What is Benzonatate: Uses, Warnings & Interactions

Updated Feb 1, 2024  •  Published Dec 30, 2020

Benzonatate overview

BRAND NAMES:

  • Tessalon Perles

Generic Names:

  • Benzonatate

Uses:

  • Treats cough

Therapeutic Classes:

  • Antitussive, non-opioid antitussive

Forms:

  • Liquid-filled capsule

How it’s taken:

  • By mouth

What is Benzonatate used for?

Benzonatate is used to relieve coughing.

What form(s) does Benzonatate come in

  • Liquid-filled capsule

    • 100 mg

    • 150 mg

    • 200 mg

What are common Benzonatate doses?

  • For the symptomatic relief of cough in adults and children 10 years of age and older: 100–200 mg capsule taken three times per day

RELATED: Benzonatate dosage, forms, and strengths

Common Benzonatate prescriptions

  • Benzonatate
    100mg capsule

  • Benzonatate
    150mg capsule

  • Benzonatate
    200mg capsule

How to take Benzonatate

  • Follow all instructions from the healthcare provider, pharmacist, or medication label when taking benzonatate.

  • Your doctor will tell you how much medicine to take and how often.

  • Do not exceed the prescribed dose. 

  • Swallow the capsules whole. Do not crush, chew, bite, or suck on the capsule.

  • Store benzonatate at room temperature (68°–77°F) protected from light.

What to do if you miss a dose of Benzonatate

  • Take the missed dose as soon as possible. If it is almost time for the next dose, wait until then to take your medicine and skip the missed dose.

  • You should not take two doses at the same time.

Benzonatate contraindications

  • This medicine is not right for everyone. 

  • You should not use this medicine if you have had an allergic reaction to benzonatate in the past.

Benzonatate warnings

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine.

  • Do not crush, chew, bite, or suck on the capsule. Doing so can quickly numb the mouth and throat, cause difficulty swallowing, and create a choking hazard. It can also cause severe hypersensitivity reactions such as inability to breathe or severely low blood pressure.

  • If tingling or numbness is felt in the mouth, throat, or face, do not eat or drink until the numbness stops. If the numbness doesn’t go away, get emergency medical attention.

  • Benzonatate is not recommended for children younger than 10 years old.

  • Young children have died when they have accidentally ingested benzonatate capsules. Always store this medication in a child-resistant container out of the reach of children at all times.

Benzonatate interactions

  • There are no reported drug interactions with benzonatate.

  • However, always tell the prescribing healthcare provider about all prescription drugs, over-the-counter medicines, and supplements you are using before taking benzonatate.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

Benzonatate side effects

Serious side effects

Benzonatate can cause serious side effects due to allergies or taking the drug incorrectly. Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Facial numbness, throat numbness, trouble swallowing, and choking

  • Confusion, hallucinations

  • Allergic reaction: throat closure, airway closure, low blood pressure, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Nausea

  • Upset stomach

  • Drowsiness

  • Mild dizziness

  • Headache

  • Constipation

  • Stuffy nose

  • Eye irritation

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