What is Amphotericin B: Uses, Warnings & Interactions

Updated Jan 12, 2021  •  Published Dec 30, 2020

Amphotericin B overview

Generic Names:

  • Amphotericin B

Uses:

  • Treats infections caused by a fungus.

Therapeutic Classes:

  • Antifungal, Antiprotozoal

Forms:

  • Injectable

How it’s taken:

  • By injection

What form(s) does Amphotericin B come in

  • Injectable

What are common Amphotericin B doses?

  • Solution Reconstituted 50MG

  • Jar 1GM of 905UNIT/MG

Common Amphotericin B prescriptions

  • Amphotericin B
    50mg solution reconstituted

How to take Amphotericin B

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

Amphotericin B contraindications

  • This medicine is not right for everyone. Do not receive it if you had an allergic reaction to amphotericin B.

Amphotericin B warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Change in how much or how often you urinate

  • Dry mouth, increased thirst, muscle cramps

  • Fast, slow, or uneven heartbeat

  • Severe nausea and vomiting

  • Shaking, fever, and chills

  • Swelling of the hands, ankles, or feet

  • Trouble breathing

Amphotericin B interactions

  • Some medicines can affect how amphotericin B works. Tell your doctor if you are taking any of the following: Antibiotic medicineCorticosteroid medicine, such as prednisone or cortisoneDigoxinDiuretic medicine (water pills)Other antifungal medicine

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Amphotericin B side effects

Serious Side Effects

  • Shaking, fever, and chills

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate

  • Severe nausea and vomiting

  • Trouble breathing

  • Swelling of the hands, ankles, or feet

  • Blistering, peeling, red skin rash

  • Fast, slow, or uneven heartbeat

  • Dry mouth, increased thirst, muscle cramps

Less Serious Side Effects

  • Swelling, pain, or redness near where the IV needle is placed