What is Cetirizine Hcl: Uses, Warnings & Interactions

Updated Mar 7, 2024  •  Published Dec 30, 2020

Cetirizine Hcl overview

BRAND NAMES:

  • Zyrtec, Quzyttir (Rx), Zerviate (Rx), Aller-Tec Allergy, Wal-Zyr, Aller-Zyr, Cetiramed

Generic Names:

  • Cetirizine HCl

Uses:

  • Treats hay fever and upper respiratory allergy symptoms, hives, and ocular itching

Therapeutic Classes:

  • Antihistamine, second generation antihistamine

Forms:

  • Capsule, tablet, chewable tablet, orally disintegrating tablet, oral solution (liquid), syrup, eye drops, injection

How it’s taken:

  • By mouth, topically (eyes), intravenous injection

What is Cetirizine Hcl used for?

Cetirizine relieves the symptoms of hay fever, other upper respiratory allergies, and hives. Healthcare providers use prescription cetirizine to treat hives or itchy eyes.

What form(s) does Cetirizine Hcl come in

  • Capsule

    • 10 mg

  • Tablet

    • 5 mg

    • 10 mg

  • Chewable Tablet

    • 5 mg

    • 10 mg

  • Orally disintegrating tablet

    • 10 mg

  • Oral solution (liquid)

    • 1 mg/mL

  • Syrup

    • 1 mg/mL

  • Eye drops

    • 0.24% (2.4 mg/mL)

  • Injection

    • 10 mg/mL

What are common Cetirizine Hcl doses?

  • Standard adult dosage for allergies or hay fever: 10 mg taken once daily by mouth as needed

  • Standard adult dosage for hives: 5–10 mg taken once daily by mouth as needed

  • Standard adult dosage for allergic conjunctivitis: One drop placed in each affected eye twice daily and administered eight hours apart

  • Find children’s dosages and more information about cetirizine dosage, forms, and strengths here

Common Cetirizine Hcl prescriptions

  • Cetirizine HCl
    1 tablets chewable blister

  • Cetirizine HCl
    100 tablets bottle

  • Cetirizine HCl
    120ml of 1mg/ml bottle

  • Cetirizine HCl
    14 tablets bottle

  • Cetirizine HCl
    30 tablets bottle

  • Cetirizine HCl
    30 tablets chewable bottle

  • Cetirizine HCl
    300 tablets bottle

  • Cetirizine HCl
    45 tablets bottle

  • Cetirizine HCl
    473ml of 1mg/ml bottle

  • Cetirizine HCl
    480ml of 1mg/ml bottle

  • Cetirizine HCl
    500 tablets bottle

  • Cetirizine HCl
    90 tablets bottle

  • Cetirizine HCl
    14 tablets box

  • Cetirizine HCl
    30 tablets box

  • Cetirizine HCl
    30 tablets chewable box

  • Cetirizine HCl
    90 tablets box

  • Cetirizine HCl
    10mg tablet

  • Cetirizine HCl
    5mg tablet chewable

How to take Cetirizine Hcl

  • Follow the instructions on the package.

  • Do not take more than instructed.

  • Talk to a doctor before giving cetirizine to a child younger than 6 years of age

  • How to take cetirizine tablets or capsules

    • Swallow the tablet or capsule whole with a full glass of water. Do not chew, crush, or break it.

    • Chewable tablets can be taken with or without water. Chew the tablet thoroughly before you swallow it. You may also let the chewable tablet melt slowly in your mouth.

    • Orally dissolving tablets can be taken with or without water. Allow the tablet to dissolve in the mouth fully.

    • Store cetirizine tablets and capsules at room temperature protected from humidity, heat, and light.

  • How to take cetirizine oral solution or syrup

    • You do not need to shake the bottle.

    • Measure the liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. A measuring device should come with the medicine. If you don’t have one, ask the pharmacist.

    • Store the oral solution or syrup at room temperature.

  • How to administer cetirizine eye drops

    • Wash your hands before administering the drops.

    • Take out any contact lenses before administering cetirizine eye drops.

    • To avoid infection, do not touch the tip of the bottle to the eye or eyelid.

    • If using single-use containers, use them immediately after removing them from the foil wrapping.

    • The single-use containers can be used to dose both eyes.

    • When applying drops, pull down on the lower eyelid and put the drop in the pocket between the eye and the eyelid. 

    • Discard the single-use containers after dosing the eyes. Do not save for later use even if there’s medicine left over.

    • Store cetirizine eye drops at room temperature.

What to do if you miss a dose of Cetirizine Hcl

  • For OTC cetirizine, take only one dose per day.

  • If you forget to take a day’s dose, take it on the same day if you still have symptoms.

  • If it’s the next day and you still have symptoms, do not take a missed dose. Take a dose for the current day. 

  • Do not take two doses to make up for a missed dose.

  • If you’re using prescription cetirizine or administering OTC cetirizine under the direction of a doctor, ask the doctor what to do if a dose is missed.

Cetirizine Hcl contraindications

  • You should not use this medicine if you have had an allergic reaction to cetirizine or hydroxyzine.

Cetirizine Hcl warnings

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine.

  • Do not give cetirizine to a child younger than 6 years old except under the advice and direction of a doctor.

  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • Talk with your doctor before taking this medicine if you are pregnant or breastfeeding.

  • Check with your doctor before using this medicine if you have kidney disease or liver disease.

  • Cetirizine syrup, oral solution, chewable tablets, and orally disintegrating tablets are sweetened and flavored. To avoid accidental overdose, keep them out of the reach of children. Make sure the child-proof cap is securely fastened on the top of the solution or syrup bottle.

Cetirizine Hcl interactions

  • Because of possible drug interactions, tell other healthcare providers you are using this medicine before they prescribe any medication.

  • If you’re taking the asthma and COPD medication theophylline, ask a doctor for medical advice before taking cetirizine.

  • Since cetirizine commonly causes drowsiness, try to avoid taking other drugs that make you sleepy such as other antihistamines, sedatives, narcotic pain relievers, sleeping pills, or muscle relaxants.

  • Avoid drinking alcohol while using this medicine.

Cetirizine Hcl side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

Find more detailed information about Zyrtec side effects here.