What is Glycopyrrolate: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Glycopyrrolate overview

BRAND NAMES:

  • Cuvposa, Glycate, Robinul, Robinul Forte

Generic Names:

  • Glycopyrrolate

Uses:

  • Treats peptic ulcers. Also used to treat severe drooling caused by certain conditions (such as cerebral palsy) in children 3 to 16 years of age.

Therapeutic Classes:

  • Cholinergic Antagonist, Gastrointestinal Agent

Forms:

  • Liquid, Tablet

How it’s taken:

  • By mouth

What is Glycopyrrolate used for?

Robinul is used with other drugs to treat peptic ulcers. It may help relieve stomach/abdominal pain. Robinul works by decreasing the amount of acid in the stomach.

What form(s) does Glycopyrrolate come in

  • Liquid

  • Tablet

What are common Glycopyrrolate doses?

  • Tablet 1MG

  • Tablet 2MG

  • Vial 1ML of 0.2MG/ML

  • Vial 2ML of 0.4MG/2ML

  • Vial 5ML of 1MG/5ML

  • Vial 20ML of 4MG/20ML

  • Jar 1GM of

  • Jar 5GM of

  • Bottle 1GM of

Common Glycopyrrolate prescriptions

  • Glycopyrrolate
    473ml of 1mg/5ml bottle

  • Glycopyrrolate
    1.5mg tablet

  • Glycopyrrolate
    1mg tablet

  • Glycopyrrolate
    2mg tablet

  • Glycopyrrolate
    1ml of 0.2mg/ml vial

  • Glycopyrrolate
    20ml of 4mg/20ml vial

  • Glycopyrrolate
    2ml of 0.4mg/2ml vial

  • Glycopyrrolate
    5ml of 1mg/5ml vial

How to take Glycopyrrolate

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • You or your child should take the oral liquid at least one hour before or two hours after meals.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • You or your child should take the oral liquid at least one hour before or two hours after meals.

What to do if you miss a dose of Glycopyrrolate

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Glycopyrrolate contraindications

  • You should not use this medicine if you have had an allergic reaction to glycopyrrolate, or if you have glaucoma, myasthenia gravis, or trouble urinating because of an enlarged prostate or other blockage. You should not use this medicine if you have certain problems with digestion, including severe colitis or something physically blocking digestion. Do not take this medicine if you or your child is receiving potassium chloride tablets or other potassium supplements (in capsule or tablet forms).

Glycopyrrolate warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you or your child has kidney disease, liver disease, heart disease, congestive heart failure, heart rhythm problems, high blood pressure, nerve problems, an enlarged prostate, or an overactive thyroid. Tell your doctor if you or your child has hiatal hernia, heartburn, diarrhea, colitis, a colostomy or ileostomy, or any other problems with your stomach, bowel, or digestive system.

  • This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor right away if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.

  • Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.

  • If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

  • Be careful during hot weather or exercising. This medicine may make you or your child sweat less, so you could get overheated more easily.

  • This medicine may make you drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child is not alert.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Muscle weakness or stiffness.

  • Trouble with breathing.

  • Warmth or redness in your face, neck, arms, or upper chest.

Glycopyrrolate interactions

  • This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor right away if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.

  • Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.

  • If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

  • Make sure your doctor knows if you or your child is receiving amantadine (Symmetrel®), atenolol (Tenormin®), digoxin (Lanoxin®), haloperidol (Haldol®), metformin (Glucophage®), or levodopa (Sinemet®).

  • Be careful during hot weather or exercising. This medicine may make you or your child sweat less, so you could get overheated more easily.

  • This medicine may make you drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child is not alert.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Glycopyrrolate side effects

Serious Side Effects

  • Warmth or redness in your face, neck, arms, or upper chest.

  • Lightheadedness or fainting.

  • Muscle weakness or stiffness.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Abdominal pain or swelling.

  • Decrease in how much or how often you urinate, painful urination.

  • Diarrhea or constipation.

  • Fast or pounding heartbeat.

  • Fever, chills, cough, sore throat, stuffy or runny nose, and body aches.

  • Trouble with breathing.

Less Serious Side Effects

  • Dry mouth.

  • Nasal congestion.

  • Flushing.

  • Light bothering your eyes.

  • Confusion, nervousness.