What is Midodrine Hcl: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 30, 2020

Midodrine Hcl overview

Generic Names:

  • Midodrine Hcl

Uses:

  • Treats a kind of low blood pressure that can cause severe dizziness or fainting.

Therapeutic Classes:

  • Vasopressor

Forms:

  • Tablet

How it’s taken:

  • By mouth

What form(s) does Midodrine Hcl come in

  • Tablet

What are common Midodrine Hcl doses?

  • Tablet 2.5MG

  • Tablet 5MG

  • Tablet 10MG

Common Midodrine Hcl prescriptions

  • Midodrine HCl
    10mg tablet

  • Midodrine HCl
    2.5mg tablet

  • Midodrine HCl
    5mg tablet

How to take Midodrine Hcl

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take the missed dose as soon as possible, unless you are due to take your next dose within 3 hours. Do not use extra medicine to make up for a missed dose.

  • Lying down after taking this medicine may cause your blood pressure to get too high. Do not take the last dose of the day after 6 pm or after the evening meal, and be sure you wait at least 4 hours after the last dose before going to bed.

  • Your doctor may tell you to take this medicine in the morning, at noon, and in the late afternoon. Wait at least 4 hours between each dose of this medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Lying down after taking this medicine may cause your blood pressure to get too high. Do not take the last dose of the day after 6 pm or after the evening meal, and be sure you wait at least 4 hours after the last dose before going to bed.

  • Your doctor may tell you to take this medicine in the morning, at noon, and in the late afternoon. Wait at least 4 hours between each dose of this medicine.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Missed dose: Take the missed dose as soon as possible, unless you are due to take your next dose within 3 hours. Do not use extra medicine to make up for a missed dose.

What to do if you miss a dose of Midodrine Hcl

  • You should not use two doses at the same time.

  • Take the missed dose as soon as possible, unless you are due to take your next dose within 3 hours.

  • Skip the missed dose if you are due to take your next dose within 3 hours.

Midodrine Hcl contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to midodrine, or if you have severe organic heart disease, an overactive thyroid, problems emptying your bladder, high blood pressure, or pheochromocytoma.

Midodrine Hcl warnings

  • If you have been taught to check your blood pressure yourself, check it on a regular schedule. Your blood pressure should stay within a certain range. Your doctor will tell you what that range should be. If your blood pressure is out of that range, call your doctor.

  • This medicine will raise your blood pressure. Your blood pressure may get too high, especially when you lie down. Your doctor may want you to sleep with the head of your bed raised to help prevent this.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, glaucoma, or trouble urinating.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. You will need to have your blood pressure checked regularly.

Midodrine Hcl interactions

  • Some diet pills and over-the-counter cold and hay fever medicines can also raise your blood pressure. Talk to your doctor before taking these or any other medicines.

  • Tell your doctor if you are taking digoxin (Lanoxin®) or beta blockers (such as atenolol, metoprolol, propranolol, timolol, Lopressor®, or Tenormin®). If your heart beats become slower or if you feel dizzy while taking midodrine, tell your doctor.

  • Some medicines can affect how midodrine works. Tell your doctor if you are using any of the following:Cimetidine, digoxin, dihydroergotamine, droxidopa, flecainide, fludrocortisone acetate, metformin, procainamide, quinidine, ranitidine, or triamtereneBlood pressure medicine (including doxazosin, prazosin, terazosin)Cold and allergy medicine (including ephedrine, phenylephrine, phenylpropanolamine, pseudoephedrine)Diet pillMAO inhibitor (MAOI)Thyroid supplement

  • If you have been taught to check your blood pressure yourself, check it on a regular schedule. Your blood pressure should stay within a certain range. Your doctor will tell you what that range should be. If your blood pressure is out of that range, call your doctor.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. You will need to have your blood pressure checked regularly.

Midodrine Hcl side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Changes in vision

  • Chest pain

  • Difficult or painful urination, burning while urinating

  • Fast, slow, or pounding heartbeat

Less Serious Side Effects

  • Tingling or itching, especially on your scalp.

  • Goosebumps

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • Urinating more often than usual or feeling the urge to urinate more often.