What is Invokana: Uses, Warnings & Interactions

Updated Jan 25, 2023  •  Published Jan 25, 2023

Invokana overview

BRAND NAMES:

  • Invokana

Generic Names:

  • Invokana

Uses:

  • Treats type 2 diabetes. Also lowers the risk of death, end stage kidney disease, heart attack, or stroke in patients with type 2 diabetes and heart or blood vessel problems.

Therapeutic Classes:

  • Endocrine-Metabolic Agent, Hypoglycemic

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Invokana used for?

Invokana is a medication used to treat type 2 diabetes. This drug belongs to the gliflozin or SGLT2 class of medicaitons. Invokana acts by increasing the amount of sugar eliminated in the urine. Invokana is a brand version of the drug canagliflozin. This medication was the first of its kind to be approved by the US FDA (approval date March 29, 2013). In the treatment of type 2 diabetes, Invokana use is common.

What form(s) does Invokana come in

  • Tablet

What are common Invokana doses?

  • Tablet 100mg

  • Tablet 300mg

Common Invokana prescriptions

  • Invokana
    100mg tablet

  • Invokana
    300mg tablet

How to take Invokana

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine before the first meal of the day.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Invokana contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to canagliflozin.

Invokana warnings

  • Tell your doctor if you are pregnant. Do not use this medicine during the second and third part of your pregnancy, unless your doctor tells you to.

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, blood vessel disease, high cholesterol, nerve problems, or a history of pancreas problems, genital yeast or urinary tract infections, leg surgery, or foot ulcers. Tell your doctor if you are on a low-salt diet or if you drink alcohol.

  • This medicine may cause the following problems: Increased risk for leg, toe, or midfoot amputation (removal)Low blood pressureKetoacidosis (high ketones and acid in the blood)Kidney problemsIncreased risk of genital yeast or urinary tract infectionsLow blood sugar, when used with other diabetes medicinesFournier's gangrene (skin or tissue damage of the area between the anus and genitals)Increased risk of broken bonesHigh cholesterol level

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Trouble breathing, tiredness, stomach pain, nausea, vomiting

Invokana interactions

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. This medicine may affect the results of urine glucose tests.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Some medicines can affect how canagliflozin works. Tell your doctor if you are using any of the following: Digoxin, phenobarbital, phenytoin, rifampin, ritonavirBlood pressure medicineDiuretic (water pill)Insulin or other diabetes medicineNSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen)

  • Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.

Invokana side effects

Serious Side Effects

  • Pain, tenderness, redness, or swelling of the area between the anus and genitals, fever, unusual tiredness or weakness

  • Pain, tenderness, sores or ulcers, or infections on the leg or foot

  • Fast or troubled breathing, stomach pain, nausea, vomiting

  • Increased hunger, headache, confusion, shaking, trembling, sweating

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate, bloody urine, painful or difficult urination, lower back or side pain, chills

  • Confusion, severe weakness, uneven heartbeat, numbness in your hands, feet, or lips

  • Lightheadedness, dizziness, fainting

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • White or yellow vaginal discharge, vaginal itching or odor

  • Redness, itching, pain, or swelling of the penis, bad-smelling discharge from the penis