What is Clonazepam: Uses, Warnings & Interactions

Updated Mar 25, 2024  •  Published Dec 30, 2020

Clonazepam overview

BRAND NAMES:

  • Klonopin

Generic Names:

  • Clonazepam

Uses:

  • Treats seizures and panic disorder.

Therapeutic Classes:

  • Benzodiazepine, anticonvulsant, anxiolytic

Forms:

  • Tablet, orally disintegrating tablet

How it’s taken:

  • By mouth

What is Clonazepam used for?

The FDA has approved clonazepam as a treatment for seizure disorders in children and adults as well as a treatment for panic disorder in adults. Nevertheless, healthcare providers frequently prescribe clonazepam for off-label, unapproved uses such as restless legs syndrome, movement disorders, anxiety, insomnia, sleepwalking, Tourette syndrome, and other medical conditions. 

What form(s) does Clonazepam come in

  • Tablet

    • 0.5 mg

    • 1 mg

    • 2 mg

  • Orally disintegrating tablet

    • 0.125 mg

    • 0.25 mg

    • 0.5 mg

    • 1 mg

    • 2 mg

What are common Clonazepam doses?

  • For seizure disorders in adults and children 10 years of age and older: 0.5–5 mg tablet taken 3 times daily

  • For seizure disorders in children younger than 10 years of age: 0.1–0.2 mg/kg per day divided into 2 or 3 daily doses

  • For panic disorder in adults: 0.5–2 mg tablet taken 2 times daily

Common Clonazepam prescriptions

  • clonazePAM
    0.5mg tablet

  • clonazePAM
    1mg tablet

  • clonazePAM
    2mg tablet

  • clonazePAM
    0.125mg tablet disintegrating

  • clonazePAM
    0.25mg tablet disintegrating

  • clonazePAM
    0.5mg tablet disintegrating

  • clonazePAM
    1mg tablet disintegrating

  • clonazePAM
    2mg tablet disintegrating

How to take Clonazepam

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • This medication is required by law to include a medication guide. It contains important information you should know. Please read this guide before taking clonazepam.

  • Do not stop taking clonazepam suddenly. Doing so may cause serious side effects. If the medicine does not seem to work or side effects are a problem, get medical advice from the prescribing healthcare provider about discontinuing this medication.

  • How to take clonazepam tablets

    • Swallow the tablet whole with a drink of water.

  • How to take clonazepam orally disintegrating tablets

    • Make sure your hands are dry before you handle the disintegrating tablet. 

    • Do not remove a tablet from the blister pack until you’re ready to take the tablet.

    • Be careful opening the blister pack. Don’t push the tablet through the foil, but instead, tear the foil and gently remove the tablet from the blister pack.

    • Place the tablet on your tongue and let it dissolve.

  • Store clonazepam tablets or orally disintegrating tablets at room temperature in a child-proof, closed container out of the reach of children.

What to do if you miss a dose of Clonazepam

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. 

  • Do not take extra medicine to make up for a missed dose.

Clonazepam contraindications

  • This medicine is not right for everyone. 

  • Do not use it if you have:

    • Severe liver disease

    • Narrow-angle glaucoma

    • Had an allergic reaction to clonazepam or similar medicines called benzodiazepines.

Clonazepam warnings

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine.

  • Your doctor will regularly check in with you and do lab tests to monitor the effects of this medicine. Keep all appointments.

  • Too much of this medicine can be fatal. Get emergency medical care if too much clonazepam is taken. Symptoms of an overdose include extreme dizziness, weakness, trouble breathing, slow heartbeat, seizures, and cold, clammy skin.

  • Clonazepam can cause physical dependency and become habit-forming. When clonazepam is taken inappropriately, overdose and death are possible. Do not use more than your prescribed dose or take clonazepam for longer than prescribed. Call your doctor if you think your medicine is not working.

  • Tell your doctor if you have:

    • Liver disease

    • Kidney disease

    • Lung or breathing problems such as COPD or sleep apnea

    • Glaucoma

    • Porphyria

    • A history of depression, mood problems, other mental health problems, or suicidal thoughts or behaviors

    • A history of drug or alcohol abuse

  • This medicine can increase thoughts of suicide. Tell the doctor right away if you start to feel depressed and have thoughts about hurting yourself.

  • It may not be safe to take this medicine during pregnancy. Tell your doctor if you are pregnant or plan on becoming pregnant.

  • Tell the doctor if you are breastfeeding or planning to breastfeed. Clonazepam can make a nursing infant sleepy or less willing to feed.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that’s risky until you know how this medicine affects you.

  • Clonazepam is a federally controlled substance. Giving or selling this drug to anyone else is dangerous and against the law.

  • Because of the risk of overdose, death, or misuse, keep clonazepam securely out of the reach of children.

Clonazepam interactions

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use before taking clonazepam.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

  • Taking clonazepam along with opioids can cause serious problems including slowed breathing, coma, and death.

  • Because clonazepam has sedative effects, it can cause excessive sleepiness, impairment, and even slowed breathing when combined with other drugs that cause sleepiness including other benzodiazepines, antidepressants, antihistamines, or alcohol. 

  • Do not drink alcohol when taking clonazepam.

  • Before taking clonazepam, tell the prescribing doctor if you are using any of the following medicines:

    • Mental health medications 

    • Seizure medications

    • A type of drug called MAO inhibitors (MAOIs)

    • Other anti-seizure drugs including carbamazepine, phenytoin, and phenobarbital

    • Oral drugs that treat fungal infections

    • Phenothiazine drugs

Clonazepam side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Blue lips, fingernails, or skin

  • Extreme drowsiness or weakness, slow heartbeat, trouble breathing

  • Confusion, lightheadedness, dizziness, problems with muscle control or coordination

  • Unusual mood or behavior, worsening depression, thoughts about hurting yourself, trouble sleeping

  • Seizures or worsening seizures

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Drowsiness or sleepiness

  • Dizziness

  • Weakness

Find more detailed information about clonazepam side effects here.

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