What is Dexamethasone: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Dexamethasone overview

BRAND NAMES:

  • ZCORT 7-Day, Hemady, TaperDex 7-Day, Dxevo, TaperDex, Decadron, Dexabliss 11-Day Dose Pack, DexPak, DexPak 10 Day TaperPak, DexPak 13 Day TaperPak, DexPak 6 Day TaperPak, HiDex

Generic Names:

  • Dexamethasone

Uses:

  • Treats inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems. May also be used to decrease some symptoms of cancer, including multiple myeloma. This medicine is a corticosteroid.

Therapeutic Classes:

  • Antiemetic, Diagnostic Agent, Adrenocortical Function, Endocrine-Metabolic Agent, Immune Suppressant

Forms:

  • Liquid, Tablet

How it’s taken:

  • By mouth

What is Dexamethasone used for?

Dexamethasone is available in an injectable solution and is used to treat many different inflammatory disorders such as Addison's Disease, Adrenal Insufficiency, Adrenocortical Insufficiency and others. You should not use Dexamethasone if you have a fungal infection anywhere in your body.

What form(s) does Dexamethasone come in

  • Liquid

  • Tablet

What are common Dexamethasone doses?

  • Tablet 0.5MG

  • Tablet 0.75MG

  • Tablet 1MG

  • Tablet 1.5MG

  • Tablet 2MG

  • Tablet 4MG

  • Tablet 6MG

  • Bottle 1GM of

  • Bottle 237ML of 0.5MG/5ML

  • Bottle 240ML of 0.5MG/5ML

  • Bottle 500ML of 0.5MG/5ML

  • Disp Pack 21 Tablets Therapy Pack

  • Disp Pack 35 Tablets Therapy Pack

  • Disp Pack 51 Tablets Therapy Pack

Common Dexamethasone prescriptions

  • dexAMETHasone
    237ml of 0.5mg/5ml bottle

  • dexAMETHasone
    240ml of 0.5mg/5ml bottle

  • dexAMETHasone
    500ml of 0.5mg/5ml bottle

  • dexAMETHasone
    21 tablets therapy pack disp pack

  • dexAMETHasone
    35 tablets therapy pack disp pack

  • dexAMETHasone
    51 tablets therapy pack disp pack

  • dexAMETHasone
    0.5mg tablet

  • dexAMETHasone
    0.75mg tablet

  • dexAMETHasone
    1.5mg tablet

  • dexAMETHasone
    1mg tablet

  • dexAMETHasone
    2mg tablet

  • dexAMETHasone
    4mg tablet

  • dexAMETHasone
    6mg tablet

How to take Dexamethasone

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. If you are using this medicine for an ongoing illness, your dose may need to be changed occasionally.

  • Oral routeIt is best to take this medicine with food or milk.

  • Hemady„¢: May be taken with or without food.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: If your schedule is one dose every other day and you cannot use the missed dose until late in the day, wait until the next morning to use your medicine. Then skip a day and go back to your regular schedule.If your schedule is one dose every day, use the missed dose as soon as you can. Then go back to your regular schedule.If your schedule is more than one dose every day, use the missed dose as soon as you can. If it is almost time for your next dose, use two doses at that time. Then go back to your regular schedule.

  • Missed dose: If your schedule is one dose every other day and you cannot use the missed dose until late in the day, wait until the next morning to use your medicine. Then skip a day and go back to your regular schedule.If your schedule is one dose every day, use the missed dose as soon as you can. Then go back to your regular schedule.If your schedule is more than one dose every day, use the missed dose as soon as you can. If it is almost time for your next dose, use two doses at that time. Then go back to your regular schedule.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. If you are using this medicine for an ongoing illness, your dose may need to be changed occasionally.

  • Oral routeIt is best to take this medicine with food or milk.

  • Hemady„¢: May be taken with or without food.

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Dexamethasone

  • Store the medicine at room temperature, away from heat, moisture, and direct light.

Dexamethasone contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to dexamethasone, or if you have a fungal infection.

Dexamethasone warnings

  • Using Hemady„¢ while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment and for 1 month after your last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

  • Do not breastfeed during treatment with Hemady„¢ and for 2 weeks after your last dose.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease (including cirrhosis), adrenal gland problems, blood clots, diabetes, eye or vision problems, heart failure, high blood pressure, myasthenia gravis, osteoporosis, stomach or bowel problems (including ulcer, diverticulitis), thyroid problems, depression, mental health problems, or a recent heart attack.

  • This medicine may cause the following problems:High blood pressureEye or vision problems (including cataracts or glaucoma), with long-term useIncreased risk for cancer (including Kaposi€™s sarcoma)Adrenal gland problemsStomach or bowel perforation (tear or hole)Bone problems (including osteoporosis)Muscle problemsSlow growth in childrenChanges in mood or behavior

  • This medicine could cause you to get infections more easily. Tell your doctor right away if you have any type of infection (including herpes eye infection, tuberculosis, or threadworm) or a recent exposure to chickenpox or measles. Tell your doctor if you have an infection that keeps coming back.

  • If you use this medicine for a long time, tell your doctor about any extra stress or anxiety in your life, including other health concerns and emotional stress. Your dose might need to be changed for a short time while you have extra stress.

  • Talk with your doctor before using this medicine if you plan to have children. Some men who is taking Hemady„¢ have become infertile (unable to have children).

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Dexamethasone interactions

  • Some medicines can affect how dexamethasone works. Tell your doctor if you are using any of the following:Aminoglutethimide, aprepitant, carbamazepine, carfilzomib, cholestyramine, cobicistat, cyclosporine, digitalis, digoxin, ephedrine, indinavir, indomethacin, lenalidomide, pancuronium, phenobarbital, phenytoin, pomalidomide, ritonavir, thalidomideBirth control pills (including estrogen)Blood thinner (including warfarin)Diuretic (water pill)Insulin and oral diabetes medicineMedicine to treat an infection (including amphotericin B, azithromycin, clarithromycin, erythromycin, isoniazid, itraconazole, ketoconazole, rifampin)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, naproxen)Potassium supplement

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

  • Let your doctor know if you have any events causing unusual stress or anxiety in your life. Your dose of this medicine may need to be changed.

  • It may be easier for you to get an infection while you are receiving dexamethasone. Avoid people who are sick or have infections. If you are exposed to chickenpox or measles, tell your doctor right away.

  • Carefully follow any diet instructions your doctor gives you while you are using dexamethasone.

  • Make sure any doctor or dentist who treats you knows that you are using dexamethasone.

  • Your doctor may need to check you at regular visits to make sure this medicine is working properly. Keep all your appointments.

Dexamethasone side effects

Serious Side Effects

  • Skin changes or growths

  • Unexplained muscle pain, tenderness, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or other changes in vision, trouble seeing, eye pain

  • Bone pain, decrease in height

  • Chest pain, trouble breathing, coughing up blood

  • Dark freckles, skin color changes, coldness, weakness, tiredness, weight loss

  • Depression, unusual thoughts, feelings, or behaviors, trouble sleeping

  • Fever, chills, cough, sore throat, body aches

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Unusual bleeding or bruising

  • Severe stomach pain, nausea, vomiting, or red or black stools

Less Serious Side Effects

  • Round, puffy face

  • Weight gain around your neck, upper back, breast, face, or waist