as soon as it’s remembered. If it’s the next day, skip the missed dose. Instead, take the next dose at the time it’s normally taken.
Do not take an extra dose to make up for a missed dose.
This medicine is not right for everyone.
Do not use it if you have had an allergic reaction to mirtazapine.
Tell any doctor or other healthcare provider who treats you that you are using this medicine.
Your doctor will do lab tests regularly to check on the effects of this medicine. Keep all appointments.
For some children, teenagers, and young adults, this medicine increases the risk of suicidal thoughts and behaviors. It may worsen depression or emotional problems. Talk with your doctor right away if you notice any thoughts or behavior changes that concern you.
Tell your doctor if you or anyone in your family has a history of bipolar disorder, mania, hypomania, other mental illnesses, or suicide attempts.
Tell your doctor if you are pregnant or breastfeeding.
Tell your doctor if you have:
Liver disease
Kidney disease
A history of heart problems or stroke
An abnormal heart rhythm called QT prolongation
Seizures
Glaucoma
Low white blood cell counts
High cholesterol
Low sodium
Low blood pressure
Phenylketonuria
This medicine may cause the following problems:
Serotonin syndrome
Decreased white blood cells, which can affect your body's ability to fight an infection
Low sodium levels in the blood
Heart rhythm abnormalities
Angle-closure glaucoma
Increased cholesterol or fats in the blood
Low sodium
Manic episodes
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use before taking amitriptyline.
Tell other healthcare providers you are using this medicine before they prescribe new medications.
Do not use this medicine and an MAO inhibitor (MAOI) within 14 days of each other.
Some medicines and foods can affect how mirtazapine works or increase the risk or severity of side effects. Tell your doctor if you are taking:
Other antidepressants
Any other drug used to treat mental illness
Migraine drugs called triptans
Benzodiazepines, a type of sedative that treats anxiety and seizures
Amphetamines
Heart rhythm drugs
Macrolide antibiotics such as azithromycin
The anticonvulsants phenytoin or carbamazepine
The narcotic painkillers fentanyl or tramadol
The tuberculosis treatment rifampin
The blood thinner warfarin
Lithium
Cimetidine, an over-the-counter heartburn drug or prescription ulcer drug
The supplements tryptophan or St. John’s wort
Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
Avoid drinking alcohol when using mirtazapine.
Find more detailed information about mirtazapine interactions to avoid here.
Serious side effects
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:
Thoughts of hurting yourself or others, worsening depression, unusual behaviors
Fever, chills, cough, sore throat, body aches, and other signs of infection
Eye pain, sudden vision changes, seeing halos around lights
Confusion, weakness, muscle twitching
Feeling more excited or energetic than usual, racing thoughts, euphoric mood
Seizures
Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, rigid muscles, seeing or hearing things that are not there
Blistering, peeling, red skin rash
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Drowsiness
Dizziness
Dry mouth
Increased appetite
Weight gain
High cholesterol
Constipation
Find more detailed information about mirtazapine side effects here.
Mirtazapine orally disintegrating tablet prescribing information, DailyMed (NIH National Library of Medicine)
Mirtazapine tablet prescribing information, DailyMed (NIH National Library of Medicine)
Remeron | Remeronsoltab prescribing information, DailyMed (NIH National Library of Medicine)
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