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EspañolDesmopressin Acetate Spray overview
BRAND NAMES:
DDAVP, DDAVP Rhinal Tube, Noctiva, Stimate, Stimate
Generic Names:
Desmopressin Acetate Spray
Uses:
Treats thirst and frequent urination caused by central diabetes insipidus or brain injuries. Treats bleeding disorders (including hemophilia A and von Willebrand disease). Also treats nocturnal polyuria (frequent urination and increased volume of urine at night).
Therapeutic Classes:
Endocrine-Metabolic Agent, Hemostatic
Forms:
Spray, Drop
How it’s taken:
Into the nose
What is Desmopressin Acetate Spray used for?
DDAVP is a man-made form of a hormone called vasopressin. Vasopressin controls the amount of urine the body makes. DDAVP replaces low levels of Vasopressin and controls the amount of urine your kidneys make.
What form(s) does Desmopressin Acetate Spray come in
Spray
Drop
What are common Desmopressin Acetate Spray doses?
Bottle 5ML of 0.01%
Common Desmopressin Acetate Spray prescriptions
Desmopressin Acetate Spray
5ml of 0.01% bottle
How to take Desmopressin Acetate Spray
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.
DDAVP® or desmopressin generic: Prime the spray bottle the first time you use it by spraying 4 times into the air, away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 50 sprays.
DDAVP® Rhinal Tube System: This is a soft plastic tube with numbers (doses) marked on the side. Draw the drops into the tube until the liquid reaches the number for your dose. Put one end of the tube into your nose and the other end into your mouth. Blow gently until the medicine is sprayed into your nose. Do not let any medicine run down through the tube into your mouth.
Noctiva„¢: Prime the spray bottle the first time by spraying 5 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 2 sprays if you do not use the bottle for more than 3 days.Throw away the bottle and any unused medicine 60 days after opening.
Stimate®: Prime the spray bottle the first time by spraying 4 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 25 sprays.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Noctiva„¢: If you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.
DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.
Stimate®: Prime the spray bottle the first time by spraying 4 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 25 sprays.
DDAVP® or desmopressin generic: Prime the spray bottle the first time you use it by spraying 4 times into the air, away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 50 sprays.
DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Noctiva„¢: If you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.
DDAVP® Rhinal Tube System: This is a soft plastic tube with numbers (doses) marked on the side. Draw the drops into the tube until the liquid reaches the number for your dose. Put one end of the tube into your nose and the other end into your mouth. Blow gently until the medicine is sprayed into your nose. Do not let any medicine run down through the tube into your mouth.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Noctiva„¢: Prime the spray bottle the first time by spraying 5 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 2 sprays if you do not use the bottle for more than 3 days.Throw away the bottle and any unused medicine 60 days after opening.
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.
DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.
Desmopressin Acetate Spray contraindications
This medicine is not right for everyone. Do not use it if you had an allergic reaction to desmopressin. Do not use Noctiva„¢ if you are thirsty most of the time and drink large amounts of fluids, wet the bed while sleeping at night, or have a condition called syndrome of inappropriate antidiuretic hormone.
Desmopressin Acetate Spray warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, cystic fibrosis, a nose injury or infection, head injury, or trouble urinating. Tell your doctor about all heart, circulation, or blood problems you have, including heart failure, high blood pressure, or a history of blood clots, heart attack, or stroke.
This medicine may cause the following problems:Fluid retention (swelling)High blood pressureBlood clotting problems
Your doctor may limit the amount of fluid or water you drink each day, because this medicine will affect how your body stores water.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. For patients with nocturnal polyuria: Your doctor will need to measure your urine and the times that you urinate for 24 hours.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Severe headache that does not go away
Desmopressin Acetate Spray interactions
Do not use Noctiva„¢ together with certain diuretic (water pill, including furosemide, torsemide) or systemic or inhaled glucocorticoids (including dexamethasone, fluticasone, methylprednisolone, prednisolone, prednisone).
Some medicines can affect how desmopressin works. Tell your doctor if you are using any of the following:Carbamazepine, chlorpromazine, hydrochlorothiazide, lamotrigineBlood pressure medicineMedicine to treat anxietyMedicine to treat depression (including SSRIs, TCAs)Medicine to treat an overactive bladderNarcotic pain relieverNSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen).
Your doctor may limit the amount of fluid or water you drink each day, because this medicine will affect how your body stores water.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Desmopressin Acetate Spray side effects
Serious Side Effects
Nosebleeds, painful nostrils
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Confusion, weakness, muscle twitching or spasms, seizures
Rapid weight gain, swelling of your feet, legs, or ankles
Severe headache that does not go away
Nausea, loss of appetite, vomiting that does not go away
Less Serious Side Effects
Runny or stuffy nose
Mild nausea or stomach pain