What is Lotronex: Uses, Warnings & Interactions

Updated Jan 13, 2021  •  Published Dec 31, 2020

Lotronex overview

BRAND NAMES:

  • Lotronex

Generic Names:

  • Alosetron Hcl

Uses:

  • Treats irritable bowel syndrome (IBS).

Therapeutic Classes:

  • Antidiarrheal, Gastrointestinal Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Lotronex used for?

Lotronex is prescribed to women with severe irritable bowel syndrome (IBS) with diarrhoea. Lotronex control bowel movements in women whose IBS symptoms have lasted 6 months or longer and have not been helped enough by other treatments.

What form(s) does Lotronex come in

  • Tablet

What are common Lotronex doses?

  • Tablet 0.5MG

  • Tablet 1MG

Common Lotronex prescriptions

  • Lotronex
    0.5mg tablet

  • Lotronex
    1mg tablet

How to take Lotronex

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Skip the missed dose and go back to your regular dosing schedule. Do not double doses.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Lotronex contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to alosetron, or if you have constipation, a bowel disease (such as a blockage, colitis, Crohn disease, or diverticulitis), or a history of blood clots.

Lotronex warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or other stomach or bowel problems.

  • This medicine may cause the following problems:Severe constipationIschemic colitis

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Lotronex interactions

  • Do not use alosetron if you are also using fluvoxamine.

  • Some medicines can affect how alosetron works. Tell your doctor if you are using any of the following: CimetidineMedicine to treat an infection (including clarithromycin, itraconazole, ketoconazole, telithromycin, voriconazole, or a quinolone antibiotic)Protease inhibitor medicine to treat HIV infection

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Lotronex side effects

Serious Side Effects

  • Red or black stools

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Constipation

  • New or worsening stomach pain or cramps